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Combining single-cell genomics and metagenomics to improve assembly in complex microbial communities
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"High-quality reference genomes are needed to understand the physiology and function of uncultured microbes in complex ecosystems. Metagenomics has been an incredibly useful tool for studying microbial communities, but assigning sequence assemblies accurately to genomes is difficult in microbial species or strains that lack a reference genome. These 'consensus genomes' have lower resolution than those generated from cultured isolates. Combining single-cell genomics with metagenomics may allow us to overcome these methodological weaknesses. Thus, researchers recently developed a framework called SMAGLinker, which integrates single-cell genomes from microfluidic droplets and uses them as guides for metagenome assembly. Compared to metagenomics alone, SMAGLinker showed more precise contig binning and higher recovery rates of rRNA and plasmids in a mock microbial community. In human gut and skin microbiota samples, SMAGLinker returned more genomes than the conventional metagenomics frameworks..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/13/2021
Elementary Science and Integrated Subjects - TEMPLATE
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CC BY
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Template developed by the Washington Office of Superintendent of Public Instruction (OSPI) ClimeTime grantees.This format is designed to be an example of how to develop a coherent lesson or suite of lessons that integrate other content areas such as English Language Arts, Mathematics and other subjects into science learning for students.

Subject:
Environmental Science
Life Science
Material Type:
Teaching/Learning Strategy
Author:
Barbara Soots
Ellen Ebert
Georgia Boatman
Kimberley Astle
Washington OSPI OER Project
Date Added:
07/21/2020
EmpoweredOER
Conditional Remix & Share Permitted
CC BY-NC-SA
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A set of tools and concrete examples to guide users through creating and evaluating OER with equity principles front of mind. EmpoweredOER adapts the BranchED Equity Rubric for OER Evaluation to expand on concepts with practical examples and suggestions and contextualises them for the Australian audience.

Subject:
Applied Science
Information Science
Material Type:
Teaching/Learning Strategy
Author:
Ash Barber
Date Added:
03/28/2024
NIST Artificial Intelligence Risk Management Framework
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Public Domain
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In collaboration with the private and public sectors, the National Institute for Standards and Technology (NIST) has developed a framework to better manage risks to individuals, organizations, and society associated with artificial intelligence (AI). The NIST AI Risk Management Framework (AI RMF) is intended for voluntary use and to improve the ability to incorporate trustworthiness considerations into the design, development, use, and evaluation of AI products, services, and systems.

Subject:
Technology
Material Type:
Reading
Author:
Rebecca Henderson
Date Added:
03/02/2024
OER-UCLouvain: A Framework to Understand, Analyse and Describe Online and Open Education in Higher Education
Only Sharing Permitted
CC BY-NC-ND
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This paper addresses online and open education. It presents a simple, yet comprehensive framework that can be adopted by any higher education institution in seek of: (1) clarification of terms and concepts related to online and open education, (2) awareness of issues and challenges to set up strategies for online or open learning, (3) informed choices and their impacts on operationalization actions, from an institutional point of view, (4) perspectives on crucial issues, such as mobility, that HEI faces in a context of internationalization, (5) awareness of policymakers and teachers on what open and online education is.
Paper Citation : Jacqmot, C.; Docq, F. and Deville, Y. (2020). A Framework to Understand, Analyse and Describe Online and Open Education in Higher Education.In Proceedings of the 12th International Conference on Computer Supported Education - Volume 1: CSEDU, ISBN 978-989-758-417-6, pages 458-465. DOI: 10.5220/0009470704580465

Subject:
Education
Educational Technology
Material Type:
Primary Source
Author:
Deville Yves
Docq Fran Oise
Jacqmot Christine
Date Added:
07/01/2020
Phylogenetic Core Groups: In search of a consistent methodological framework
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Although they’re microscopically small, microbes have critical effects on the world around them. The development of new technologies such as next-generation sequencing (NGS) has enabled scientists to examine what shapes microbial communities in the wild. A novel concept, Phylogenetic Core Groups (PCGs), aims to search for a taxonomic classification revealing the selective forces imposed by the environment, hence, complementing traditional classification methods. But because microbial communities are sensitive to environmental fluctuations and we observe only a small fraction of these communities, it is difficult to disentangle these selective forces from community composition only. A new study proposes an improved conceptual framework to refine the determination of PCGs. Starting with a regional pool of microbial species, scientists can observe changes in the community composition and relate these changes to environmental variables. Determining the relative contribution of stochastic vs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/15/2021