This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular …
This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.
Techniques for the design and analysis of efficient algorithms, emphasizing methods useful …
Techniques for the design and analysis of efficient algorithms, emphasizing methods useful in practice. Topics include sorting; search trees, heaps, and hashing; divide-and-conquer; dynamic programming; greedy algorithms; amortized analysis; graph algorithms; and shortest paths. Advanced topics may include network flow, computational geometry, number-theoretic algorithms, polynomial and matrix calculations, caching, and parallel computing.
This subject describes and illustrates computational approaches to solving problems in systems …
This subject describes and illustrates computational approaches to solving problems in systems biology. A series of case-studies will be explored that demonstrate how an effective match between the statement of a biological problem and the selection of an appropriate algorithm or computational technique can lead to fundamental advances. The subject will cover several discrete and numerical algorithms used in simulation, feature extraction, and optimization for molecular, network, and systems models in biology.
This is a seminar based on research literature. Papers covered are selected …
This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments. The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB Ph.D. program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology.
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