This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Microbe-host epithelial cell interactions can promote or diminish the health of an epithelial barrier. The microbes and cells of the cervix and vagina are no exception. For example, high levels of Gardnerella vaginalis can lead to bacterial vaginosis, STDs, and preterm birth, while the presence of Lactobacillus species is usually associated with a healthy reproductive system. The host-microbiome interactions affecting cervicovaginal (CV) epithelial function were studied using CV epithelial cells mixed with G. vaginalis or Lactobacillus crispatus. G. vaginalis, but not L. crispatus, increased CV epithelial cell death. and G. vaginalis mediated an immune response in CV cells, partially through TLR2-dependent signaling pathways. In human CV fluid, cytokine immune profiling showed distinctive clustering of cytokines by Gardnerella spp. abundance and birth outcome..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This presentation provides an introduction and explores the trends in the five sexual and reproductive health priority areas over the last decades:
Maternal and newborn health, family planning, unsafe abortion, sexually transmitted infections and sexual health.

This video introduces the content and the history that has led to the definition of the broad approach called sexual and reproductive health and rights. It has developed from use of contraception and the rights and knowledge to decide how many children a family wants, over maternal mortality during birth and sexual transmission of diseases. Today the area also includes discussions of sexual orientation, relations outside marriage and early marriage.

This presentation provides an introduction to the innovative use of technology to improve maternal and child health in low and middle income countries. Two of the major challenges in relation to reproductive and child health is access to health services and the quality of services provided in the health system. In continuation of this we’ll look into how mobile phone interventions can strengthen access to and quality of life saving interventions particularly in the time surrounding the delivery when the woman and the newborns are most vulnerable.

This is a simple assignment for students in an introductory course on global health, by Dr. Jennifer Infanti (Norwegian University of Science and Technology). The students are divided into small groups. Working in the groups, they have 48 hours to present “solutions” to an assigned topic: to increase contraceptive use in rural areas of low-income countries. The groups each present their solutions to an evaluating committee and give peer feedback as well. Suggested evaluation criteria for teachers/assessors is also attached.After completing this assignment students will be able to:Describe various reproductive health problems occurring during the different stages in life (childhood, adolescence, adulthood).Identify, for each stage, hindrances to optimal sexual and reproductive health including socio-economic, family and health care factors.Suggest short- and long-term actions which could be implemented to improve reproductive health at different levels in low-resource settings (with a gender perspective). 

This page provides access to resources related to supporting the sexual and reproductive health and wellness of youth in foster care, with paricular emphasis on youth served by human services agencies in the state of California.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Premature ovarian failure (POF) is a leading cause of female infertility, and there are no effective treatments. Although the pathogenesis is unclear, it appears to involve dysregulated signaling between BDNF and its receptor TrkB. However, BDNF can’t be used as a drug, so TrkB has never been considered as a therapeutic target for POF—until now. In a new study, researchers tested the effects of a TrkB agonist antibody, Ab4B19, in mice with POF induced by natural aging or cyclophosphamide. In both POF models, Ab4B19 increased the numbers of preantral and antral follicles and normalized gonadal hormone levels, ultimately improving fertility. Ab4B19 also attenuated gonadotoxicity and apoptosis in cyclophosphamide-treated mice. Further studies revealed that BDNF and TrkB expression were highly increased in human ovarian follicles during folliculogenesis, confirming the important role of BDNF-TrkB signaling in normal fertility. In contrast, in follicles of aged women, BDNF expression was downregulated..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The composition of the vaginal microbiome is associated with pregnancy complications. However, it’s unclear whether the microbiome of the uterine lining (endometrium) is related to specific outcomes in patients undergoing assisted reproductive technology (ART). To find out, researchers recently analyzed the association of the endometrial microbiome with live birth, biochemical pregnancy, clinical miscarriage, and lack of pregnancy in 342 ethnically diverse infertile patients across 3 continents. 16S rRNA sequencing of endometrial fluid and biopsies before embryo transfer revealed that dysbiosis was related to poor reproductive outcomes. Specifically, increased proportions of pathogenic bacteria such as Gardnerella, Streptococcus, Atopobium, and Klebsiella were associated with a lack of live birth, while dominance of Lactobacillus bacteria was associated with live birth..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cervicovaginal bacterial communities are closely linked to reproductive health. Communities characterized by diverse anaerobes and low Lactobacillus abundance are associated with preterm birth, infertility, and risk of sexually transmitted infections (STIs). Women in South Africa are more likely to have these 'high-risk' bacterial communities than women in the U.S. and Europe. But the transition between high- and low-risk community states is not well understood. To examine this, researchers profiled the cervicovaginal bacterial communities of healthy young Black South African women over time. They developed a Markov-based model of transition dynamics that accurately predicted bacterial composition in a separate cross-sectional cohort. While communities with high levels of Lactobacillus spp..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.