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Alirocumab lowers atherogenic lipids in patients with metabolic syndrome to potentially lower cardiovascular risk
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Individuals with metabolic syndrome have a 2-fold increased risk of cardiovascular disease, but few strategies provide adequate cardiovascular risk reduction for this group. One option to lower this risk is to reduce atherogenic lipids, particularly low-density lipoprotein cholesterol. Statins are a recommended first-line therapy for this purpose, but this approach doesn’t always provide sufficient LDL-C lowering to optimally reduce cardiovascular risk. Now, researchers have shown that alirocumab, a proprotein converstase subtilisin/kexin type 9 inhibitor, or PCSK9 inhibitor, approved for LDL-C reduction, may address this need. Pooled clinical trial data from ten phase 3 clinical trials from the ODYSSEY clinical development program showed alirocumab significantly lowered LDL-C in individuals both with and without metabolic syndrome..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Diabetes - The Essential Facts - Surgery, Drugs and Microchips (17:12)
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CC BY-NC-ND
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Many people exercise and take medicine in order to delay or treat type 2 diabetes. However in most cases these interventions in one’s lifestyle fails and the person regain weight and retain their increasing blood glucose levels. Controlling one’s appetite seems to be the key, which is one of the aspects we’ll discuss in this presentation. Furthermore we’ll discuss how gastric bypass surgery helps people with diabetes type 2 controlling their appetite and make their diabetes disappear. Finally we’ll discuss how hormones such as GLP-1 can help diabetics’ control their appetite, and lose weight.

Narrator: Richard Steed.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - The Essential Facts
Author:
Associate Professor Signe Sørensen Torekov
Dr Tricia Tan
MD Nicolai Wewer Albrechtsen
Professor Jens Juul Holst
Professor Steven Bloom
Date Added:
01/07/2016
Psychology
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CC BY
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Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

Subject:
Psychology
Social Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
02/14/2014
Psychology, Emotion and Motivation, Hunger and Eating
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Describe how hunger and eating are regulatedDifferentiate between levels of overweight and obesity and the associated health consequencesExplain the health consequences resulting from anorexia and bulimia nervosa

Subject:
Psychology
Social Science
Material Type:
Module
Date Added:
07/10/2017
A new herbal formulation shows demonstrated clinical efficacy and safety in promoting weight loss
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A new clinical trial has shown promising results for those trying to shed excess pounds: researchers have zeroed in on a combination of herbal extracts that can significantly increase weight loss under the right circumstances. The news could mean better health for the more than 1 billion people who are overweight or obese worldwide. Traditional pharmaceutical and surgical options for weight management are expensive and often associated with adverse effects. The herbal formulation – composed of extracts from three common culinary spices used in Indian cooking – was developed as a high-quality natural alternative. The combination tackles excess body weight through a multi-layered approach, by both preventing fat cells from maturing and boosting existing fat break down. To determine the safety and efficacy of the extracts, researchers performed a randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019