The popular economist Walter E. Williams was one of the most prominent libertarian commentators on issues of race, poverty, and prosperity, spreading his message through a weekly syndicated column, scholarly publications, and a variety of media appearances. Born and raised in the Philadelphia projects, Williams overcame personal and political barriers on his journey from blue-collar kid working odd jobs to a distinguished writer and professor. Prolific and provocative, Williams appealed to both specialists and lay people, and his great love was teaching economics. Throughout his life, a network of devoted friends, family, mentors, and colleagues made his success possible.

The Woodson Center's Black History and Excellence curriculum is based on the Woodson Principles and tells the stories of Black Americans whose tenacity and resilience enabled them to overcome adversity and make invaluable contributions to our country. It also teaches character and decision-making skills that equip students to take charge of their futures. These lessons in Black American excellence are free and publicly available for all.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Microbiomes are more than just prokaryotes and viruses; they also contain important eukaryotes, including fungi and protists. However, eukaryotes are difficult to study using ‘shotgun’ metagenomics, as their signal is often overwhelmed by the prokaryotes. Some methods use eukaryote-specific marker genes, but they can’t detect eukaryotes that aren’t in the reference marker gene set, and such methods are not compatible with web-based tools for downstream analysis. But CORRAL (Clustering Of Related Reference ALignments) is designed to close those gaps. CORRAL identifies eukaryotes in metagenomic data based on alignments to eukaryote-specific marker genes and Markov clustering. It can detect microbial eukaryotes that are not included in the marker gene reference set. The process is even automated and can be carried out at scale. A recent paper demonstrates CORRAL’s sensitivity and accuracy with simulated datasets, mock community standards, and human microbiome datasets..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Non-small cell lung cancer (NSCLC), the most common lung cancer, is also the most lethal cancer worldwide. The protein CPNE1 has been found to promote NSCLC, but it’s not clear how. To find out, researchers recently manipulated CPNE1 expression in NSCLC cells in vitro. CPNE1 overexpression activated cancer progression processes, such as proliferation, migration, invasion, and MET signaling, while CPNE1 silencing produced the opposite effects. Silencing RACK1, another cancer-driving protein, suppressed the tumor formation and MET signaling activation caused by CPNE1 overexpression, confirming that RACK1 mediates CPNE1-induced cancer progression and suggesting that MET is involved. Since CPNE1 is also believed to activate EGFR signaling, the researchers tested the effects of both MET and EGFR inhibition on NSCLC tumors in mice..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Creative Commons is an open license that actually works with Copyright with a slant to copyleft.

Barrangou and a team of researchers at Danisco first experimentally demonstrated the technique of CRISPR (Clusters of Regularly Interspaced Short Palindromic Repeats). To fight off the infecting bacteriophages, the bacterial immume systems (CRISPR-Cas9) specifically target genomic sequences. Cas9 is an enzyme that cuts DNA which is associated with the specialized stretches of CRISPR DNA.
This figure clearly depicts how the bacterium protects itself from the infecting viruses (bacteriophages).

C.T. Hibino, half-length portrait, standing, facing front, holding paintbrush and palette, in front of large painting. Original neg. no.: LC-A351-3-M-40-B. Title transcribed from Ansel Adams' caption on verso of print. Gift; Ansel Adams; 1965-1968. Forms part of: Manzanar War Relocation Center photographs.

C.T. Hibino, artist, three-quarter length portrait, standing, facing front, holding paintbrush and palette, in front of large painting. Title transcribed from Ansel Adams' caption on verso of print. Original neg. no.: LC-A351-3-M-40-A. Gift; Ansel Adams; 1965-1968. Forms part of: Manzanar War Relocation Center photographs.

The cecum is a blind ending diverticulum of the large intestine and it exists at the junction of the ileum and the ascending colon. Its size and physiological importance varies between species. It is a site of microbial fermentation, absorption and transportation.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The ubiquitous second messenger calcium (Ca2+) interacts with numerous cellular proteins to regulate physiological processes. Ca2+ also participates in a variety of diseases, including hepatitis B virus (HBV) infection. HBV infection is a major cause of fibrosis, cirrhosis, and hepatocellular carcinoma. Recent studies have demonstrated that HBV infection elevates levels of intracellular Ca2+ and this elevation is primarily dependent on the HBV protein HBX. The activation of Ca2+ signaling contributes to viral replication in HBV-infected cells. The importance of Ca2+ signaling in HBV infection makes controlling intracellular Ca2+ a promising therapeutic target. Early studies have suggested that binding cytosolic Ca2+ or inhibiting Ca2+ channels reduces viral replication, but current research is largely derived from in vitro cellular models and needs to be confirmed in animal models and human patients..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

An advertising calendar for a lithographic printing firm, decorated with Unionist symbols and motifs. The calendar for 1863 and the first 6 months of 1864 is surrounded with an elaborate framework of floral and acanthus ornament, surmounted by the figure of Columbia or Liberty. The figure is closely based on Thomas Crawford's statue of Freedom on the U.S. Capitol. She stands holding shield and sword, and wearing a robe emblazoned with stars and an eagle headdress with a crown of stars. At her right are symbols of progress, industry, and culture: a locomotive, a plough with a sheaf of grain, a statue, and a printing press. At her left are artifacts of war such as tents, cannons, arms, and an eagle. Flanking the calendar itself are two vignettes. On the left is a peacetime scene, with a farmer holding a scythe as two field hands harvest grain behind him. On the right a soldier with a rifle stands before a battlefield. Two putti appear in the acanthus scrolls below.|Ehrgott, Forbriger & Co. Lithographers, Cincinnati.|Entered . . . 1862 by Ehrgott, Forbriger & Co. . . . Ohio.|The Library's copy of the calendar was deposited for copyright on January 3, 1863.|Title appears as it is written on the item.|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1862-17.

An advertising calendar for a lithographic printer, with various patriotic motifs and a subtle commentary on the Emancipation Proclamation. The calendar, for 1863, is set within an elaborate architectural framework. The whole is draped with an enormous flag which hangs down from an enthroned Columbia at top. Columbia sits holding a sword and shield, an eagle on her left, and a globe and the Constitution at her feet. Further left are a plough, scythe, and wheat sheaves. On the right appear symbols of progress and industry including a telescope, locomotive, anvil and hammer, millstone and gear wheel, and bales and barrels of goods. On the middle register are symbols of the arts, sciences, and learning, including an easel painting, palette and brushes, musical instruments, books, urns, and a tapestry. On the far left a seaman mans a cannon before a backdrop of sails and smokestacks. On the right an infantryman stands guard with his dog before an encampment. At the bottom are two scenes. The scene on the left shows three black children and a white child, who watches idly as one of the three stands on a cotton bale and whitewashes over a placard reading "1862." Another black child, kneeling on a crude wooden block with chains attached to it (an allusion to slavery), holds the bucket of whitewash, and the third blows soap bubbles. In the scene on the right the roles are reversed: as the white child works, the three black children are idle. Standing on a pedestal labeled "Emancipation," the white boy inscribes the date "1863" on a panel. He holds a portfolio under his arm. A black child sits on a classical cornice at left, holding a small bucket of paint while one of his companions reclines on the ground. The third black child sits fiddling on a fallen column nearby. A small hourglass appears in a vignette below the calendar. |Ehrgott, Forbriger & Co. Lith. Cincinnati.|Entered . . . 1862 by Ehrgott, Forbriger & Co. . . . Ohio.|The Library's impression of the calendar was deposited for copyright on January 3, 1863. |Title appears as it is written on the item.|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1862-18.

Group of girls standing in line formation, each one reaching both of her arms straight out to the side. Title transcribed from Ansel Adams' caption on verso of print. Original neg. no.: LC-A35-6-M-8. Gift; Ansel Adams; 1965-1968. Forms part of: Manzanar War Relocation Center photographs.

Group of young women standing in line formation, each one reaching both of her arms straight up from her shoulders. Title transcribed from Ansel Adams' caption on verso of print. Original neg. no.: LC-A35-6-M-7. Gift; Ansel Adams; 1965-1968. Forms part of: Manzanar War Relocation Center photographs.

Highlights from the past and present of California, from the rich online collections of the Library of Congress.

Title from item. Poster is text only, with "extract from a letter from the trenches." Wt.P.40 5,000.4/15. B515.

Once more the House of Representatives investigation of Treasury practices under the Van Buren administration in connection with the Swartwout embezzlement scandal. (See above nos. 1839-6 through -9.) The print must have appeared in January or February, after the House of Representatives voted to form its select investigative committee by ballot. Speaker of the House James K. Polk, perceived as a friend of the administration, was prevented by a Whig majority in the House from appointing the committee himself, as was customary. Here a kneeling, bespectacled Polk is berated by Satan (who could represent Van Buren). Satan: "What does this mean? How came you to let that Committee be chosen by ballot? Don't you know we're undone? Was it for this I made you Chancellor of the Exchequer? Did not you engage to do all our work? and manage the House for my interest? and here's that cursed [Whig Congressman Henry A.] Wise with his Committee breaking in to our Head Quarters! I'll cashier you!!" Polk: "Dread Sir! be not too wratful with your servant; I did my very best. You know I have not the influence I once had; I'm sure I turned & twisted & did all a man could. Pray try me but once more; See if I don't carry your Sub-Treasury Bill for you, & if that passes you know we are all made!" "Called to Account" is most probably by the same artist as "Symptoms of a Duel" (no. 1839-10).|Drawn by HD?|Entd . . . 1839 by H.R. Robinson.|Printed & publd. by H.R. Robinson, 52 Cortlandt & 11-1/2 Wall st. N. Y.|Title appears as it is written on the item.|Weitenkampf, p. 57.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1839-11.

Poster showing a soldier playing bagpipes, beside him a dog, with troops marching in the background. Title from item. Wt. 1725 20000 7/16 H.M.S.O.