Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe the structure of eukaryotic cellsCompare animal cells with plant cellsState the role of the plasma membraneSummarize the functions of the major cell organelles

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Chloroplasts harness sunlight to power all the processes that help plants grow. Like engines, they must carefully balance their fuel to run efficiently. In plants, that’s the ratio of ATP to NADPH, two forms of fuel produced by photosynthesis. But scientists have long known that ATP/NADPH ratios in chloroplasts fall short of the value required for plants to turn CO₂ into sugars. To find out how plants overcome this imbalance, researchers tracked ATP in Arabidopsis plants in real time using a fluorescent protein sensor. They found that immature chloroplasts in young seedlings imported cytosolic ATP for chloroplast biogenesis, using an abundance of ATP transporter proteins to do the job, but mature chloroplasts downregulated these transporters to minimize ATP importation. Instead of importing ATP to maintain fuel balance, chloroplasts exported NADPH in the form of malate..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The blood–retinal barrier is a collection of tightly packed cells that keeps harmful substances from entering the retina. These cells include retinal microvascular endothelial cells, RMECs. RMEC dysfunction contributes to certain inflammatory eye diseases, including diabetic retinopathy, uveitis, and age-related macular degeneration. A recent study examined the effects of one emerging cause of this dysfunction: the leakage of mitochondrial DNA into the cytosol. Pathological stimuli, including hydrogen peroxide (H2O2), high glucose (HG), and liposaccharide (LPS), caused mitochondrial DNA to leak out of RMECs from rats through a process known as mitochondrial permeability transition pore opening. Leaked mitochondrial DNA regulated the expression of the signaling molecule cGAS. In turn, cGAS stimulated the expression of the pro-inflammatory molecules CCL4, CXCL10, and IFNB1 and transcription factor IRF1..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The human protein Tid-1 sits at the nexus of many key cellular processes and signaling pathways. These processes include cellular proliferation, growth, survival, aging, apoptosis, and even movement. Tid-1 is a member of the heat shock protein 40 family and helps other proteins fold correctly after translation or refold after a damaging stress event. Dysregulated Tid-1 behavior is involved in numerous human diseases including cancers, cardiomyopathies, and neurodegenerative disorders. Given its wide influence within the cell, Tid-1 could be a key biomarker or even therapeutic target for these diseases, but to leverage Tid-1 effectively, researchers need to understand its functionality in detail. To this end, a team of scientists consolidated the current research on human Tid-1. They found that Tid-1’s protein-protein interactions corresponded to its roles in various diseases and provide insight into how Tid-1 affects pathogenic developments..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.