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Pathology Case Study: An 81 year-old woman with complaint of weakness
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(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

An 81 year-old female presented to the emergency department with complaints of blood in her urine and stool for 1 day and new onset of weakness. She has a history of congestive heart failure, type 2 diabetes, and nonalcoholic steatohepatitis. She had a cough one week ago. At presentation she appeared jaundiced. The patient had no recent blood transfusions. Relevant laboratory values (Table 1) and blood bank test results (Table 2) are reported below.

Subject:
Applied Science
Education
Health, Medicine and Nursing
Life Science
Material Type:
Case Study
Diagram/Illustration
Provider:
University of Pittsburgh School of Medicine
Provider Set:
Department of Pathology
Author:
Daniel D. Rhoads
Lirong Qu
Sarah Harm
Date Added:
08/01/2022
Pathology Case Study: An Adolescent Female with Abdominal Fullness and Distension
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(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

Her initial physical exam in the emergency department revealed a distended, non-tender lower abdomen with a large palpable midline mass. The remainder of her physical exam was unremarkable. Initial laboratory workup was unremarkable, including normal levels AFP, hCG, LDH, CEA-125, and estriol. She underwent ultrasound of the abdomen and CT scan of the chest, abdomen, and pelvis (Figure 1). The CT scan revealed a solid, enhancing, 19 x 12 x 10 cm multilobulated mass arising from the left aspect of the uterus. This mass distorted the endometrial cavity and exerted significant mass effect on the iliac veins, iliac arteries, and distal ureters. The remainder of the abdominal and thoracic CT was unremarkable. The initial interpretation was worrisome for uterine malignancy, such as leiomyosarcoma or other uterine sarcomas. There was also some concern, based on the combined interpretation of the CT and ultrasound, that the mass could be arising from one or both ovaries. After discussion with the patient and her family of the above findings, and because the patient was clinically stable, she was discharged to home with short interval follow-up. A subsequent MRI of the abdomen and pelvis two days later as an outpatient showed normal appearing ovaries and re-demonstrated the large uterine mass (Figure 2).

Subject:
Applied Science
Education
Health, Medicine and Nursing
Life Science
Material Type:
Case Study
Diagram/Illustration
Provider:
University of Pittsburgh School of Medicine
Provider Set:
Department of Pathology
Author:
Daniel Marker
Jennifer Picarsic
Date Added:
08/01/2022
Pathology Case Study: A woman in her 20s with bifrontal headaches
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(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

A woman in her 20s presented with a one-year history of bifrontal headaches that had recently worsened. After admission to the hospital, the patient displayed no other symptoms and no acute worsening of the headaches.

Subject:
Applied Science
Education
Health, Medicine and Nursing
Life Science
Material Type:
Case Study
Diagram/Illustration
Provider:
University of Pittsburgh School of Medicine
Provider Set:
Department of Pathology
Author:
Chris Englund
Daniel Silbergeld
Ellsworth C. Alvord
Jr.
Randy Small
Robert F. Hevner
Date Added:
08/01/2022
Pathology Case Study: A woman in her 50s with acute loss of strength in her right upper extremity and slurred speech
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(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

Physical examination showed normal vital signs. There was no difficulty breathing, chest pain, or headache. Neurologic evaluation demonstrated an awake and alert, right-handed female oriented to person, place, and time. She was noted to have persistent word finding difficulty and was unable to name a pen and a watch. At the time of neurological testing, the patient's motor and sensory function had essentially returned to normal. Cranial nerves were intact bilaterally and deep tendon reflexes were symmetric and slightly reduced. Her gait was unremarkable and Romberg testing was negative.

Subject:
Applied Science
Education
Health, Medicine and Nursing
Life Science
Material Type:
Case Study
Diagram/Illustration
Provider:
University of Pittsburgh School of Medicine
Provider Set:
Department of Pathology
Author:
Amilcar A Castellano-Sanchez
Daniel J Brat
Date Added:
08/01/2022
Pathology Case Study: Male Toddler with  Developmental Delays and Behavioral Issues
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(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

The patient started early intervention shortly after the onset of symptoms, but therapies were limited due to his oppositional behaviors. After evaluation by a developmental pediatrician, he did not meet diagnostic criteria for autism spectrum disorder. The physical exam was unremarkable, an audiology test was normal, and a brain MRI showed no evidence of focal parenchymal abnormality. Given the patient's medical history, global developmental delays, behavioral issues, as well as a family history of a maternal uncle with brain malformation and similar behavioral issues further genetic testing was undertaken. SNP micro-array analysis was negative for copy number alterations. FMR1 gene mutation analysis by PCR for Fragile X Mental Retardation is shown in Figure 1.

Subject:
Applied Science
Education
Health, Medicine and Nursing
Life Science
Material Type:
Case Study
Diagram/Illustration
Provider:
University of Pittsburgh School of Medicine
Provider Set:
Department of Pathology
Author:
Daniel Geisler
Tim D. Oury
Date Added:
08/01/2022
Pedro Albizu Campos Digital Resource Collection
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CC BY-NC-ND
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The Pedro Albizu Campos Digital Resource Collection contains digitized images of all of the archival documents of Pedro Albizu Campos maintained by Harvard University Archives (HUA). The collection focuses on 1912-1923 (the date of Albizu’s official Harvard Law School degree conferral). The digital images are of every single document of Pedro Albizu Campos from the University of Vermont, Harvard College, and Harvard Law School. It includes newspaper clippings in Albizu’s alum file and Laura Meneses del Carpio, wife of Albizu, maintained by Radcliffe College. The collection includes Spanish translations of most digital images and English text for most handwritten letters and notes.

Subject:
History
History, Law, Politics
Material Type:
Primary Source
Author:
Dr. Daniel Ibarrondo Cruz
Date Added:
08/15/2023
Plotting and Programming in Python
Unrestricted Use
CC BY
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This lesson is part of Software Carpentry workshops and teach an introduction to plotting and programming using python. This lesson is an introduction to programming in Python for people with little or no previous programming experience. It uses plotting as its motivating example, and is designed to be used in both Data Carpentry and Software Carpentry workshops. This lesson references JupyterLab, but can be taught using a regular Python interpreter as well. Please note that this lesson uses Python 3 rather than Python 2.

Subject:
Applied Science
Computer Science
Information Science
Mathematics
Measurement and Data
Material Type:
Module
Provider:
The Carpentries
Author:
Adam Steer
Allen Lee
Andreas Hilboll
Ashley Champagne
Benjamin
Benjamin Roberts
CanWood
Carlos Henrique Brandt
Carlos M Ortiz Marrero
Cephalopd
Cian Wilson
Dan Mønster
Daniel W Kerchner
Daria Orlowska
Dave Lampert
David Matten
Erin Alison Becker
Florian Goth
Francisco J. Martínez
Greg Wilson
Jacob Deppen
Jarno Rantaharju
Jeremy Zucker
Jonah Duckles
Kees den Heijer
Keith Gilbertson
Kyle E Niemeyer
Lex Nederbragt
Logan Cox
Louis Vernon
Lucy Dorothy Whalley
Madeleine Bonsma-Fisher
Mark Phillips
Mark Slater
Maxim Belkin
Michael Beyeler
Mike Henry
Narayanan Raghupathy
Nigel Bosch
Olav Vahtras
Pablo Hernandez-Cerdan
Paul Anzel
Phil Tooley
Raniere Silva
Robert Woodward
Ryan Avery
Ryan Gregory James
SBolo
Sarah M Brown
Shyam Dwaraknath
Sourav Singh
Steven Koenig
Stéphane Guillou
Taylor Smith
Thor Wikfeldt
Timothy Warren
Tyler Martin
Vasu Venkateshwaran
Vikas Pejaver
ian
mzc9
Date Added:
08/07/2020
Poetry Unit
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CC BY-NC-SA
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This resource provides lecture notes and writing assignments for the study of poetry. While specific poems are presented here, these notes and assignments can be adapted and applied to practically any thematic group of poems.  The unit contains several modules. The first posits the work of African American poet Langston Hughes as poems that establish a legacy of oratorical poems addressing social issues faced not only by African Americans, but by any and all Americans, especially the historically disenfranchised.  The unit explores poems in Hughes' legacy, focusing on three poems by African American poets Maya Angelou, Elizabeth Alexander, and Amanda Gorman, who composed U.S. presidential inaugural poems. The second module explores nature poetry. Students read and analyze poems that explore, ponder and sometimes celebrate the relationship between human beings and nature. Ultimately, students compose poetry explication essays. The third module explores the book-length prose poem "I Remember" (Joe Brainard), teaching students to locate and make use of peer-reviewed articles.  Additionally, students write their own "I Remember" poems. Included are introductory lecture, discussion , short writing, explication , and several other assignments. Unless otherwise noted, the materials in this unit are licensed under CC BY-NC-SA.

Subject:
Arts and Humanities
Composition and Rhetoric
English Language Arts
Literature
Reading Literature
Material Type:
Activity/Lab
Homework/Assignment
Lesson
Module
Unit of Study
Author:
Nina Adel
Judith Westley
Daniel Kelley
Graham Harkness
Date Added:
07/22/2021
Practical Programming in C
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CC BY-NC-SA
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This course provides a thorough introduction to the C programming language, the workhorse of the UNIX operating system and lingua franca of embedded processors and micro-controllers. The first two weeks will cover basic syntax and grammar, and expose students to practical programming techniques. The remaining lectures will focus on more advanced concepts, such as dynamic memory allocation, concurrency and synchronization, UNIX signals and process control, library development and usage. Daily programming assignments and weekly laboratory exercises are required. Knowledge of C is highly marketable for summer internships, UROPs, and full-time positions in software and embedded systems development.

Subject:
Applied Science
Computer Science
Engineering
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Chikkerur, Sharat
Weller, Daniel
Date Added:
01/01/2010
Pragmatics in Linguistic Theory
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CC BY-NC-SA
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The course introduces formal theories of context-dependency, presupposition, implicature, context-change, focus and topic. Special emphasis is on the division of labor between semantics and pragmatics. It also covers applications to the analysis of quantification, definiteness, presupposition projection, conditionals and modality, anaphora, questions and answers.

Subject:
Arts and Humanities
Linguistics
Social Science
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Fox, Daniel
Menéndez-Benito, Paula
Date Added:
09/01/2006
Pre-analysis Plans: A Stocktaking
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The evidence-based community has championed the public registration of pre-analysis plans (PAPs) as a solution to the problem of research credibility, but without any evidence that PAPs actually bolster the credibility of research. We analyze a representative sample of 195 pre-analysis plans (PAPs) from the American Economic Association (AEA) and Evidence in Governance and Politics (EGAP) registration platforms to assess whether PAPs are sufficiently clear, precise and comprehensive to be able to achieve their objectives of preventing “fishing” and reducing the scope for post-hoc adjustment of research hypotheses. We also analyze a subset of 93 PAPs from projects that have resulted in publicly available papers to ascertain how faithfully they adhere to their pre-registered specifications and hypotheses. We find significant variation in the extent to which PAPs are accomplishing the goals they were designed to achieve

Subject:
Economics
Social Science
Material Type:
Reading
Author:
Daniel Posner
George Ofosu
Date Added:
08/07/2020
Preparing Your Students for the Future: Undergraduate Research Experiences with RapidCycling Brassic
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CC BY-NC-SA
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This article with practical instructions about using Fast Plants in undergraduate research experiences was published as an addendum to a workshop given at the 2017 ABLE Conference in Madison, WI. Contains ideas for helping students at high school and undergraduate levels to conduct independent research. Published in Tested Studies for Laboratory Teaching Proceedings of the Association for Biology Laboratory Education Volume 39, Article 11, 2018

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Author:
Daniel W. Lauffer
Hedi Baxter Lauffer
Jackson Hetue
Date Added:
05/25/2023
Principios Básicos de Bioquímica para Agroecología
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CC BY-NC-SA
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El libro "Principios Básicos de Bioquímica para Agroecología" es una obra que busca proporcionar a los estudiantes de esta disciplina una base sólida en los fundamentos de la bioquímica, escrita por un equipo de docentes investigadores, se presenta como un recurso didáctico para aquellos estudiantes que buscan comprender la relación entre la química, la bioquímica y la agricultura, iniciando con la definición conceptual de bioquímica. A medida que avanza el texto, se profundiza en los conceptos de estructuras de la célula vegetal, sus características y funciones, así como también se describen las proteínas, lípidos, carbohidratos y ácidos nucleicos. Además, aborda temas importantes para la agroecología, como la fotosíntesis y la función de los nutrientes en las plantas. El enfoque en estos temas permite a los estudiantes de agroecología entender cómo los principios de la bioquímica son relevantes para el estudio de la agricultura y la producción de alimentos. Así también incluye una variedad de recursos de apoyo para el aprendizaje, como cuadros, tablas, diagramas y ejemplos. Estos recursos ayudan a los estudiantes a visualizar y comprender los conceptos difíciles de la bioquímica, y a aplicarlos a situaciones del mundo real. Una de las características más destacadas de este documento es su lenguaje accesible y fácil de entender. Los autores han evitado el uso excesivo de terminología técnica y han explicado los conceptos de manera clara y concisa. Esto hace que sea adecuado para estudiantes de diversos niveles y antecedentes académicos. En conclusión, es material bibliográfico valioso y esencial para cualquier estudiante que desee comprender los principios básicos de la bioquímica y su aplicación en el campo de la agroecología. Con una escritura clara, recursos de apoyo útiles y un enfoque en temas relevantes para la agricultura, representa una excelente herramienta para el aprendizaje y la comprensión de la bioquímica y su relación con la producción de alimentos.

Subject:
Agriculture
Career and Technical Education
Material Type:
Textbook
Provider:
Editorial Grupo AEA
Author:
Luis Daniel Hidalgo-Hugo
María de Lourdes Correa-Salgado
Robinson Jasmany Herrera-Feijoo
Date Added:
06/29/2023
Principles of Political Economy
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CC BY-NC-SA
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The PDF file available here is ideal for creating a print version of the textbook. This textbook offers a pluralistic approach to microeconomic theory, macroeconomic theory, and international economic theory. It adopts a critical approach to neoclassical economics and incorporates heterodox alternatives to mainstream economics throughout the book.

Subject:
Economics
Social Science
Material Type:
Textbook
Author:
Daniel E. Saros
Date Added:
06/12/2019
Probability and Statistics in Engineering
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CC BY-NC-SA
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This class covers quantitative analysis of uncertainty and risk for engineering applications. Fundamentals of probability, random processes, statistics, and decision analysis are covered, along with random variables and vectors, uncertainty propagation, conditional distributions, and second-moment analysis. System reliability is introduced. Other topics covered include Bayesian analysis and risk-based decision, estimation of distribution parameters, hypothesis testing, simple and multiple linear regressions, and Poisson and Markov processes. There is an emphasis placed on real-world applications to engineering problems.

Subject:
Applied Science
Engineering
Mathematics
Material Type:
Full Course
Provider Set:
MIT OpenCourseWare
Author:
Veneziano, Daniele
Date Added:
02/01/2005
Project Organization and Management for Genomics
Unrestricted Use
CC BY
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Data Carpentry Genomics workshop lesson to learn how to structure your metadata, organize and document your genomics data and bioinformatics workflow, and access data on the NCBI sequence read archive (SRA) database. Good data organization is the foundation of any research project. It not only sets you up well for an analysis, but it also makes it easier to come back to the project later and share with collaborators, including your most important collaborator - future you. Organizing a project that includes sequencing involves many components. There’s the experimental setup and conditions metadata, measurements of experimental parameters, sequencing preparation and sample information, the sequences themselves and the files and workflow of any bioinformatics analysis. So much of the information of a sequencing project is digital, and we need to keep track of our digital records in the same way we have a lab notebook and sample freezer. In this lesson, we’ll go through the project organization and documentation that will make an efficient bioinformatics workflow possible. Not only will this make you a more effective bioinformatics researcher, it also prepares your data and project for publication, as grant agencies and publishers increasingly require this information. In this lesson, we’ll be using data from a study of experimental evolution using E. coli. More information about this dataset is available here. In this study there are several types of files: Spreadsheet data from the experiment that tracks the strains and their phenotype over time Spreadsheet data with information on the samples that were sequenced - the names of the samples, how they were prepared and the sequencing conditions The sequence data Throughout the analysis, we’ll also generate files from the steps in the bioinformatics pipeline and documentation on the tools and parameters that we used. In this lesson you will learn: How to structure your metadata, tabular data and information about the experiment. The metadata is the information about the experiment and the samples you’re sequencing. How to prepare for, understand, organize and store the sequencing data that comes back from the sequencing center How to access and download publicly available data that may need to be used in your bioinformatics analysis The concepts of organizing the files and documenting the workflow of your bioinformatics analysis

Subject:
Business and Communication
Genetics
Life Science
Management
Material Type:
Module
Provider:
The Carpentries
Author:
Amanda Charbonneau
Bérénice Batut
Daniel O. S. Ouso
Deborah Paul
Erin Alison Becker
François Michonneau
Jason Williams
Juan A. Ugalde
Kevin Weitemier
Laura Williams
Paula Andrea Martinez
Peter R. Hoyt
Rayna Michelle Harris
Taylor Reiter
Toby Hodges
Tracy Teal
Date Added:
08/07/2020
Psychcinct Unit 1: INTRODUCTION TO PSYCHOLOGY part 1 of 3
Unrestricted Use
CC BY
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Intern Prescot Nelson at Succinct Psychology (Psychcinct), under the guidance of professor Daniel Reynolds, created the entire course series for the Psych2e Openstax textbook. We are allowing everyone to share and embed this resource.

Subject:
Psychology
Social Science
Material Type:
Full Course
Lecture
Lesson
Module
Unit of Study
Author:
Daniel Reynolds
Prescot Nelson
Date Added:
05/01/2021
Pushing It Off a Cliff
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Educational Use
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This lesson focuses on the conservation of energy solely between gravitational potential energy and kinetic energy, moving students into the Research and Revise step. Students start out with a virtual laboratory, and then move into the notes and working of problems as a group. A few questions are given as homework. A dry lab focuses on the kinetic and potential energies found on a roller coaster concludes the lesson in the Test Your Mettle phase of the Legacy Cycle.

Subject:
Applied Science
Engineering
Physical Science
Physics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Joel Daniel
Date Added:
09/18/2014
Quantifying the Energy Associated with Everyday Things and Events
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CC BY-NC-SA
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The topic of this video is energy in general, and specifically the ways we can quantify it. In order to make the concepts accessible to a broad audience, this video focuses on everyday things and events. How is it that energy plays a part in a child riding a scooter? How is the energy we consume in playing related to the energy on the food we eat? This video poses these questions to the class and challenges them to put a list of five such items into an ordering from most energy to least.

Subject:
Physical Science
Physics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Daniel D. Frey
Date Added:
09/09/2015