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Genetic Variation Associated with Tamoxifen Effectiveness in American Indians and Alaska Natives with Breast Cancer
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Research has identified remarkably effective treatments for breast cancer But translation of these results to all patients requires pharmacogenetic research using diverse patient populations Although tamoxifen has been used to reduce the risk of breast cancer recurrence for the past 40 years Little is known about how well the drug works in American Indian and Alaska Native (AIAN) people A recent study focused on genetic variants of the cytochrome P450 gene CYP2D6, which is critical for tamoxifen activation Looking at AIAN participants in Alaska and Montana they identified common CYP2D6 variants in these populations that may affect tamoxifen metabolism Patients with these variants may not respond well to tamoxifen treatment and may benefit from alternative therapies This study highlights the key role of CYP2D6-mediated metabolism in tamoxifen response and suggests that considering genetic variation in diverse populations can help to improve the efficacy of breast cancer treatment We thank women from the Confed.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
06/23/2020
Genetically Modified Insect
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CC BY
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The January 2012 issue of PLOS Neglected Tropical Diseases presented an Editorial, a Viewpoint, and two accompanying Expert Commentaries that focussed on the application of genetically modified (GM) insects for control of animal and plant diseases. These articles describe the technological advances these tools represent, the regulatory framework, and the societal dialogue that is necessary for their wide-scale application for disease control. Here, we have assembled a collection of articles published in the PLOS journals that describe the technical and applied aspects of GM insects. We also included articles that are not strictly GM, but aim to modify the disease transmission traits of insects through the use of symbiotic microbes.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Data Set
Primary Source
Provider:
Public Library of Science
Provider Set:
Medicine and Health Sciences
Date Added:
04/07/2016
Genetic mutations in BRCA or DNA-repair genes appear to favor longer survival in patients with pancreatic cancer
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Pancreatic cancer is the fourth leading cause of cancer death among men and women and carries a poor prognosis; the percentage of patients living five years after diagnosis is just 5 to 10%. But certain patients with pancreatic cancer could fare better than others. A new study suggests that patients with a deficiency in genes responsible for responding to DNA damage could experience significantly superior outcomes compared with other patients following platinum-based chemotherapy. The findings support broader testing for germline mutations in patients with pancreatic cancer, as certain mutations could enhance the effects of anticancer therapeutics. The authors of the study reviewed medical records and genetic testing results to identify patients with pancreatic cancer who harbored mutations in DNA-damage response genes, including the breast cancer genes BRCA1 and 2. These genes help repair DNA breaks that can lead to cancer and uncontrolled tumor growth..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/23/2020
Genomics, Computing, Economics, and Society
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CC BY-NC-SA
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This course will focus on understanding aspects of modern technology displaying exponential growth curves and the impact on global quality of life through a weekly updated class project integrating knowledge and providing practical tools for political and business decision-making concerning new aspects of bioengineering, personalized medicine, genetically modified organisms, and stem cells. Interplays of economic, ethical, ecological, and biophysical modeling will be explored through multi-disciplinary teams of students, and individual brief reports.

Subject:
Applied Science
Biology
Economics
Health, Medicine and Nursing
Life Science
Social Science
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Church, George
Douglas, Shawn
Wait, Alexander
Zucker, Jeremy
Date Added:
09/01/2005
Getting Ready for Work-Integrated Learning
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CC BY-NC
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Short Description:
This resource was developed for all post-secondary students preparing for or wanting to learn more about work readiness for work-integrated learning (WIL) and entering the workforce. It covers topics including Indigenous Peoples, communities, and cultural safety; self-management; career goals; workplace essential skills; interpersonal and communication skills; workplace safety; and more. In addition, each chapter includes interactive H5P student activities for you to reinforce and self-assess your learning.

Word Count: 57513

ISBN: 978-1-77420-175-6

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Subject:
Applied Science
Business and Communication
Career and Technical Education
Communication
Health, Medicine and Nursing
Management
Material Type:
Textbook
Provider:
BCcampus
Date Added:
09/07/2022
Give me a hand! Bioengineering for Prosthetic Limbs
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CC BY-NC-SA
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 Students extend their knowledge of the skeletal system to biomedical engineering design, specifically the concept of artificial limbs and joints. Students relate the skeleton as a structural system, focusing on the hand as structural necessity. They learn about the design considerations involved in the creation of artificial limbs, including materials. This lesson plan was developed for emergent bilingual students who are intermediate or advanced in their English language development skills. This lesson is adapted from the following resources, "Engineering Bones" and "Prosthetic Party," on the TeachEngineering Digital Library: https://www.teachengineering.org/lessons/view/cub_biomed_lesson01, https://www.teachengineering.org/activities/view/cub_biomed_lesson01_activity1

Subject:
Anatomy/Physiology
Engineering
Health, Medicine and Nursing
Language Education (ESL)
Material Type:
Activity/Lab
Assessment
Diagram/Illustration
Interactive
Lesson
Lesson Plan
Author:
Paulette Rubio
Oregon Open Learning
Date Added:
06/14/2022
Glaucoma (Spanish)
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This patient education program discusses glaucoma including the anatomy of the eye, types of glaucoma, symptoms and risks, diagnosis, treatment options, and surgery. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
National Library of Medicine
Provider Set:
H.E.A.L.
Date Added:
11/17/2003
Global Enterprise for Micro-Mechanics and Molecular Medicine (GEM4)
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CC BY-NC-SA
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GEM4 Vision
GEM4 has brought together researchers and professionals in major institutions across the globe with distinctly different, but complementary, expertise and facilities to address significant problems at the intersections of select topics of engineering, life sciences, technology, medicine and public health.
GEM4 creates new models for interactions across scientific disciplinary boundaries whereby problems spanning the range of fundamental science to clinical studies and public health can be addressed on a global scale through strategic international partnerships.
Through initial focus areas in cell and molecular biomechanics, and environmental health, in the context of select human diseases, GEM4 creates a global forum for the definition and exploration of grand challenges and scientific studies, for the cross-fertilization of ideas among engineers, life scientists and medical professionals, and for the development of novel educational tools.
GEM4 Activities
GEM4 enables the brokering of engineers, life scientists and medical professionals with shared facilities and joint students and post-doctoral fellows to tackle major problems in the context of human health and diseases that call for state-of-the-art experimental and computational tools in cell and molecular mechanics, biology and medicine. Broad examples of problems addressed include:

infectious diseases such as malaria,
cancer,
cardiovascular diseases,
biomechanical origins of inflammation.

In each of these areas, the initial emphasis has included (but will not be limited to) molecular, subcellular and cellular mechanics applied to biomedicine, where a single investigator or institution is not likely to have the full spectrum of expertise, infrastructure or resources available to cover fundamental molecular science all the way to clinical studies and societal implications. Currently, twelve institutions in North America, Europe and Asia participate in this effort as Core institutions, focusing on mechanistic studies, as well as novel methods for diagnostics, vaccines or drug development and delivery.
Funds have been raised to provide a structure for coordinated studies from major organizations under the umbrella of GEM4. These funds are being used for:

organization of major symposia/conferences specifically targeted at the theme areas of the initiative,
training grants for student fellowships for the partner institutions,
summer schools to develop teaching materials,
the exchange of students and researchers,
operations of a central secretariat for handling the administrative and infrastructure details for such interactions,
maintenance of a web site for dissemination of information.

GEM4 Online

Subject:
Applied Science
Biology
Engineering
Health, Medicine and Nursing
Life Science
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Kamm, Roger
Date Added:
06/01/2006
Global Health: Crash Course Public Health #9
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Some Rights Reserved
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Disease doesn’t care about national borders. The pathogen hopping the red eye from Berlin to Boston doesn’t need a passport. So, in order to be proactive about protecting our health, we need to think globally. In this episode of Crash Course Public Health, we’re traveling around the world to look struggles and triumphs of public health on a global scale.

Chapters:
Introduction to Global Health
The WHO
Communicable Disease
Non-communicable Disease
Foreign Aid
Economic Inequality
Review & Credits
Credits

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
Complexly
Provider Set:
Crash Course Public Health
Date Added:
09/28/2022
Global Health Informatics to Improve Quality of Care
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CC BY-NC-SA
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This course will explore innovations in information systems for health care delivery in developing countries, and focus not only on the importance of technology, but also on broader issues necessary for its success, such as quality improvement, project management, and leadership skills. 
This course is targeted toward individuals interested in designing or implementing a health information and communication technology (ICT) solution in the developing world. Implementing a health information technology project requires multidisciplinary teams. Thus, with this course, we hope to bring together individuals from a variety of disciplines—computer science, medicine, engineering, public health, policy, and business.
What you’ll learn:

Global health burden
Design thinking
Health informatics
Software development process
Evaluation and monitoring

This course is part of the Open Learning Library, which is free to use. You have the option to sign up and enroll in the course if you want to track your progress, or you can view and use all the materials without enrolling.

Subject:
Applied Science
Business and Communication
Computer Science
Engineering
Health, Medicine and Nursing
Management
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Celi, Leo
Paik, Ken
Sebastián Osorio, Juan
Date Added:
02/01/2020
Global Health Innovation: Delivering Targeted Advice to an Organization in the Field
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CC BY-NC-SA
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In this three-day workshop, students will get a broad introduction to global health issues. We will look at one particular non-governmental organization in India that works to improve health across the lifespan by empowering existing community resources to provide appropriate physical, psychological and social therapies, focusing on child development, adolescent and youth health, mental health, and chronic disease. This workshop equips student to explore novel ideas and technologies with an inspiring and ground-breaking Indian NGO.
Fulfills the Sloan Innovation Period (SIP) elective requirement. SIP occurs at the midpoint of each semester providing students with an intensive week of experiential leadership learning, as well as exposure to groundbreaking faculty work. It allows students to engage in intellectual exploration outside the classroom. SIP degree requirements include core courses in ethics and leadership as well as electives.

Subject:
Applied Science
Business and Communication
Health, Medicine and Nursing
Management
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Sastry, Anjali
Date Added:
02/01/2015
GlobalHealth Lab
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CC BY-NC-SA
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This course pairs faculty-mentored student teams with enterprises on the front lines of health care delivery in sub-Saharan Africa and South Asia. To tackle specific barriers identified by each partnering organization, the course is built around custom-designed projects in strategy, business model innovation, operations, marketing, and technology. Class sessions include interactive cases, practical exercises, and lively conversations with experts, all designed to support project work before, during, and after the intensive two-week onsite collaboration with entrepreneurs, leaders, staff, and stakeholders in the setting. Course assignments include a portfolio of host deliverable, a foundational toolkit designed to support each project, and a distillation of learning from the field.
Acknowledgements
Special thanks is given to Imperial Health Sciences, Unjani Clinic and L V Prasad Eye Institute for allowing their organizations to be featured in the sample student projects on this course site.

Subject:
Applied Science
Business and Communication
Health, Medicine and Nursing
Management
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Sastry, Anjali
Date Added:
02/01/2013
A Global View of HIV Infection
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CC BY-NC-SA
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Title: A Global View of HIV InfectionCourse of Origin: Population Change and Public HealthKeywords: aids, disease, global, hiv, illness, infection, map, outbreak, spread, transmission, worldTopic Areas: Adolescent Health, Global Health, HIV/AIDS, Infectious DiseaseCitation Format: "A Global View of HIV Infection" from Population Change and Public Health. Copyright © Johns Hopkins Bloomberg School of Public Health. Creative Commons BY-NC-SA.

Subject:
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Author:
Ira Gooding
Date Added:
08/27/2020
Global Women's Issues: Women in the World Today, extended version
Unrestricted Use
Public Domain
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Short Description:
We cannot solve global challenges unless women participate fully in efforts to find solutions. Female participation in the private sector is a crucial economic driver for societies worldwide. Economic security benefits every facet of a woman’s life, with positive effects on the health, education and vitality of families. Learn about women who are changing their societies for the better. This extended version of Global Women’s Issues: Women in the World Today includes, for each chapter, a summary, key words, multiple choice questions, discussion questions, essay questions, and a list of additional resources.

Long Description:
Global Women’s Issues: Women in the World Today is based on the twelve critical areas of concern identified in the Beijing Declaration and Platform for Action at the Fourth World Conference on Women in Beijing in 1995. The persistent and increasing burden of poverty on women. Inequalities and inadequacies in and unequal access to education and training. Inequalities and inadequacies in and unequal access to health care and related services. Violence against women. The effects of armed or other kinds of conflict on women, including those living under foreign occupation. Inequality in economic structures and policies, in all forms of productive activities and in access to resources. Inequality between men and women in the sharing of power and decision-making at all levels Insufficient mechanisms at all levels to promote the advancement of women. Lack of respect for and inadequate promotion and protection of the human rights of women. Stereotyping of women and inequality in women’s access to and participation in all communication systems, especially in the media. Gender inequalities in the management of natural resources and in the safeguarding of the environment. Persistent discrimination against and violation of the rights of the girl child

Word Count: 65077

ISBN: 978-1-622-39925-3

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Subject:
Applied Science
Gender and Sexuality Studies
Health, Medicine and Nursing
Law
Social Science
Material Type:
Textbook
Provider:
United States Department of State
Provider Set:
Bureau of International Information Programs
Date Added:
01/01/2012
Glucose Tolerance Test handout for Medical Office and Laboratory Assistants (GTT McCuaig.pdf)
Only Sharing Permitted
CC BY-NC-ND
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A five-page illustrated handout for Medical Office and Laboratory Assistants that explains:
- What a Glucose Tolerance Test (GTT) is
- Why monitoring diabetes is important
- What equipment is necessary for a proper GTT
- How to prepare the patient for a GTT
- How to conduct the GTT
- When blood and urine should be collected
- What could interfere with the test results
- Possible complications from the test
- When to alert the doctor and nurse
- What the test results mean
- How to report the test results

Subject:
Anatomy/Physiology
Applied Science
Career and Technical Education
Education
Health, Medicine and Nursing
Higher Education
Life Science
Material Type:
Diagram/Illustration
Reading
Student Guide
Teaching/Learning Strategy
Author:
Theresa McCuaig
Date Added:
03/21/2022
Goal Setting for Today and Beyond/ Health Class
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CC BY-SA
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Objective: The student will list 2 short term goals and two long term goals using the SMARTER method.Teacher Lecture:Key Terms:Short term goals: A short-term goal is something you want to do in the near future. The near future can mean today, this week, this month, or even this year.Long term Goals: Goals that take a long time to achieve are called long-term goals.SMARTER goal setting method: Specific, Measurable, Attainable, Relevant and Timely, Evaluation and Readjustmant.Video: Accomplish Your Dreams in 2017Video provided by Heather. https://www.youtube.com/channel/UCVzgz47HsbyUA1S9pp79VUg/aboutCreative Commons — Attribution-ShareAlike 3.0 Unported— CC BY-SA 3.0    Students will watch the 8 minute video to reinforce the instructors lecture.   

Subject:
Health, Medicine and Nursing
Material Type:
Lesson Plan
Author:
Randy Christmas
Date Added:
03/22/2018