Full course of Algebra 1 is presented online by Georgia Virtual Learning. Audio, video, text, games and activities are included to engage ninth grade students in learning.

Pennsylvania Assessment Anchors and Eligible Content eBook to assist educators in preparing student for the Keystone Exams.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"CCL2 is a small cell-signaling protein that recruits immune cells to sites of inflammation. CCR2 is CCL2’s receptor. Together, CCL2 and CCR2 create an inflammatory and immune-suppressive microenvironment, which promotes tumor growth and progression and induces resistance to anticancer drugs. A recent review highlights research on the therapeutic potential of targeting this so-called “CCL2-CCR axis”. Circulating levels of CCL2 are particularly elevated in individuals with obesity. Studies on men with prostate cancer suggest that inhibiting CCL2 signaling can significantly inhibit tumor growth and invasion. More work is needed to differentiate natural CCL2 levels in patients from tumor-derived CCL2 involved in the formation and spread of tumors, which could lead to new ways of attacking cancer and cancer resistance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Breast cancer is the most commonly diagnosed form of cancer, and it is also one of the most deadly. People who take progesterone for hormone replacement therapy or contraceptive purposes may be particularly at risk. A new study showed that disruption of the intricate balance between two cell signaling cascades may be at least partly to blame. Progesterone is thought to trigger cellular responses by binding to either classic nuclear receptors or non- classic membrane receptors. Researchers showed that the genes CCM1-3 (which form the CCM signaling complex) mediate the crosstalk between the signaling pathways associated with these two receptor types. The signaling network involving progesterone, the CCM complex, and membrane and nuclear receptors relies on an intricate feedback system to maintain homeostasis, indicating that excess progesterone can throw it out of balance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This module takes a look at the advantages of OER and the Creative Commons for both instructors and their learners. Both instructors and learners can enjoy using OER as well as creating it for use by others!

This is a Canvas shell for a course that meets the ASCCC definition for a course matching C-ID CDEV 100 Child Growth and Development.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Gastrointestinal stromal tumors (GISTs) are the most common malignant tumors in a type of gut tissue called mesenchyme. They’re caused by mutations that activate receptor tyrosine kinase (RTK) enzymes, and treatment with RTK inhibitors is initially successful, but over half of patients develop resistance, indicating a need for better treatments. Researchers recently investigated whether the drug THZ1, an inhibitor of the protein CDK7 that’s effective in other cancers, could help. They first confirmed that CDK7, which helps regulate the cell life cycle and gene transcription, was overexpressed in high-risk human GISTs. They also found that CDK7 overexpression predicted a poor outcome. However, low-dose THZ1 exerted pronounced anticancer effects in GIST cells both in vitro and in a mouse model. THZ1 also synergized with the RTK inhibitor imatinib to increase its efficacy..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Data Management Expert Guide
This guide is designed by European experts to help social science researchers make their research data Findable, Accessible, Interoperable and Reusable (FAIR).

You will be guided by different European experts who are - on a daily basis - busy ensuring long-term access to valuable social science datasets, available for discovery and reuse at one of the CESSDA social science data archives.

You can download the full DMEG for your personal study offline (DOI: 10.5281/zenodo.3820473). PDFs for every single chapter are also available for being printed as handouts for training.

The Council on Foreign Relations (CFR) presents a backgrounder on Al-Shabab; an Islamist insurgent group that remains capable of carrying out massive attacks in Somalia and surrounding countries despite a decade-long African Union offensive against the Islamist group. CFR Backgrounders provide an in-depth analysis on current political and economic issues.

The Council on Foreign Relation's (CFR) "Deforestation in the Amazon" InfoGuide provides a compelling look at the causes and consequences of deforestation in the Brazilian Amazon and is available online in English and Portuguese. CFR InfoGuides are a multimedia series to promote understanding of complex foreign policy issues.

The Council of Foreign Relations (CFR) InfoGuide on The Taliban examines the two Talibans, in Afghanistan and Pakistan, and the consequences for the region. CFR InfoGuides are a multimedia series to promote understanding of complex foreign policy issues.

The CJK Dictionary Institute was originally established for Chinese, Japanese, and Korean (CJK) resources, but has been expanded in recent years to other languages, including Arabic. The many Arabic resources available through the CJK Dictionary Institute include databases of proper nouns, transliteration programs, dictionaries, databases, articles related to transcription and translation issues, and more. The institute also provides software developers with dictionary data as well as consulting services.

Esta infografía da una visión general de la clonación. Explica la clonación como la creación de copias idénticas de organismos, células, virus o moléculas de ADN, destacando sus aplicaciones en investigación genética, producción de medicamentos, desarrollo de vacunas y terapia génica. Menciona hitos históricos y pioneros en el campo, como Robert Briggs, John B., así como Ian Wilmut con Keith Campbell. También describe el proceso de clonación genética para la creación de un ADN recombinante, en cinco pasos y presenta ventajas y desventajas, mencionando aspectos éticos y riesgos. Los autores son QFB Patricia Rosales-Flores, MC. Diana Lizzet Murrieta.León y Dra. Aracely López-Monteon

DEBIDO A QUE ACTUALMENTE SE ENCUENTRA EN REVISIÓN LA TESIS, EL DOCUMENTO ES PRIVADO POR EL MOMENTO,
PRÓXIMAMENTE SE DARÁ MAS INFORMACIÓN. GRACIAS.

La Tecnología de la Información (TI) siempre ha sido considerada un punto importante en las organizaciones empresariales, desde la perspectiva de los costos y de gestión. Es parte integral de la tecnología y los modelos de negocio de las empresas y las ha obligado a adaptarse a las nuevas estrategias de tecnología. Con los avances de infraestructura en la tecnología de la información y la comunicación, los nuevos modos de programación y los nuevos modelos en su uso; han llegado también nuevas formas de denominar los servicios de Internet. Factores como la mercantilización de hardware, software de código abierto, la virtualización, la globalización de la fuerza de trabajo y los procesos ágiles de TI han apoyado el desarrollo de nuevos modelos de tecnología y negocios. La computación en nube o Cloud Computing ofrece a las organizaciones más opciones en cuanto a cómo gestionar las infraestructuras, ahorrar costes, trabajar en equipo remotamente y delegar responsabilidades a proveedores de servicios Cloud o terceros, sin que los usuarios tengan que tener ningún conocimiento de la infraestructura que hay detrás.

La mayoría de las empresas se esfuerzan por reducir su coste del área de TI a través de los medios de virtualización. Esta demanda de reducir el costo ha dado lugar a la innovación de la computación en nube, ya que ofrece una reducción en los costos de administración así como reducción de costos de infraestructura. Los grandes beneficios del Cloud Computing permiten la adquisición de recursos computacionales de manera rápida, flexible y con un menor costo de implementación para los usuarios o empresas y es rentable para los proveedores, pues a pesar de presentar algunos riesgos, el poder trabajar con este nuevo tipo de tecnología permite al usuario ahorrarse tanto licencias, como la administración de servicios y de los equipos necesarios. Además de beneficios en términos de costo, el Cloud Computing puede presentar beneficios de seguridad ya que brinda a las empresas normas y estándares de seguridad de los más altos niveles internacionales. Incluso presenta beneficios ambientales y sociales. Todo gracias a la arquitectura conformada por los modelos con los cuales trabaja el Cloud Computing, denominadas por sus siglas: SaaS, PaaS e IaaS, las cuales corresponden al software, plataforma e infraestructura como servicios respectivamente.

El Cloud Computing se encuentra todavía en una etapa infantil y es una nueva tecnología para las micro, pequeñas, medianas o nuevas empresas. Existen pocas guías y marcos para una óptima adopción, la mayoría de ellos no se encuentran en la lengua española o no engloban todos los factores y cuestiones necesarias para generar confianza en esta tecnología. Por lo tanto, la mayoría de las empresas no están muy seguras en adoptar la tecnología. La presente tesis aborda el problema de confianza en la adopción y se discuten y analizan las barreras que se pueden presentar al adoptar la computación en nube en una empresa. Se presentan una serie de estrategias, una hoja de ruta y un marco que servirán como una guía para enfrentar los desafíos, cuestiones o factores en términos de costo, seguridad, confidencialidad, confianza, cumplimiento normativo, cumplimiento legal y cumplimento-TI, así como los factores organizacionales/humanos. En esta tesis se detallan exhaustivamente todos los temas referentes al Cloud Computing desde sus antecedentes, evolución, arquitectura, tecnología, modelos de negocio, modelos de servicio, modelos de despliegue, proveedores del servicio, etc. y así se logre un profundo entendimiento del paradigma de computación en nube. La metodología fue realizada siguiendo los lineamientos de diferentes estándares, normas, protocolos, estándares, certificados y mejores prácticas internacionalmente reconocidas respecto a la seguridad de la información en un entorno de TI ó enfocadas a entornos de Cloud Computing como: ISO/IEC 27001, ISO/IEC 27002, COBIT, ITIL, KMIP, TLS/SSL y CCSK. Esto logra una metodología con procedimientos adecuados para la adopción de Cloud Computing en las micro, pequeñas y medianas empresas que ya adoptan servicios de nube o están interesados en su adopción.

Palabras clave: Computación en Nube, Cloud Computing, SaaS, IaaS, PaaS, Costo, Cumplimiento, Seguridad, Confidencialidad, Confianza, Micro, Pequeñas y Medianas Empresas, Adopción, Estrategias.

Development of the Central Nervous System (CNS) includes development of the brain, spinal cord, optic and auditory systems, as well as surrounding supporting cells including ependymal cells, astrocytes, oligodendrocytes and microglia. Information within this page will exclude development of the Peripheral Nervous System (PNS) which includes nerve and ganglia formation.

Blood is supplied to the brain from a ventral arterial supply in all species; from a circle of arteries called the Circle of Willis (also called the cerebral arterial circle or arterial circle of Willis) which lies ventrally to the hypothalamus where it forms a loose ring around the infundibular stalk. Although the appearance of the circle of Willis is fairly constant amongst mammals, the sources of blood supply to the circle and the direction of flow around the circle are very species specific. Blood is supplied to the brain by the internal carotid artery in dogs and horses whilst in other domestic species the main blood supply is from branches of the maxillary artery.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"People can learn a lot from clinical trials -- like whether a new treatment works, whether it has serious side effects, or whether it would be cost-effective. How much a trial tells us, though, depends on what the researchers looked for and how they measured those outcomes. Unfortunately, people doing trials often don’t consult with patients -- or even with other researchers -- about what outcomes to focus on. With each researcher choosing their own outcomes to measure, comparisons between trials are difficult, and without input from patients, the most relevant ones are sometimes missed. It’s increasingly clear that selecting relevant outcomes is an important part of trial design, and that standardization could get more out of each trial, reduce waste in research, and move science and health care forward faster. To help, the COMET Initiative has written a new handbook on how to choose the most important outcomes..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.