This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Kidney transplant patients currently require life-long treatment with immunosuppressive drugs to prevent their body from rejecting the transplanted organ. Immunosuppression can have side effects such as an increased risk of infections or developing comorbidities such as new onset diabetes or certain malignancies. Other side effects are related to the drugs’ toxicity, such as kidney damage, ultimately leading to a return to dialysis or need for re-transplant. A clinical trial, TRANSFORM, was carried out to test a new immunosuppressive regimen consisting of everolimus plus low-dose CNI, versus the current standard-of-care regimen: mycophenolic acid plus the standard, higher dose of CNI. The two-year results of this trial showed that the combination of everolimus plus low CNI had a similar ability to prevent kidney rejection or severe kidney impairment as the current standard-of-care regimen..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Applied Science
- Health, Medicine and Nursing
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 10/10/2019
