This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Nutrient-poor diets can increase the risk of neurodegenerative diseases such as Alzheimer’s, and diets poor in fiber are widespread, especially in industrialized nations. However, whether fiber deficiency—which alters the gut microbiota—impairs cognition through the gut–brain axis remains unclear. To find out, researchers recently analyzed mice fed a fiber-deficient diet for 15 weeks. Compared to normal mice, the fiber-deficient mice exhibited cognitive impairment and were unable to complete typical activities like nest organization. In addition, the synapses in the brain area regulating cognitive function were damaged, and neuroinflammation occurred. Immune cells called microglia (indicated by Iba1) engulfed synapses (indicated by PSD-95) in the fiber-deficient mice. Furthermore, the fiber-deficient mice exhibited gut microbiota disruption that was associated with, and possibly responsible for, the cognitive deficits..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The composition of the gut microbiome is affected by diet as well as obesity, which can itself be diet-related, but the comparative influences of these factors are unclear. To explore the complex interactions among diet, obesity, and gut microbes, researchers examined female monkeys fed either a Western or Mediterranean diet. Metagenomic sequencing of fecal samples revealed that diet was the main contributor to gut bacterial diversity. Compared with the Western diet group, the Mediterranean diet group had greater overall diversity and different abundance of 54 bacterial species. Within each diet group, leaner and heavier monkeys also had subtly different microbiomes. Interestingly, the Western diet-fed group had more Prevotella copri and had high-P. copri and low-P. copri subgroups. High-P. copri monkeys had lower diversity than low-P. copri monkeys and different proportions of some microbes. Untargeted metabolomics of urine and plasma also suggested that the high-P..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Thisslide will help students understand the difference between an immunogen and an antigen. Students can understand how a hapten which is non immunogenic can be converted to an immunogen by linking it to a carrier molecule.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"This is germ cell-expressed protein (GCE). Across the scientific literature, GCE is treated as equivalent to Methoprene tolerant protein (MET) as both are hormone receptors that prevent the premature development of the common fruit fly. But a new study indicates that subtle structural differences between GCE and MET contribute to functional distinctions that should make each protein a unique object of research. These differences lie along the long C-terminal fragments of the proteins, dubbed GCEC and METC. Structural characterization experiments suggest that GCEC is a long, asymmetrical, and coil-like intrinsically disordered protein. Compared with METC, GCEC is less compact, contains more molecular recognition elements, and is more susceptible to folding. That, according to NMR data, enables GCEC to interact with the nuclear receptor FTZ-F1. which can force GCEC to adopt a more fixed structure and different function than METC..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Small extracellular vesicles (sEVs) mediate intercellular communication by carrying RNA, proteins, and lipids between cells. These cargo molecules mirror the physiological state of their donor cells, but they are selectively loaded into sEVs. sEVs can cross the blood-brain barrier, and their contents may be influenced by neurological disorders, making them potential biomarkers. Identifying cell-specific signatures could be an important first step in the biomarker discovery process. Recently researchers examined sEVs isolated from cultures of primary mouse cortical neurons and astrocytes. They identified distinct total RNA and miRNA profiles between the two cell types. While astrocytes had a greater number of detected miRNAs than neurons, neurons expressed more sEV-associated miRNAs than astrocytes. They also identified short miRNA sequence motifs that were differentially loaded to or excluded from sEVs..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Differentiating open access and open educational resource can be a challenge in some contexts. Excellent resources such as "How Open Is It?: A Guide for Evaluating the Openness of Journals" (CC BY) https://sparcopen.org/our-work/howopenisit created by SPARC, PLOS, and OASPA greatly aid us in understanding the relative openness of journals. However, visual resources to conceptually differentiate open educational resources (OER) from resources disseminated using an open access approach do not currently exist. Until now.

This one page introductory guide differentiates OER and OA materials on the basis of purpose (teaching vs. research), method of access (analog and digital), and in terms of the relative freedoms offered by different levels of Creative Commons licenses, the most common open license. Many other open licenses, including open software licenses also exist.

As taught Semesters 1 and 2, 2011

This learning object describes As taught Semesters 1 and 2, 2011

The learning object distinguishes between some examples of different types of cells on the basis of their microscopic appearance. The learning object is used as part of the level 1 Biological Sciences module delivered by the School of Nursing, Midwifery and Physiotherapy.

Dr Andy Meal, Lecturer in Biological Sciences, School of Nursing, Midwifery and Physiotherapy

As taught Semesters 1 and 2, 2011

This learning object which is used as part of the level 1 Biological Sciences module delivered by the School of Nursing, Midwifery and Physiotherapy relates the microscopic appearance and structure of epithelia to their function.

Andy Meal, Lecturer in Biological Sciences, School of Nursing, Midwifery and Physiotherapy

Gases or liquids can be unevenly distributed between two areas. If one area has a higher concentration than the other then the differance between these two areas is termed the concentration gradient. The equality is then corrected by the movement of the molecules down this so called gradient from the region of high concentration to that of low. This process is passive as the molecules do not have to be forced to do this and it is reffered to as diffusion.

Poster showing horse-drawn ploughing, soldiers on the battlefield, and men in line to purchase Liberty bonds. Copyright H.F. Rawll, 303 Hudson Street, N.Y. City. No. 3608N4

This lesson looks at the structures and functions of the digestive system with illustrated diagrams and assessment.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"It might not be your first choice for a meal, but many mammals appear to find earth an appetizing addition to their diet Known as geophagy, scientists still aren’t sure what causes the surprisingly common urge to eat soil or clay To understand soil eating and its causes, researchers reviewed every documented case of soil eating in monkeys and apes They identified cases of soil eating in 136 species – over half of all monkeys and apes found around the globe – suggesting the behavior is more common than previously thought Evidence from the 287 articles reviewed also suggests that geophagy is a form of self-medication Geophagy may provide protection against disease-causing pathogens and supplement essential nutrients Although more research is needed, the work lays a foundation for future investigations into the causes and health impacts of geophagy The findings could also reveal new ways to promote the health of both wild and captive primate populations Pebsworth PA, et al..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource was created by Sarah Davenport in collaboration with Tina Williams as part of the 2019-20 ESU-NDE Digital Age Pedagogy Project. Educators worked with coaches to create Lesson Plans promoting both content area and digital age skills. This Lesson Plan is designed for 3rd grade General Education/Math.

For many years scholars have recognized that late nineteenth-century Durham, North Carolina makes an ideal case study for examining emancipation, industrialization, immigration, and urbanization in the context of the New South. "With its tobacco factories, textile mills, black entrepreneurs, and new college," the historian Syd Nathans observes, "Durham was a hub of enterprise and hope." By the early twentieth century, Durham became renowned for its vibrant entrepreneurial spirit. Both W.E.B. Du Bois and Booker T. Washington wrote articles for the national press about their visits with members of Durham's African-American community. After his visit in 1910, Booker T. Washington dubbed Durham the "City of Negro Enterprises." The Digital Durham website offers students, teachers, and researchers a range of primary sources with which they can investigate the economic, social, cultural, and political history of a post-bellum southern community. Letters from mothers to daughters, parents to children, and husbands and wives give insight into the domestic lives of some of Durham's elite citizens. Entries from Atlas Rigsbee's general store ledger together with data from the 1880 census provide a view into the social experience of those Durham citizens who have not left written documents. Taken together the new materials on Digital Durham touch on over 600 topics including African American business enterprise, the emergence of textiles, tobacco production and marketing, child labor, prohibition, evangelical revivalism, nineteenth-century medical practices, women's experience of childbirth, and public and private education. The holdings of the website provide access to a wide range of manuscript and printed materials from the 1870s through the 1920s. The site also features a new collection of maps that depict Durham from the late 1860s to the present day. Digital Durham offers its users a selection of manuscript letters taken from the Southgate-Jones family papers and James Southgate papers, accounts from Atlas M. Rigsbee's general store ledger, photographs, ephemera, census data, printed works as well as a rich collection of maps. The site also includes audio postcards created by Duke students in an undergraduate research seminar on the history of Durham and the New South. Additionally, the site includes resources for K-12 educators--a reference section with glossary of terms used in the 1880 census and lesson plans that tie to the North Carolina Standard Course of Study.

Digital ESL is a hands-on, paper-first course that teaches beginner English learners digital literacy through guided experimentation on their smartphones. It was designed to maximize hands-on learning opportunities both in and outside the classroom, utilizing students' own smartphone devices. Although originally created for teaching older adult (age 65+) beginner learners of English, it can be used with adults of any age.

Rural isolated Maori communities in Aotearoa face many obstacles in todays world. One of the many challenges encountered by the people in these communities is education. The young people living in isolated communities are disadvantaged in many ways due to the lack of technological resources and support that are available in towns and cities.
We live in a digital world, therefore, it is our responsibility to ensure our students experience the various opportunities out there.

This is a list of web based resources for exploring immigration and the lives of immigrants.

This informational text introduces students to the dinosaurs found near the polar regions and discusses the adaptations that allowed these dinosaurs to survive in a dark and cold environment. The text is written at a grade two through grade three reading level. This version is a full-color PDF that can be printed, cut and folded to form a book. Each book contains color photographs and illustrations.

This informational text introduces students to the dinosaurs found near the polar regions and discusses the adaptations that allowed these dinosaurs to survive in a dark and cold environment. The text is written at a kindergarten through grade one reading level. This version is a full-color PDF that can be printed, cut and folded to form a book. Each book contains color photographs and illustrations.

This informational text introduces students to the dinosaurs found near the polar regions and discusses the adaptations that allowed these dinosaurs to survive in a dark and cold environment. The text is written at a grade four through grade five reading level. This version is a full-color PDF that can be printed, cut and folded to form a book. Each book contains color photographs and illustrations.