The focus of this presentation is to expand the students’ knowledge about the Human Gut Microbiome. The gut is - similar to the skin - exposed externally and is therefore a non-sterile environment.
In this presentation, we will tell you about dermal gel fillers and infections related to these. Dermal gel fillers have become increasingly popular during the past 15-20 years, because they can restore some of the youthful appearance in an ageing face. The fillers differ in longevity and composition, some contain micro particles and others do not.
The aim of this presentation is to expand the students’ knowledge about treatment of chronic infections in relation to orthopedic surgery. In the field of orthopedic surgery, several chronic infections exist and sometimes they combine.
In this presentation, we will discuss how to treat chronic infections. In continuation of this, we will discuss some of the issues that one might consider when treating biofilm-associated infections.
Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.
By the end of this section, you will be able to:Identify bacterial diseases that caused historically important plagues and epidemicsDescribe the link between biofilms and foodborne diseasesExplain how overuse of antibiotic may be creating “super bugs”Explain the importance of MRSA with respect to the problems of antibiotic resistance
By the end of this section, you will be able to:Describe the evolutionary history of prokaryotesDiscuss the distinguishing features of extremophilesExplain why it is difficult to culture prokaryotes
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Adherent-invasive E. coli, or AIEC, are bacteria that are abnormally abundant in the gut of individuals with Crohn’s disease, a chronic inflammatory disease that affects the lining of the gastrointestinal tract. To determine whether targeting AIEC could help relieve symptoms of Crohn’s disease, researchers recently explored the possibility of simply making these bacteria less sticky. The team applied a compound known as TAK-018 to gut samples gathered from patients. TAK-018 binds to the bacterial adhesin FimH, blocking bacteria clinging and interaction with cells along the intestinal wall. Tests revealed that TAK-018 not only prevented AIEC bacteria from adhering to intestinal tissue but also reduced inflammation, helping preserve the integrity of this important barrier. While more work is needed to understand how TAK-018 operates in the body, the drug is known to be safe and well-tolerated in patients and is currently undergoing phase II testing for the treatment of Crohn’s disease..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Biofilms are the slimy cities some microbes form when they invade a surface. Conventional cleaning products are generally good at breaking up biofilms. But they tend to be harsh on the environment. And while natural products are a good alternative, it takes multiple enzymes to break up the strong polymers that make bacteria stick. But researchers are confident that a natural solution does exist. One team searched the forest floor in the Netherlands for microbes that might produce an all-in-one biofilm-busting enzyme. To coax those microbes out, they enriched forest litter with an especially tough biopolymer produced by forest bacteria: Acidobacteria. Microbes that could thrive in that environment likely produced enzymes strong enough to degrade the biopolymer blend. Analyses indicated the predominance of four bacterial phyla. More importantly, they revealed the main type of enzyme these bacteria secreted: glycoside hydrolases..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"The first human spaceflight to Mars is expected to take place sometime within the next decade, and its success will be highly dependent on the health of its crew. The human microbiome, or the community of microorganisms inhabiting the body, has critical effects on human health, but how the journey to another planet will affect it has yet to be determined. During a space mission, the crew will experience microgravity, increased cosmic radiation, isolation, food limitations, and other stressors. While data from simulations and the International Space Station suggest that the human microbiome may be resilient to these conditions, frequent monitoring during the spaceflight will still be necessary to safeguard crew health. Microbiome perturbations will need to be actively prevented, and the establishment of a computer-based warning system will allow microbe-related disease to be quickly detected..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Gas biofilters can help remove harmful volatile organic compounds (VOCs) from the air through the action of microorganisms immobilized on the filler surface. However, unchecked growth of these microbes can clog the filters, reducing filtration performance. Quorum quenching (QQ) is known to impair bacterial biofilm formation by disrupting bacterial communication, but it’s unclear whether it can prevent microbial clogging of gas biofilters. To find out, researchers recently operated gas biofilters with and without the QQ bacterium Rhodococcus sp. BH4 in parallel. Both the normal biofilter and the QQ biofilter removed aromatic compounds from the air, but the QQBF accumulated less biomass and functioned more stably. The bacteria in the QQBF made lower amounts of extracellular polymeric substances (EPSs) thus producing a less-adhesive biofilm that degraded more easily . The QQ biofilter also had lower abundance of quorum-sensing bacteria and quorum-sensing genes. Although the mechanism of Rhodococcus sp..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Plastics have countless uses. However, the mismanagement of plastic waste has resulted in widespread ocean pollution, which could persist in the marine environment for hundreds of years. But growing research suggests that certain microorganisms could be harnessed to break down this waste. The key is verifying whether plastic-degrading microorganisms actually occur in the biofilms that colonize the surfaces of plastic particles, or the “plastisphere", and understanding their temporal characteristics. Recently, researchers found a high diversity of microbes that varied in their community composition over time when cultured on different types of polyethylene terephthalate (PET) plastic. They also found evidence of PET degradation by these microorganisms based on a combined proteogenomic and metabolomic approach, which confirmed that two newly identified isolates from these communities are able to degrade PET using different pathways, one of which may be novel..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Fixing carbon through biological methanation is a promising technology for generating renewable energy. It remains unclear, however, how microbial species interact to generate biogas. To find out, researchers explored the community dynamics of microbes found in biofilms from four biogas reactors. Metagenomics revealed 59 species of microbes with five accounting for more than 70% of total abundance in the four reactors under investigation. Experiments showed that Firmicutes spp. GSMM966 and GSMM974 and Limnochordia sp. GSMM975 played a central role in biofilm formation. And metabolic reconstruction indicated complex metabolisms for the two dominant species M. wolfeii GSMM957 and Limnochordia sp. GSMM975. Simulations of the core biofilm community showed that these same species exhibit the highest increases in growth rate with increasing uptake. And cross-feeding interactions, not easily measured in vivo, were visualized..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"The rumen is the largest compartment of the ruminant forestomach and houses a complex microbiome. That microbiome greatly influences gut energy harvesting capacity. Improving our understanding of the mechanisms that influence energy harvesting capacity could be used to optimize ruminant feed efficiency and management. Thus, researchers recently examined temporal ecological interactions at the plant-biofilm interface by incubating fresh perennial ryegrass in cattle rumens and analyzing the bacterial diversity and gene expression at several time points. Network analysis identified two sub-microbiomes. They represented the primary (<4h) and secondary (>4h) colonization phases. Several of the most transcriptionally active microbial families didn't interact with either sub-microbiome, which suggests non-cooperative behavior. Conversely, the putative keystone families of each sub-microbiome had low transcriptional activity..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.