We’ve already learned the basics of carbonyl chemistry and talked about how …
We’ve already learned the basics of carbonyl chemistry and talked about how we can synthesize aldehydes and ketones, but there’s still so much more to learn, like the role carbonyl groups play in reactions involving sedatives! In this episode of Crash Course Organic Chemistry we’re diving deeper into aldehydes and ketones by focusing on addition reactions of oxygen and nitrogen based nucleophiles. We’ll cover hydrates, acetals and hemiacetals, imines and enamines, and more!
Organic chemistry is a great workout for your brain, and to keep …
Organic chemistry is a great workout for your brain, and to keep its energy up, your brain needs glucose. To maintain blood glucose levels, our bodies go through a process called gluconeogenesis, which involves the important type of organic reaction we’re getting into today: aldol reactions! In this episode of Crash Course Organic Chemistry, we’ll learn what an aldol is, as well as how aldol reactions work and what they do. Plus we’ll learn about a similar reaction, Claisen condensation.
Aldosterone is a steroid hormone which is secreted from the zona glomerulosa …
Aldosterone is a steroid hormone which is secreted from the zona glomerulosa of the adrenal gland. It has a mineralocorticoid activity and is the most important regulator of plasma potassium. When plasma potassium increases, increased stimulation of aldosterone occurs directly and also as a result of the Renin-Angiotensin-Aldosterone System (RAAS). Aldosterone is also the most important regulator of sodium excretion.
In this Interactive Lecture Demonstration, students will predict the main issues that …
In this Interactive Lecture Demonstration, students will predict the main issues that might be included in short French language videos treating topics such as endangered species, organic farming, the effect of aerosols on the environment, pollution and sustainable development. They will then view short videos on the topics and reflect on how their prior assumptions meshed with reality.
Students are introduced to biofuels, biological engineers, algae and how they grow …
Students are introduced to biofuels, biological engineers, algae and how they grow (photosynthesis), and what parts of algae can be used for biofuel (biomass from oils, starches, cell wall sugars). Through this lesson, plants—and specifically algae—are presented as an energy solution. Students learn that breaking apart algal cell walls enables access to oil, starch, and cell wall sugars for biofuel production. Students compare/contrast biofuels and fossil fuels. They learn about the field of biological engineering, including what biological engineers do. A 20-slide PowerPoint® presentation is provided that supports students taking notes in the Cornell format. Short pre- and post-quizzes are provided. This lesson prepares students to conduct the associated activity in which they make and then eat edible algal cell models.
The Algae-in-a-Bottle Experiment provides an engaging and flexible high-impact teaching tool for …
The Algae-in-a-Bottle Experiment provides an engaging and flexible high-impact teaching tool for helping students to know, understand, and apply a number of concepts related to the biology and ecology of aquatic plants and their environments.
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This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"A new algorithm has successfully mapped part of the brain’s circuitry during shock therapy. For those suffering from severe depression, the approach could make for safer and more effective treatment. For brain research at large, it could lead to better ways of untangling noisy neural data to reveal real connections between different focal regions of the brain. Despite the gruesome picture painted by pop culture, modern shock therapy is a mild treatment option. In fact, over 2 million treatments are administered worldwide every year. Under general anesthesia, patients receive a small amount of current to the brain, triggering a brief seizure. The resulting changes in brain chemistry have been shown to reverse symptoms of mental health conditions like severe depression or bipolar disorder. But the procedure isn’t perfect. One of the most troubling side effects is memory loss, a result of poor targeting. To be effective and safe, induced seizures should be restricted to the pre-frontal cortex..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This course is offered to undergraduates and addresses several algorithmic challenges in …
This course is offered to undergraduates and addresses several algorithmic challenges in computational biology. The principles of algorithmic design for biological datasets are studied and existing algorithms analyzed for application to real datasets. Topics covered include: biological sequence analysis, gene identification, regulatory motif discovery, genome assembly, genome duplication and rearrangements, evolutionary theory, clustering algorithms, and scale-free networks.
The horse is a monogastric hindgut fermenter. The horse evolved for grazing …
The horse is a monogastric hindgut fermenter. The horse evolved for grazing and it does so for up to 17 hours a day. A high proportion of the horse's dietary carbohydrate is in the form of starch. A mature horse eats 2-2.5% of it's body weight in dry matter every day, 1.5-1.75% of this should be fibre (hay/haylage). This is to prevent a rapid drop in pH in the large intestine and also to stimulate peristalsis in the gut and prevent build up of gas.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Individuals with metabolic syndrome have a 2-fold increased risk of cardiovascular disease, but few strategies provide adequate cardiovascular risk reduction for this group. One option to lower this risk is to reduce atherogenic lipids, particularly low-density lipoprotein cholesterol. Statins are a recommended first-line therapy for this purpose, but this approach doesn’t always provide sufficient LDL-C lowering to optimally reduce cardiovascular risk. Now, researchers have shown that alirocumab, a proprotein converstase subtilisin/kexin type 9 inhibitor, or PCSK9 inhibitor, approved for LDL-C reduction, may address this need. Pooled clinical trial data from ten phase 3 clinical trials from the ODYSSEY clinical development program showed alirocumab significantly lowered LDL-C in individuals both with and without metabolic syndrome..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Alirocumab, a drug that inhibits PCSK9 and helps clear the blood of atherogenic lipids, may be of benefit for individuals with type 2 diabetes who are most at risk of cardiovascular disease. According to the International Diabetes Federation, heart disease is the leading cause of death among people with type 2 diabetes. One factor that might contribute to that grim statistic is the high mixed dyslipidemia prevalence in this population. Mixed dyslipidemia is characterized by elevated triglycerides, and hence high triglyceride-rich lipoprotein, or remnant cholesterol, and high cholesterol levels; and low serum levels of high-density lipoprotein cholesterol, or HDL-C. Despite treatment with statins and other lipid-lowering therapies targeting atherogenic lipoproteins, management of mixed dyslipidemia remains challenging, especially among individuals with diabetes..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
Alkanes are kind of the wallflowers of organic chemistry, but they still …
Alkanes are kind of the wallflowers of organic chemistry, but they still have important functions in the world around us. In this episode of Crash Course Organic Chemistry we’re building our knowledge of organic molecules by learning all about these so called couch potatoes from how they are separated from crude oil to how to use Newman projections to predict torsional strain and steric hinderance. We’ll also learn the names of some common conformers and get an introduction to cycloalkanes.
Like a trendy dance, a fighting combo, or a secret handshake, organic …
Like a trendy dance, a fighting combo, or a secret handshake, organic reactions can be broken down into simpler steps. In this episode of Crash Course Organic Chemistry, we’ll specifically be looking at alkene addition reactions, and with each new reaction ask ourselves three questions to help us puzzle through the mechanism and understand what’s going on.
Oxidation-reduction reactions are going on around us, and inside us, all the …
Oxidation-reduction reactions are going on around us, and inside us, all the time, and we can make redox reactions in organic chemistry easier to understand by tracking carbon-oxygen bonds. In this episode of Crash Course Organic Chemistry, we’ll focus on alkene redox reactions and revisit our 3-part secret handshake to help us better understand patterns and predict the products of these reactions.
Carbon-carbon double bonds are pretty common in nature, but triple bonds between …
Carbon-carbon double bonds are pretty common in nature, but triple bonds between carbons, called alkynes, are not. When alkynes do pop up in nature, it’s usually in a compound that’s toxic to humans, however, we can synthesize alkynes that are life saving medicines and materials. In this episode of Crash Course Organic Chemistry, we’ll learn about alkynes and some of the reactions we can use them in (hint: it’s a lot of the same reactions we used for alkenes!)
"Normally, an animal gets half its DNA from its mother and half …
"Normally, an animal gets half its DNA from its mother and half from its father. But Dolly had three mothers: one mother gave Dolly her DNA; one supplied an egg; and the third, her surrogate mother, gave birth to her. Dolly is an identical twin of the mother who gave her her DNA. But Dolly is six years younger."This kid-friendly Web page helps kids understand how and why Dolly was cloned, and understand the potential benefits of cloning as well as the controversy it raises.
Join Simon, Anita, Emily and the rest of Ms. Patel's class as …
Join Simon, Anita, Emily and the rest of Ms. Patel's class as they gain an understanding of how the Earth works as a system while preparing their end of the school year play.
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