This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A recent study published in Acta Neuropathologica Communications has found a potential mechanism for the initiation and development of Parkinson’s disease and it appears red blood cells may be partly to blame. Parkinson’s is a chronic and progressive neurodegenerative disorder commonly associated with tremors, muscle stiffness, and impaired movement. While these symptoms are caused by the deterioration of nerve cells in the brain, the precise cause of the disease is still not fully understood. What is known is that the development of Parkinson’s is associated with the aggregation of toxic forms of a protein named alpha-synuclein (or alpha-syn, for short) in the brain. Recent evidence, however, suggests alpha-syn found in the blood can also be problematic and this has been implicated as a contributor to brain-cell breakdown..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This 15-minute video lesson examines hemoglobin and its role in the circulatory system. [Biology playlist: Lesson 40 of 71].

This 16-minute video looks at oxygen uptake by hemoglobin in red blood cells. [Biology playlist: Lesson 38 of 71].

Students will make a proportional model of blood out of red gelatin, a plastic bag, and rice. They will learn about the different components that make up blood and will investigate what happens when the arteries and veins experience buildup from cholesterol. They will then work in pairs to brainstorm ways to clean our clogged arteries.

This video shows scanning a Wright's stained blood smear slide with pauses to view leukocytes. The video was taken at 630X under a brightfield microscope. This video is compatible with a laboratory lesson in which students observe, categorize, and count leukocytes. More than 100 leukocytes are viewed in this video. Note, this video does not have narration.Video credit: Emily Fox

Red Blood Cells also known as red blood cells (RBCs) or erythrocytes are around 7.5μm in diameter. The average number (red blood cell count) is typically:
*5,200,000 per cubic millimeter ± 300,000 men
*4,700,000 per cubic millimeter ± 300,000 women

Red blood cells are made of hemoglobin. When the hemoglobin combines with oxygen it is called oxyhemoglobin, when oxygen has been released it is known as deoxyhemoglobin. The RBC initially have a nuclei during the early stages of development, they then remove the nuclei to help make room for hemoglobin.

Lesson 4 in our Cardiovascular System (Blood) series. This is part of our Anatomy and Physiology lecture series.

If this video helps you please be sure to LST -like subscribe and tell your friends. Your support helps us make more videos. For the complete series please visit http://mrfordsclass.net/

Blood Videos
-Introduction to Blood (13:01): http://youtu.be/-Y5U49E-CM4
-Composition of Blood (13:02): http://youtu.be/YHCIMKZ0zrg
-Hematopoiesis-Making Blood (13:03): http://youtu.be/sibrcrXHJGI
-Red Blood Cells (13:04): http://youtu.be/19_6kUCVYfk

Heart and Blood Vessels Videos
-Heart Fundamentals (14:01): http://youtu.be/Y335KJ-EuDw
-Layers of the Heart (14:02): http://youtu.be/8PlwFTwJRMQ
-Chambers in the Heart (14:03): http://youtu.be/SdNQtPzUfHg
-Introduction to Blood Vessels (14:08): http://youtu.be/GVs8cd6jv94
-Types of Blood Vessels (14:09): http://youtu.be/_jkQR8v-bAg
-Movement of Blood (14:11): http://youtu.be/x9dH5TpKntk

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Thrombospondin-1, or TSP-1, is a calcium-binding protein implicated in the development of several diseases, including diabetes, cancer, renal failure, and cardiovascular disease. To understand TSP-1’s role in disease, researchers recently examined the protein’s effects on the calcium dynamics, survival, and deformability of red blood cells. In vitro experiments showed that exposure to recombinant human TSP-1 significantly increased calcium levels in red blood cells. TSP-1 treatment also induced an inward ionic current, suggesting possible calcium influx through non-selective cation channels, and TSP-1 caused the deformation of red blood cells. Further experiments revealed that TSP-1 binding to its receptor CD47 could dictate the lifespan of red blood cells in circulation. Altogether, the findings suggest that TSP-1/CD47 signaling could be one targetable pathway in systemic diseases that attack red blood cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Also known as red blood cells (RBCs). Erythrocytes deliver oxygen to, and remove carbon dioxide from tissues. Erythrocytes are derived from the stem cell (CFU-GEMM) and formed in a process known as erythropoiesis.

This programme demonstrates in a video lesson the procedure in determining whether there is adequate number of red blood cell in circulation. The procedure covers the description of the laboratory instruments and materials that are used in such tests. At the end of the procedure, an observation of the test result is made and interpreted with the use of a microscope.

This lesson describes how the circulatory system works, including the heart, blood vessels and blood. Students learn about the chambers and valves of the heart, the difference between veins and arteries, and the different components of blood. This lesson also covers the technology engineers have developed to repair the heart if it is damaged. Students also understand how the circulatory system is affected during spaceflight (e.g., astronauts lose muscle in their heart during space travel).

Students learn about the separation techniques of sedimentation and centrifugation and investigate whether blood is a homogeneous or a heterogeneous mixture. Working in groups as if they are biomedical researchers, they employ the scientific method and make observations about the known characteristics of urine, milk and blood. They probe further by analyzing research on the properties and fractionation modes of blood. As students learn about certain strange characteristics with the fractionation behavior of blood, they formulate hypotheses on the unique nature of blood. Using provided materials —olive oil, tomato juice and petroleum jelly—they design an experiment and construct a blood model. They test their hypotheses by conducting experiments on the blood model, and then propose theories for the nature of blood as a mixture—arriving at the theory of mixture dualism in blood—that blood is a complex mixture system. An activity-guiding handout and PowerPoint® presentation are provided for this student-directed, project-based activity.

Students are presented with a short lesson on the Coulter principle—an electronic method to detect microscopic particles and determine their concentration in fluid. Depending on the focus of study, students can investigate the industrial and medical applications of particle detection, the physics of fluid flow and electric current through the apparatus, or the chemistry of the electrolytes used in the apparatus.

As taught Semesters 1 and 2, 2011

This learning object describes the structure and function and production of red blood cells. It is used as part of the level 1 Biological Sciences module delivered by the School of Nursing, Midwifery and Physiotherapy.

Dr Andy Meal, Lecturer in Biological Sciences, School of Nursing, Midwifery and Physiotherapy

Students build and use a very basic Coulter electric sensing zone particle counter to count an unknown number of particles in a sample of "paint" to determine if enough particles per ml of "paint" exist to meet a quality standard. In a lab experiment, student teams each build an apparatus and circuit, set up data acquisition equipment, make a salt-soap solution, test liquid flow in the apparatus, take data, and make graphs to count particles.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Radiation, weightlessness, and altered nutrition are just a few of the harsh conditions astronauts face while in space. Though blood parameters _do_ change during space flight, a new study published in the journal, _BMC Hematology_,_ _suggests crews on long missions may not experience persistent anemia, as once thought. Environmental conditions in space are undoubtedly different from those on Earth, and can, therefore, impact a number of the body’s systems including vision, immunity, and the musculoskeletal system. It is well understood that, upon entering microgravity, fluids rapidly shift toward the head -- evident by the so-called ‘puffy-face syndrome’ seen in many astronauts. It has been assumed that during long-duration space missions, this is accompanied by a state of anemia – a condition that occurs when the body fails to produce a sufficient levels of oxygen-carrying red blood cells and can result in weakness and fatigue..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.