Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe the behavior of chromosomes during meiosisDescribe cellular events during meiosisExplain the differences between meiosis and mitosisExplain the mechanisms within meiosis that generate genetic variation among the products of meiosis

By the end of this section, you will be able to:Describe the behavior of chromosomes during meiosisDescribe cellular events during meiosisExplain the differences between meiosis and mitosisExplain the mechanisms within meiosis that generate genetic variation among the products of meiosis

By the end of this section, you will be able to:Describe the three stages of interphaseDiscuss the behavior of chromosomes during karyokinesisExplain how the cytoplasmic content is divided during cytokinesisDefine the quiescent G0 phase

By the end of this section, you will be able to:Describe the three stages of interphaseDiscuss the behavior of chromosomes during karyokinesisExplain how the cytoplasmic content is divided during cytokinesisDefine the quiescent G0 phase

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Critical defects that compromise the nucleus during cell division could be the basis for the age-accelerating effects of people living with progeria. Hutchinson-Gilford progeria syndrome is a genetic disorder that causes premature aging. Affecting one in 8 million newborns worldwide, the disorder is extremely rare—and fatal. The rapid aging of the cardiovascular system causes death due to heart attack or stroke in patients by their mid-teens. Progeria is caused by a tiny point mutation in the lamin A gene. This gene is responsible for producing structural proteins called lamins, which form the scaffolding that holds the cell nucleus together. The mutated form of prelamin A called progerin destabilizes the cell nucleus—the genetic control center of cells. The result is the fast-aging effects observed in progeria. But the link from gene mutation to physical disorder has remained a mystery. Previous studies have looked only at models of progeria, not at actual patient cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.