Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe the importance of fungi to the balance of the environmentSummarize the role of fungi in food and beverage preparationDescribe the importance of fungi in the chemical and pharmaceutical industriesDiscuss the role of fungi as model organisms

By the end of this section, you will be able to:Define genomicsDescribe genetic and physical mapsDescribe genomic mapping methods

By the end of this section, you will be able to:Describe three types of sequencingDefine whole-genome sequencing

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"During epithelial-mesenchymal transition (EMT), epithelial cells lose their polarity and their cell-cell connections to become mobile, in part via transcription factor (TF) activation. EMT and its reverse process, MET, are critical for tissue development in embryos, and EMT enables wound healing during adulthood, but EMT is also how cancer cells metastasize. Live imaging of animal embryos can yield important insights into these key processes. For example, FGF and actomyosin have been found to regulate intercellular adherens junction (AJ) remodeling during EMT in fruit flies. In addition, in zebrafish embryos, the planar cell polarity (PCP) protein pk1 ensures proper EMT of neural crest cells (NCCs), and cadherin 6 ultimately regulates NCC migration..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Interactions among probiotics, resident gut microbes and host factors affect probiotic engraftment and the resulting therapeutic effects. These interactions depend on gut-adaptive evolution of the probiotic strains, but the underlying processes—and their differences among host species—are unclear. In addition, the evolutionary effects of probiotics on native gut microbes are not well characterized. A recent genomics study examined the evolution and effects of the probiotic Lactiplantibacillus plantarum HNU082 (Lp082) in the human, mouse, and zebrafish gut. In all three species, Lp082 acquired single-nucleotide mutations. In vitro, the gut-adapted strains exhibited improved fitness related to carbohydrate utilization and acid tolerance and remained genetically stable for three months. In the human and mouse gut, Lp082 engraftment increased the numbers of mutations of the resident gut microbiota (GM) by 10- to 70-fold..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.