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Another mechanism for the initiation and progression of Parkinson’s disease?
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A recent study published in Acta Neuropathologica Communications has found a potential mechanism for the initiation and development of Parkinson’s disease and it appears red blood cells may be partly to blame. Parkinson’s is a chronic and progressive neurodegenerative disorder commonly associated with tremors, muscle stiffness, and impaired movement. While these symptoms are caused by the deterioration of nerve cells in the brain, the precise cause of the disease is still not fully understood. What is known is that the development of Parkinson’s is associated with the aggregation of toxic forms of a protein named alpha-synuclein (or alpha-syn, for short) in the brain. Recent evidence, however, suggests alpha-syn found in the blood can also be problematic and this has been implicated as a contributor to brain-cell breakdown..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019
Ansiedad en la era COVID-19: Estado, Rasgo y Resiliencia
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CC BY-NC-SA
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Esta investigación analiza los niveles de ansiedad-rasgo y ansiedad-estado, modificando una ansiedad-estado como un estado emocional inmediato, evolucionando en el tiempo. Mientras que la ansiedad rasgo se refiere a diferencias individuales relativamente estables en la ansiedad. Tuvo como objetivo determinar niveles de ansiedad estado - rasgo en tiempos de pandemia Covid-19 en trabajadores de Red de Salud Angaraes - Huancavelica, 2021. Metodología: investigación básica, nivel descriptivo, método analítico sintético, diseño no experimental, transaccional, descriptivo, técnica utilizada, encuesta, se utilizó Inventario Ansiedad Rasgo Estado (IDARE), se tuvo muestra de 110 trabajadores. Resultados: Concerniente a niveles de ansiedad estado, se evidencia nivel bajo 7,27%, nivel medio 41,82% y 50,91% nivel alto. Respecto a ansiedad rasgo, 6.36%, nivel bajo, 40,91 % nivel medio y el 52,73% nivel alto. Respecto al género para ansiedad estado, para femeninos 2.73% nivel bajo, 20.00% nivel medio y 30.91% nivel alto; para masculinos, 4,55% nivel bajo, 21,82% nivel medio y 20,00% nivel alto. De acuerdo con el género, ansiedad rasgo, femeninos presentan 1,82% nivel bajo, 20.00% nivel medio y 31,82% nivel alto. Género masculino presentan 4,55% nivel bajo, nivel medio 20,91% y 20,91% nivel alto. Respecto a edad, trabajadores de 21 a 30 años presentan ansiedad estado en nivel bajo (2,7%), 22,7% nivel medio, y 9,1% nivel alto; de 31 a 40 años 2,7% nivel bajo, nivel medio 13,6%, y 34,5% nivel alto. Conclusión: Los trabajadores de la Red de Salud Angaraes, presentan nivel alto de ansiedad estado 50,91%, respecto a ansiedad rasgo, presentan un nivel alto 52,73%.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Textbook
Provider:
Editorial Grupo AEA
Author:
Blas Oscar Sánchez-Ramos
Cesar Cipriano Zea-Montesino
Charo Jacqueline Jauregui-Sueldo
Olga Vicentina Pacovilca Alejo
Raúl Ureta-Jurado
Rodrigo Quispe-Rojas
Yda Flor Camposano-Córdova
Date Added:
01/31/2024
Antarctic Ice Movement: Part I
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Educational Use
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This video segment adapted from NOVA explains why ice sheets move. To find out how fast they move, scientists carve a tunnel through a glacier.

Subject:
Applied Science
Environmental Science
Material Type:
Activity/Lab
Diagram/Illustration
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
12/17/2005
Antarctica: A Challenging Work Day
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What happens when the ground under your feet is ice and it's moving? This video segment adapted from NOVA features some of the dangers faced by scientists conducting research in Antarctica.

Subject:
Applied Science
Environmental Science
Material Type:
Activity/Lab
Diagram/Illustration
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
12/17/2005
Antarctica: King of Cold
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CC BY-SA
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This article includes links to expository text for students in grades K-1, 2-3, and 4-5 about the climate differences between the Arctic and Antarctica.

Subject:
Applied Science
Environmental Science
Geoscience
Physical Science
Material Type:
Lesson Plan
Provider:
Ohio State University College of Education and Human Ecology
Provider Set:
Beyond Penguins and Polar Bears: An Online Magazine for K-5 Teachers
Author:
Stephen Whitt
Date Added:
10/17/2014
Anterolateral structure (ALS) injury is significant risk factor for grade 3 pivot shift in knees with acute ACL injuries
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Among patients undergoing ACL reconstruction surgery, a high-grade pivot shift before surgery is widely considered to confer an increased risk of graft rupture and persistent instability after surgery. But what are the risk factors for high-grade pivot shifts themselves? A new study published in The American Journal of Sports Medicine reports injury to anterolateral structures as the most important risk factor for high-grade pivot shifts in patients suffering ACL injuries. The pivot shift test is the most specific physical exam for diagnosing ACL injuries. The examiner applies inward pressure on the lateral thigh with one hand while internally rotating the lower leg as the knee is flexed from a fully extended position. The presence of a pivot shift is indicated by an abrupt forward shift of the tibia back to its normal anatomical position. This shift is graded between 1 and 3 according International Knee Documentation Committee criteria, with 1 and 2 considered low grade, and 3 considered high grade..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/23/2020
Anthrax (Spanish)
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This patient education program explains the causes and types of anthrax. It also reviews the symptoms, diagnosis, treatment, and prevention of anthrax through vaccination and awareness of bioterrorism. This resource is a MEDLINEplus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
National Library of Medicine
Provider Set:
H.E.A.L.
Date Added:
11/17/2003
The Anthropocene and the Near Future: Crash Course Big History #9
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In which John Green, Hank Green, and Emily Graslie teach you about the Anthropocene, an unofficial geological era that covers the last century or so, in which humanity has made massive progress. We've discovered the Higgs-Boson particle, and awesome electric cars, and amazing smartphones. So all this collective learning and progress has been good for everyone, right? Maybe not. We'll look at some of the pros and cons of all this "progress," including environmental impact, changes in the way people live and work, and political changes and wars that come along with the modern world. We've come a long way, but there's a long way to go. Crash Course will also take a look at what's going to happen in the near future. If we manage to make our way through the coming bottlenecks, we could be OK in coming centuries. Don't get too hopeful, though. The Sun will eventually die, and the Earth will be destroyed, and later the universe will eventually experience heat death. But we won't talk about those downers until next week.

Subject:
Applied Science
Environmental Science
History
Material Type:
Lecture
Provider:
Complexly
Provider Set:
Crash Course Big History
Date Added:
01/06/2015
Antibiotics, Toxins, and Protein Engineering
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CC BY-NC-SA
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The lethal poison Ricin (best known as a weapon of bioterrorism), Diphtheria toxin (the causative agent of a highly contagious bacterial disease), and the widely used antibiotic tetracycline have one thing in common: They specifically target the cell’s translational apparatus and disrupt protein synthesis.
In this course, we will explore the mechanisms of action of toxins and antibiotics, their roles in everyday medicine, and the emergence and spread of drug resistance. We will also discuss the identification of new drug targets and how we can manipulate the protein synthesis machinery to provide powerful tools for protein engineering and potential new treatments for patients with devastating diseases, such as cystic fibrosis and muscular dystrophy.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subject:
Applied Science
Biology
Engineering
Life Science
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Koehrer, Caroline
Sassanfar, Mandana
Date Added:
02/01/2007
Antimatter Matters
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Antimatter, the charge reversed equivalent of matter, has captured the imaginations of science fiction fans for years as a perfectly efficient form of energy. While normal matter consists of atoms with negatively charged electrons orbiting positively charged nuclei, antimatter consists of positively charged positrons orbiting negatively charged anti-nuclei. When antimatter and matter meet, both substances are annihilated, creating massive amounts of energy. Instances in which antimatter is portrayed in science fiction stories (such as Star Trek) are examined, including their purposes (fuel source, weapons, alternate universes) and properties. Students compare and contrast matter and antimatter, learn how antimatter can be used as a form of energy, and consider potential engineering applications for antimatter.

Subject:
Applied Science
Engineering
Physical Science
Physics
Space Science
Technology
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Anti-plagiarism and Citations
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CC BY
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Hope Scholar Library Workshop

Word Count: 22286

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Subject:
Applied Science
Information Science
Material Type:
Textbook
Date Added:
01/26/2024
Antiplatelet drugs might help, not harm, survivors of brain haemorrhage
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"More than one-third of people who’ve survived brain hemorrhage stop taking oral anti-blood-clotting drugs, like aspirin. Normally taken to prevent blood vessel blockage, so-called antiplatelet drugs increase the risk of bleeding in general. So they’re widely believed to increase the risk of brain hemorrhage happening again. But new research suggests that might not be the case. Researchers came to that conclusion following a randomized trial involving more than 500 survivors of brain hemorrhage in the UK. Participants were mostly men over the age of 70; all had a history of diseases that cause blockage of blood flow due to clotting but had stopped taking oral antiplatelet drugs after their brain hemorrhage. Researchers split those patients into two groups: half were encouraged to start antiplatelet drugs, and half were encouraged to stay off these drugs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/23/2019
Anya: Citizen Science in Siberia - Young Voices on Climate Change
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Citizen scientist Anya, an indigenous Siberian girl, witnesses the changes in her community as a result of climate change after working with Woods Hole scientist Max Holmes' research team aboard her father's ship. She gets involved in collecting water samples to learn, and teach her schoolmates about, global warming.

Subject:
Applied Science
Career and Technical Education
Environmental Science
Environmental Studies
Physical Science
Material Type:
Diagram/Illustration
Reading
Provider:
CLEAN: Climate Literacy and Energy Awareness Network
Provider Set:
CLEAN: Climate Literacy and Energy Awareness Network
Author:
Lynne Cherry
Young Voices for the Planet
Date Added:
05/15/2012
Análisis de poder estadístico y cálculo de tamaño de muestra en R: Guía práctica
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CC BY
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Esta guía práctica acompaña la serie de videos Poder estadístico y tamaño de muestra en R, de mi canal de YouTube Investigación Abierta, que recomiendo ver antes de leer este documento. Contiene una explicación general del análisis de poder estadístico y cálculo de tamaño de muestra, centrándose en el procedimiento para realizar análisis de poder y tamaños de muestra en jamovi y particularmente en R, usando los paquetes pwr (para diseños sencillos) y Superpower (para diseños factoriales más complejos). La sección dedicada a pwr está ampliamente basada en este video de Daniel S. Quintana (2019).

Subject:
Applied Science
Biology
Health, Medicine and Nursing
Life Science
Mathematics
Psychology
Social Science
Statistics and Probability
Material Type:
Reading
Author:
Juan David Leongómez
Date Added:
08/18/2020
Análisis y visualización de datos usando Python
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CC BY
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Python es un lenguaje de programación general que es útil para escribir scripts para trabajar con datos de manera efectiva y reproducible. Esta es una introducción a Python diseñada para participantes sin experiencia en programación. Estas lecciones pueden enseñarse en un día (~ 6 horas). Las lecciones empiezan con información básica sobre la sintaxis de Python, la interface de Jupyter Notebook, y continúan con cómo importar archivos CSV, usando el paquete Pandas para trabajar con DataFrames, cómo calcular la información resumen de un DataFrame, y una breve introducción en cómo crear visualizaciones. La última lección demuestra cómo trabajar con bases de datos directamente desde Python. Nota: los datos no han sido traducidos de la versión original en inglés, por lo que los nombres de variables se mantienen en inglés y los números de cada observación usan la sintaxis de habla inglesa (coma separador de miles y punto separador de decimales).

Subject:
Applied Science
Computer Science
Information Science
Mathematics
Measurement and Data
Material Type:
Module
Provider:
The Carpentries
Author:
Alejandra Gonzalez-Beltran
April Wright
Christopher Erdmann
Enric Escorsa O'Callaghan
Erin Becker
Fernando Garcia
Hely Salgado
Juan M. Barrios
Juan Martín Barrios
Katrin Leinweber
LUS24
Laura Angelone
Leonardo Ulises Spairani
Maxim Belkin
Miguel González
Nicolás Palopoli
Nohemi Huanca Nunez
Paula Andrea Martinez
Raniere Silva
Rayna Harris
Sarah Brown
Silvana Pereyra
Spencer Harris
Stephan Druskat
Trevor Keller
Wilson Lozano
chekos
monialo2000
rzayas
Date Added:
08/07/2020
Aplicacición de un Sistema Operativo de Tiempo Real (RTOS) en un robot Arduino
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CC BY-SA
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Trabajo Final para la cátedra Diseño de Sistemas de Tiempo Real. En este trabajo se muestra desde cómo armar el robot con las piezas compradas hasta cómo modificar y adaptar RTuinOS (un SO de Tiempo Real) para que funcione en nuestro Arduino.

Subject:
Applied Science
Computer Science
Material Type:
Lecture Notes
Author:
María Emilia Charnelli
Date Added:
11/07/2017
Aplicaciones y Teoría de Ingeniería de Microondas
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CC BY-SA
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El actual crecimiento de las comunicaciones inalámbricas, debido al incremento de las comunicaciones de voz, vídeo y consumo de datos está causando una creciente demanda de la cantidad de canales y el ancho de banda, esto, está impulsando a los sistemas transceptores de comunicación hacia frecuencias de microondas y de ondas milimétricas para satisfacer la demanda mundial de mayores velocidades de transmisión de banda ancha, los sistemas de comunicación de comunicación inalámbrica requiere también de n desarrollo a la par de esta demanda. La Teoría electromagnética proporciona la base para todos los circuitos de microondas que hizo posible los grandes avances logrados por el campo de microondas. Es importante entender que la teoría de campo de microondas es sólo una parte de la teoría del campo electromagnético en general.

Subject:
Applied Science
Engineering
Material Type:
Textbook
Provider:
Project LATIn: The Latin American Open Textbook Initiative
Author:
Ebert Gabriel San Román Castillo
Efraín Zenteno Bolaños
Lee Victoria Gonzales Fuentes
Manuel Gustavo Sotomayor Polar
Patricia Raquel Castillo Araníbar
Date Added:
11/29/2017
Apollo 11: The Writings on the Wall
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CC BY-NC
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Look in the Apollo 11 Command Module Columbia to observe and record some hand-written notes and markings in areas of the spacecraft that have been hidden from view for more than 40 years.

Subject:
Applied Science
Astronomy
Engineering
History
Physical Science
Material Type:
Activity/Lab
Provider:
National Air and Space Museum
Author:
National Air and Space Museum
Date Added:
10/05/2022
Apollo Inflight Exerciser
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CC BY-NC
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The American Space Program was experimenting with fitness in Space when a variable resistance rope friction device which was originally designed to lower people from a burning building.

Subject:
Applied Science
Engineering
Material Type:
Reading
Provider:
National Air and Space Museum
Author:
National Air and Space Museum
Date Added:
10/03/2022