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Biology
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CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Fungi decompose proteins in the world's oceans
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Terrestrial fungi are well known as decomposers, breaking down dead matter to return nutrients to the soil. However, the roles of fungi in the ocean are less well understood. Oceanic fungi occur with other microbes throughout the water column, where they break down carbohydrates. A recent study examined the role of these marine fungi in recycling proteins, which represent more than half of living and dead marine biomass. Researchers performed a multi-omics analysis of all oceanic fungal-affiliated enzymes that break down proteins (peptidases). They found that the abundance, diversity, and expression of fungal peptidases increased with ocean depth, similar to fungal carbohydrate-degrading enzymes (CAZymes). This indicates a strong link between the carbon and nitrogen cycles in the open ocean. In-depth analysis of the most widely utilised fungal proteases revealed that the majority of pelagic fungal communities are dominated by saprotrophy rather than parasitism..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/14/2023
Identifying new Helicobacter pylori HtrA targets in epithelial cells
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Gastric cancer is one of the highest mortality cancer types, and the leading cause of gastric cancer is persistent Helicobacter pylori infection. H. pylori secretes the enzyme HtrA, which cleaves adhesion proteins like E-cadherin and allows H. pylori to cross the epithelium. Recently, researchers used proteomics to find novel targets of HtrA associated with H. pylori. They confirmed E-cadherin as a target and identified human desmoglein-2 (hDsg2), neuropilin-1, ephrin-B2, and semaphorin-4D as potential targets. hDsg2 is a component of the desmosome junctions, which play important roles in epithelial cell-to-cell adhesion. Given the importance of cell-to-cell adhesion to epithelial health, the researchers focused on hDsg2. In vitro tests confirmed that HtrA secreted by H. pylori, and not other host cell proteases, cleaved hDsg2. This study is the first to demonstrate that HtrA secreted by H. pylori directly breaks down hDsg2 and suggests that HtrA is a ‘master key’ that allows H..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
03/01/2022