This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Probiotic foods can help boost human health by promoting the growth of beneficial bacteria, but although probiotic bacteria can protect against infections with pathogens, little is known about the mechanisms underlying this interaction. In a new study, researchers evaluated the microbiome of a unique fermented kefir mixture. One of the predominant microbes found was the fungus Kluyveromyces marxianus, and a metabolite secreted by fungi – tryptophol acetate, which inhibits bacterial communication and virulence – was identified in the probiotic drink. Tryptophol acetate blocked the ability of the gut pathogen Vibrio cholerae to chemically sense bacterial density and form biofilms and altered the expression of genes associated with virulence. Although further studies are needed to fully understand the effects of probiotics on harmful gut bacteria, these results uncover a new cross-kingdom inhibition mechanism, where probiotic yeast prevent the growth of pathogenic bacteria..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Breast cancer is one of the most prevalent forms of cancer worldwide. Due to its complex pathology, breast cancer is often diagnosed late in its development—when it has already spread to other body parts. STAT3 is one protein known to play an important role in breast cancer, regulating gene expression within tumor cells to drive cancer progression, but growing evidence shows that STAT3 plays an equally important role outside of tumor cells—within the “tumor microenvironment”. Here, STAT3 suppresses immune defenses through interactions with various cells including myeloid-derived suppressor cells (MDSCs), macrophages, and dendritic cells (DCs). Interestingly, STAT3’s capacity to bypass these defenses relies on pathways for both immune suppression and activation. These findings make STAT3 an attractive target for anticancer therapies, which could help patients with breast cancer receive effective treatment as early as possible..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Welcome to this learning object on the Monarchy and the Lords in British Politics, 1783-1846. It has been developed for use on the module The Many Faces of Reform which explores key themes in the political history of Britain from the time of the French Revolution to the middle of the nineteenth century.

Poster showing a battle scene with trenches, a tank, and explosion. Forms part of: Willard and Dorothy Straight Collection.

This exercise is based on the recent formulation of a geobarometer based on the crystal structure of clinopyroxene (Nimis, 1995; 1998; 1999). This method relates structural parameters (e.g., the volumes of the unit cell and the M1 polyhedron) to the pressure at which the mineral crystallizes within basic and ultrabasic magmas.

In this exercise, students are guided into the American Mineralogist Crystal Structure Database to retrieve and download published crystal structure data for viewing in either the CrystalMaker or XtalDraw visualization software packages. The students are instructed on how to examine the structures to determine pressure-sensitive crystallographic parameters and are asked a series of questions related to what they learn.

(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)

Es una presentación dirigida a todos los agentes de enfermería, especialmente aquellos agentes que se desempeñan en la Unidad de Cuidados Críticos Adultos. Se trata sobre todos los cuidados que los enfermeros deben aplicar en la pronación de un paciente/usuario intubado conectado a ventilación mecánica. Se define que es el decúbito prono, cuales son los beneficios, las contraindicaciones, los cuidados enfermeros pre-rotación, en la rotación y post-rotación.
El contenido bibliográfico esta expresado en la última filmina, en un elemento interactivo.

This module includes three units exploring the connections between adolescent development, the science of learning, and culturally responsive pedagogies. It is meant to make the case that K-12 teachers must not ignore the impact and value of culture as a dimension of development and factor in learning processes. The module culminates in an exploration of how the Universal Design for Learning (UDL) framework overlaps with principles of CRT (Culturally Relevant Teaching).

According to Montenegro & Jankowski, 2017, culturally responsive assessment is an assessment that is mindful of the student populations the institution/school serves, using language that is appropriate for all students when developing learning outcomes, acknowledging students’ differences in the planning phases of an assessment, and being intentional in using assessment tools and results to improve learning for all students.  This module will provide explicit instructions to guide your thinking about the relationship between assessment and instruction.The goal of this course is to introduce K-12 Educators and Higher Education faculty to using standards and assessment alignment to support all types of learners.  

The artist portrays congressional efforts to pass the Crittenden Compromise as an antidote to Republican intransigence on the slavery issue. (For an earlier anti-North satire relating to the compromise, see "Congressional Surgery. Legislative Quackery," no. 1860-44.). Three well-dressed men (probably members of Congress) attend a sick man, who wears a dressing gown and holds a document inscribed "Republican Platform No Compromise." Together they pull the invalid from his chair and struggle to force an oversized pill "Crittenden Compromise" down his throat, pushing it with a "Petition of 63,000." A box of "Constitutional Remedies" (containing more giant pills) is on the floor nearby. The door to the room stands open at right.|Ent'd According to act of Congress 1861.|Published by Benj. Day 48 Beekman St. N.Y.|Signed: BDay del (Benjamin H. Day, Jr.).|Title appears as it is written on the item.|Weitenkampf, p. 130.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1861-1.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Real-world data and real-world evidence are terms widely used in the field of health care. In fact, various stakeholders are showing increasing interest in using real world data and real world evidence. Pharmaceutical companies, for example, use real world data for various purposes—from the early stages of development to post-launch. One hot topic focuses on using real world data and real world evidence to support regulatory decision making to deliver drugs faster to patients with high medical needs. This has been the subject of active discussion in the US, Europe, Japan and other countries, leading to regulatory reform and improvement of the implementation environment. However, there are barriers to the regulatory acceptance and use of both real world data and real world evidence. Real world data should be evaluated not only for quality but also for data relevance. There is a lack of universally accepted methodological criteria..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

You may have already had to digitize a curve from an original document in the form of an image, which is quite tedious to do by hand.

To facilitate the digitization of curves, we have created a small utility that allows you to display on the screen the previously scanned image of a graph, then to very easily record the points of the curves you are interested in (up to 2000).

One of two prints by "HD" (identified by Weitenkampf and others tentatively as Henry Dacre) based on incidents during President Van Buren's visit to the resort at Saratoga Springs, New York, during the summer of 1839. (See also "The Meeting at Saratoga" no. 1839-4.) Although Van Buren is known to have stayed at Saratoga on his tour of New York State, it is not clear to what degree Dacre's scenes are imaginary or contrived for satirical effect. Here Martin Van Buren is snubbed by the widow of former political rival DeWitt Clinton. In a room filled with elegantly dressed men and women, Van Buren says to Mrs. Clinton, "Stay Madam, I would beg some words with you." Mrs. Clinton, turning away, is asked by her companion, "Mrs. C...... why did you not speak to him, when he look'd so very Pleasant?" To which she responds, "I! I! speak to the ........ who persecuted my husband to the day of his Death!" Mrs. Clinton's refusal to speak to Van Buren at Saratoga, on the grounds that he had allegedly dissuaded former President Jackson from visiting her, was widely reported in the New York press. |Lith. of H.R. Robinson, 52 Cortlandt St.|Signed with monogram: HD (Henry Dacre?).|Title appears as it is written on the item.|Weitenkampf, p. 59.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1839-3.

Figurative portrayal of Whig opposition to the independent treasury or subtreasury system conceived by Jackson and implemented by Van Buren and the Democrats. In a large tree is a nest labeled "Sub Treasury" in which sits an alarmed hen, Andrew Jackson, who says, "Woodman spare that tree!! By the Eternal dont cut it down." Falling from the tree is a crow with Van Buren's head who exclaims, "I'll never trust to Hickory agin, but go and roost among the "Kabbitches" at Kinderhook." The tree is being felled by Harrison, who wields an axe "Reform," and says, "I used to be a pretty good axe-man when I first lived in a log cabin! I think there's enough left of the old stuff yet to hew down this tree!" Henry Clay and Daniel Webster are pulling it down with a rope. Clay: "Down with it! it has overshadowed the land long enough, and poisoned every thing with its noxious exhalations!" Webster: "Pull together and down it must come!" |Entered . . . 1840 by John Childs.|Published by John Childs, 90 Nassau St. New York.|Signed with monogram: EWC (Edward Williams Clay).|The print was deposited for copyright on September 24, 1840. |Title appears as it is written on the item.|Davison, no. 137.|Weitenkampf, p. 65.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1840-57.

This book on Cybersecurity is written for beginners. No college degree is required. Cybersecurity covers a broad spectrum of topics. This book intends to ease the initial learning curve using associable analogies in normal life and graphical and guided exercises. Completing the Cybersecurity study in this book can be accomplished in a self-paced learning manner outside of a classroom.

It is hoped that self-paced learning and/or the teaching of this book at various institutions will open the doors to a broader audience in their career development towards the job-rich cybersecurity industry. Further, it is hoped that by demystifying cybersecurity, people will build up their interests and confidence in transitioning into the cybersecurity industries from whatever field they are working in today.

Have you ever felt uneasy or even dreadful after losing a USB flash drive that might contain sensitive information or data about your business?

This presentation will give you a tool to put you at ease when backing up a large number of files and data to a USB flash drive or stick. The tool is relatively easy to use on a USB drive, is based on encryption technology, and protects your business data from the prying eyes.

Attendees will learn about the following topics:
- A brief introduction to data encryption.
- A few encryption tools for a novice user.
- Demonstration on how to use an encryption/decryption tool called VeraCrypt to protect the data on a USB
flash drive.
- Pros and cons of encryption/decryption technology.

The Payment Card Industry (PCI) has created an industry-wide digital security standard. All companies, large and small, that deal with customers’ credit card information, must comply with the PCI Digital Security Standard. What can small business owners do to manage the compliance risks, yet to be cost-effective?
 
Topics to be covered include:

- What is PCI/credit card data security?
- Why do small businesses need to plan for PCI security compliance?
- Tools and tips to check PCI compliance of your credit card payment processor or payment gateway provider
and website hosting service provider.
- IT audit requirements and stages for PCI compliance.
 
Presentation Time: 50 minutes plus 10 minutes Q&A.
Presentation Recording: Webinar recorded by SCORE (www.score.org). SCORE is a non-profit organization. URL link: https://drive.google.com/file/d/1HI7iFrTo8xX7o1C_OmmzybpSo6X2Op29/view?usp=drive_link

The Health Insurance Portability and Accountability Act of 1996 (HIPAA) is a federal law that requires the creation of national standards to protect sensitive patient health information from being disclosed without the patient’s consent or knowledge. The US Department of Health and Human Services (HHS) issued the HIPAA Privacy Rule to implement the requirements of HIPAA. The HIPAA Security Rule protects a subset of information covered by the Privacy Rule (URL: https://www.cdc.gov/phlp/publications/topic/hipaa.html).

Small businesses that deal with healthcare information must comply with HIPAA. What can small business owners do to manage the compliance risks, yet to be cost-effective?
 
Topics to be covered include:
- What are the business requirements for HIPAA security?
- What stages of IT audit do small businesses need to plan for HIPAA security compliance?
- What technology and tools can be used to protect HIPAA-related data and to assure compliance?
 
Presentation Time: 50 minutes plus 10 minutes Q&A.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The protein eIF6 is involved in ribosome formation and mRNA translation and is essential for the growth and reproduction of cells, including cancer cells. However, eIF6’s role in oral squamous cell carcinoma (OSCC) remains unclear. To learn more, researchers recently analyzed eIF6 in 233 OSCC samples and in OSCC cell lines. They found that cytoplasmic eIF6 expression was abnormally high in OSCC tissues and was associated with tumor size and clinical grade. Upregulating eIF6 promoted OSCC cell growth, migration, and invasion in vitro and enhanced tumor growth in vivo. eIF6 also encouraged epithelial-mesenchymal transition (EMT), a process necessary for cancer cell migration, in OSCC cells, but depletion of eIF6 (with sh-eIF6-2) suppressed the cancer-enhancing effects. Mechanistic studies revealed that eIF6 exerted its tumor progression-promoting effects by activating the AKT signaling pathway, and further experiments confirmed that eIF6 and AKT directly interacted in the cytoplasm..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Our cells’ behavior depends on their underlying structure – the cytoskeleton. A dynamic network of protein filaments and tubules, the cytoskeleton drives motion. It is also central to cell development – and cancer. One protein at the center of cytoskeletal events is Merlin. Like other FERM-family proteins, Merlin mediates interactions between actin and transmembrane receptors, translating signaling into motion, adhesion, and growth regulation. Because it regulates such essential pathways, Merlin has a dual role in human biology. Its connection to the cytoskeleton is essential for embryonic development. and the signaling pathways it orchestrates are required for cell differentiation in later stages of development. At the same time, Merlin also maintains appropriate cell signaling levels and growth, preventing cancer progression. Further studies will shed light on Merlin's role in different contexts, improving our understanding of therapeutic strategies for disorders of both development and cancer..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.