Poster showing the Thrift Card and the War-Savings Certificate, and explaining each plan for incremental investment. Forms part of: Willard and Dorothy Straight Collection.

Poster showing a variety of people lined up at a window tended by Uncle Sam, beneath a sign "W.S.S. for sale here"; a little girl waves the American flag in the foreground. No. S-11.

Poster showing a variety of people lined up at a window tended by Uncle Sam, beneath a sign "W.S.S. for sale here"; a little girl waves the American flag in the foreground. No. S-11. Forms part of: Willard and Dorothy Straight Collection.

Poster shows a rear view of a soldier facing battlefield. Title from item. W.P. 6.

Poster shows Canadian soldiers in trucks driving over a road paved with war bonds. Title from item. W.P. No. 5.

Poster showing a table of investments and yields. Poster no. 14. Title from item.

Poster showing head-and-shoulders portrait of Woodrow Wilson and a quote from him. No. 8.

Poster showing a bulldog, and faces of men wearing a variety of military hats. Title from item. "Some club."

Poster showing a button with the Statue of Liberty and the motto, "I own a Liberty Bond." No. 10(?).

Poster showing Uncle Sam gesturing towards troops, ships, and planes around the Statue of Liberty. "Shall we be more tender with our dollars than with the lives of our sons", W.G. McAdoo, Secretary of the Treasury. No. 1.

This resource is a publishing of 64 drawn illustrations. The images were initially created for an art installation by Kellie Bornhoft (kelliebornhoft.com). The artist wishes to share the images under CC BY-NC 4.0 for educational and non-commercial use. The intention is to bring awareness to these endangered species. 

This art history video discussion examines "Justinian and His Attendants," 6th century, San Vitale, Ravenna.

Poster showing an older man with axe and rifle joining a battle. Issued by Czechoslovak Recruiting Office, Tribune Building, New York. Designed and printed at the School of Printing and Graphic Arts of Wentworth Institute, Boston, Mass., U.S.A. Wentworth poster no. 11.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Leukemia relapse after conventional treatments is difficult to treat and has high patient mortality. Relapse is driven by the reawakening of previously quiescent cancer cells. Traditional treatments are ineffective against quiescent cells, as they instead target rapidly dividing cells. A new study investigated a potential dual-target treatment, C212, in cell culture. C212 is a derivative of curcumin, a compound that has shown anticancer properties in previous research. C212 was effective against both growing and quiescent leukemia cells. C212 drives quiescent leukemia cells deeper into dormancy by increasing their exit threshold, and then kills these deep-quiescent cells. This differs from previous strategies that awaken quiescent cells to kill, which runs the risk of wakening treatment-resistant subpopulation of cells. Molecular docking and experimental analyses showed that C212 could bind to Hsp90 and interferes with its function..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Even with antibiotics, severe pneumonia can lead to sepsis and death. Researchers in Germany have now identified a promising new therapy that may improve outcomes. Reporting in the journal Anesthesiology, the scientists indicate that targeting C5a, a component of the body’s complement system, may be a novel adjunctive therapy for severe pneumonia. One reason why patients don’t fare well with Streptococcus pneumoniae is that their highly activated immune system can damage tissue as it tries to clear the pathogen from the body. An important part of the body's first-line immune defense is the complement system, plasma proteins that patrol the body and coordinate with immune cells to kill invading bacteria. For example, when complement protein C5 is cleaved into C5a and C5b, C5b goes on to poke holes in bacteria. The smaller C5a is pro-inflammatory, attracting and activating neutrophils and making blood vessel walls more permeable to immune cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cancer cell growth depends on the production of new blood vessels by tumor endothelial cells in a process called angiogenesis. But the growing cancer cells produce large amounts of lactic acid as a byproduct of glucose breakdown. How tumor endothelial cells are able to survive in this toxic environment is unclear. In a recent study, researchers sought to uncover the mechanism of tumor endothelial cell survival in a lactic acid-rich tumor microenvironment. Using genetics and proteomics, they compared the RNA and protein levels of pH-regulating proteins in tumor endothelial cells to those in normal endothelial cells. They found that carbonic anhydrase 2 (CAII), an important pH regulator, was elevated in tumor endothelial cells, which was induced through the VEGF signaling pathway. Blocking CAII in tumor endothelial cells decreased cell survival in lactic acid conditions, and treating tumor-bearing mice with a CAII inhibitor had decreased lung metastasis..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Metabolic regulation is vital to maintaining energy balance throughout the body, and different cell types have different ways of maintaining this balance. CAMKK2 is an enzyme common to various cells that aids in breaking down glucose through cellular respiration, but the details of how CAMKK2 carries out that role in different cells remains unclear. To find out, researchers deleted the gene for CAMKK2 from human kidney and liver-derived cells. Deleting CAMKK2 significantly reduced cellular respiration in both cell types versus parental cells. However, isolated mitochondrial respiration increased in kidney cells but decreased in liver cells. Proteomic analysis traced this difference to translational and transcriptional changes in succinate dehydrogenase (SDH). SDH is the only enzyme complex that participates in both the Krebs cycle and electron transport chain. Removing or overexpressing SDH subunit B in CAMKK2-deleted cells confirmed the functional link between SDH and CAMKK2..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Survey of speech, language, and communication disorders for educators. Consideration of varied disorders that might be encountered in educational settings; application to children from culturally and linguistically diverse backgrounds.

Syllabus Description: This course is an overview of speech, language, and hearing disorders. It will investigate the impact of communication on children with developmental disabilities and enable non-specialists to work effectively with this population. Throughout this course, we will consider a range of problems (i.e. neurological and physiological disabilities), as well as applications to children from culturally and linguistically diverse backgrounds.