Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

This series of instructional videos was created by Camosun College for a Canadian edition of the OpenStax "Concepts of Biology" open textbook as part of the BC Open Textbook Project. The lectures are taught by Charles Molnar, a Biology instructor at Camosun College. The videos are accompanied by transcripts.

As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

The goal of these lessons, packaged under the title “A Day in the Life of a Protein,” is to select an example that is not only real world, but also is connected to many of the topics taught in the course. The specific protein used here is Hemoglobin A, looking at the mutation leading to sickle cell anemia. Other proteins could be substituted into this model as needed.

In this visualization adapted from the University of Massachusetts Medical School, discover the role that dengue viral proteins play in a human cell as the virus prepares to replicate.

The module named 'Diet for Healthy Living' consists some important dimensions of diet for healthy living, which include nutrion, nutrients, food group and balanced diet.  This module contains videos, activities, questions, material and resources.At the end of the lesson, there is a link of google form to assess yourself. It also include an extended learning section where learners can go through for further information.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Malignant gliomas are the most common and the deadliest type of tumor affecting the central nervous system. Even after surgery, chemotherapy, and radiotherapy, gliomas can still have a poor prognosis. But growing evidence is pointing to one promising target for fighting glioma. Exosomes are tiny sacs of cellular matter implicated in numerous cell processes. including signaling and communication and glioma progression. miRNAs are among the most important glioma-related payloads shuttled between cells by exosomes. In addition to increasing the risk of developing glioma. miRNAs can confer chemotherapy drug resistance from one cell to another or they can even help inhibit glioma tumor growth. Researchers are discovering that exosomal proteins may play similar roles. Understanding how exosomes operate and how they might be manipulated. could help researchers and clinicians deliver more powerful anti-cancer therapies to patients with glioma..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

This work consists of original content and adapted OpenStax content. Each image is attributed with the source page in the figure description, in accordance to each respective license. OpenStax content has been remixed into the “Theory and Background” and “Relations to Health Sciences” sections of this work. OpenStax remixing consists of rearrangement, minor instructional design augmentations, and minor phrasing edits. All other sections within this work are originally created content.

Student teams learn about engineering design of green fluorescent proteins (GFPs) and their use in medical research, including stem cell research. They simulate the use of GFPs by adding fluorescent dye to water and letting a flower or plant to transport the dye throughout its structure. Students apply their knowledge of GFPs to engineering applications in the medical, environmental and space exploration fields. Due to the fluorescing nature of the dye, plant life of any color, light or dark, can be used unlike dyes that can only be seen in visible light.

Help Me Understand Genetics presents basic information about genetics in clear language and provides links to online resources.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"High-temperature frying might produce delicious food... But it also carries certain health risks One lesser-known risk is difficulty breathing New research published in the journal Indoor Air shows that high-temperature frying can generate harmful emissions Exposure to frying fumes can irritate the airways and lead to respiratory symptoms Researchers showed that the fumes produced from heating protein-rich foods to temperatures over 250°C (482°F) carry toxic compounds such as isocyanic acid These compounds are produced from the nitrogen found in amino acids Exposure to isocyanic acid can damage proteins found in the airways, potentially causing respiratory symptoms The good news is that the toxic constituents in frying fumes vary depending on cooking style, cooking temperature, and whether the food being cooked is protein-rich Protein-rich foods cooked at or below 200°C (390°F) generate very little of these toxic gases....."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Residing in the stomachs of over half the human population, the bacterium Helicobacter pylori, also known as H pylori, has become a major cause of digestive complications, ranging from peptic ulcers to stomach cancer. But despite this link, scientists still aren’t sure how these disorders arise after infection. Now, researchers have homed in on a single protein produced by H pylori that seems to rev up the immune system, causing a state of inflammation that may pave the way for cancer growth or other types of gut breakdown. The protein, HP1454, is naturally released from H pylori -- both actively by living cells and passively as cells die. The scientists found that when special immune cells known as T cells encounter this secreted HP1454, they kick into action, mounting an inflammatory response. This relationship was particularly strong in people with stomach cancer..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Students conduct their own research to discover and understand the methods designed by engineers and used by scientists to analyze or validate the molecular structure of DNA, proteins and enzymes, as well as basic information about gel electrophoresis and DNA identification. In this computer-based activity, students investigate particular molecular imaging technologies, such as x-ray, atomic force microscopy, transmission electron microscopy, and create short PowerPoint presentations that address key points. The presentations include their own explanations of the difference between molecular imaging and gel electrophoresis.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.012 focuses on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.
Acknowledgments
The study materials, problem sets, and quiz materials used during Fall 2004 for 7.012 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course #7.012. Since the following works have evolved over a period of many years, no single source can be attributed.

Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

The MIT Biology Department core Introductory Biology courses, 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. The focus of 7.013 is on genomic approaches to human biology, including neuroscience, development, immunology, tissue repair and stem cells, tissue engineering, and infectious and inherited diseases, including cancer.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. 7.013 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution.
Biological function at the molecular level is particularly emphasized in all courses and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.014 focuses on the application of these fundamental principles, toward an understanding of microorganisms as geochemical agents responsible for the evolution and renewal of the biosphere and of their role in human health and disease.
Acknowledgements
The study materials, problem sets, and quiz materials used during Spring 2005 for 7.014 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course 7.014. Since the following works have evolved over a period of many years, no single source can be attributed.