Luteinisation occurs after ovulation and the collapse of the follicle. The number of corpora lutea formed in the ovary at any one time is directly proportional to the number of oocytes ovulated. Therefore many corpora lutea will be visible on the ovary of polytocous animals. During Luteinisation there is an increase in both the size and weight due to hyperplasia (increase in cell number) and hypertrophy (increase in cell size) within the developing corpus luteum.

"Salt River," the fictitious river of political doom, is charted here as a meandering stream of Democratic misfortunes. The chart was purportedly "prepared by Father Ritchie," i.e., Democratic editor and Polk administration spokesman Thomas Ritchie. Swipes are taken at the Tariff of 1846, Polk's Vice President George M. Dallas, Martin Van Buren, and 1848 Democratic presidential nominee Lewis Cass. The river winds upward from the Ohio River (Ohio was a Democratic stronghold in 1848) to the Lake of Oblivion with an island on which sits the "Mansion of Despair." The "Fast Sailing Steamer Free Trade," captained by Lewis Cass and piloted by Ritchie, sets out on the "Slough of Despond" below (one of the landmarks in John Bunyan's "Pilgrim's Progress&1). The ship approaches a fork, from which the "Old Fox Branch" on the right leads to "Cabbage Point" and the home of Martin Van Buren. Van Buren can be seen sitting in a rowboat on the river complaining, "Hard work this all; your fault 'John,' with your D--d Free Trade." His son John, a Free Soil party leader and campaigner, encouraged Van Buren's bid for the party's presidential nomination in 1848. On the left Salt River continues past the "Sub Treasury Bluffs," "Noise and Confusion Shoals," "Two Face Points," and "Irish Relief Shoal" (a reference to Democratic support for anti-British insurgents in Ireland), to another fork, "Prince John's Creek." Here John Van Buren walks along the shore and calls, "Good bye Dad! We could not Gull the People." The main branch of the river continues to "Pillow's Cemetery" (named after Gen. Gideon Pillow, conspirator against popular Mexican War commander Winfield Scott and a friend of James K. Polk), "One Seal Island" (?), "Casting Vote Point," and "St Anna Pass." The last is named after Mexican president and commander Santa Anna, whom the Polk administration returned from exile only to see him lead the war against the Americans. On Lake Oblivion is a small ferry boat heads toward the shore at upper right where it will connect with a train named "Tariff [of 18]42," bound for Washington. On the left is a funerary monument "In Memory of Dallas," a memorial to Vice President and former Pennsylvania senator George M. Dallas. Many of Dallas's fellow Pennsylvanians viewed him as a traitor to the state's interests in his support of the Tariff of 1846, which supplanted the popular 1842 tariff.|Title appears as it is written on the item.|Weitenkampf, p. 97.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1848-26.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The ribosomal RNA (rRNA) gene approach to sequencing genetic material has revolutionized microbiome science. But it isn’t perfect. The method relies on the assumption that counts of rRNA genes translate into microbial abundance. Exceptions to that rule, however, are known, such as the observation that rRNA gene counts can be higher in fast-growing microbes. Now, researchers report a new relationship between rRNA genes and cell volume that could help correct for biases inherent to microbiome studies. An analysis of previously reported data showed that the number of 16S or 18S RNA genes per cell follows an allometric power law of cell volume. Applying this relationship to a dataset for bacteria found in intertidal rocks allowed for more accurate biovolume and cell count distributions to be estimated for all taxa detected. The development of more comprehensive cell-size databases could help strengthen the bias-correcting relationship and boost the power of current microbiome analyses..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"How does a person experiencing anesthesia lose consciousness? Despite billions of surgeries, scientists still don’t fully understand what happens in the brain when a patient goes under. New research in the journal Anesthesiology, however, provides a few more clues. Working in a group of patients with epilepsy, scientists used a new information measure to evaluate electrocorticography data -- and found that with anesthesia, there is a reduction in information integration and network connectivity. The team recorded electrocorticograms, or intracranial E-E-Gs, from nine patients who were anesthetized predominantly with propofol and underwent surgical treatment for epilepsy in China. To assess information integration, the team used a measure called [genuine permutation cross mutual information], or G-P-C-M-I. In an earlier study, they found the measure performed better than others using scalp EEG recordings..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Este guia prático ensina o passo-a-passo para a construção da Cortina Térmica Sustentável. Ela foi feita com material de descarte da merenda escolar, caixa de leite, e reutilizado para construir a cortina, que tem como função refletir a luz solar para fora da sala e amenizar o calor interno. Foi um resultado promissor e que resolveu um problema coletivo escolar e ambiental. Tem fácil replicação e com custo baixo. Ganhou premiação na MILSET BRASIL em Fortaleza e depois credencial internacional para se apresentar na Expo - Sciences International - ESI 2019, em Abu Dhabi, nos Emirados Árabes.Foi um produto Educacional resultante da pesquisa de mestrado da autora, Giselly Alencar, com Orientação da professora Valéria Sandra de Oliveira Costa e Patrícia Smith Cavalcante e com colaboração do professor Marcelo Cairrão Araujo Rodrigues - UFPE. 

A series of four posters showing the scale of the Universe, intended for the walls of science classrooms in secondary schools.

Sort different objects found in space based upon their size, distance and age!

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Hepatocellular carcinoma (HCC) is an aggressive, treatment-resistant liver cancer. One factor associated with poor prognosis in patients with HCC and other cancers is elevated levels of the enzyme WIP1. WIP1 removes phosphate groups from other proteins and is involved in many potentially pathogenic processes. Researchers recently explored WIP1 as a target for HCC treatment. In both patient databases and cell culture experiments, WIP1 was consistently elevated in HCC cells compared to normal liver cells. Further experiments revealed that inhibiting WIP1 slowed cancer progression by increasing DNA damage in cancerous cells, thus killing them. With less WIP1 available, more of the key homologous recombination repair protein H2AX was phosphorylated and impaired, allowing damage to accumulate in HCC cells. Cells from cancers with impaired homologous recombination repair, like breast cancer, can be killed by inhibiting another enzyme, PARP..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Glioblastoma is a highly malignant and frequently occurring tumor of the central nervous system. Recurrences are extremely common and often resist chemotherapy and radiotherapy, so new treatment options are needed. Immune checkpoint inhibitor immunotherapies successful in treating other types of cancer have been tried, but glioblastoma has resisted them. An effective therapeutic strategy must account for 3 things: glioblastoma's ability to evade immune system surveillance; its location behind the blood-brain barrier, which generally shields it from chemical compounds; and its inherent resistance due to its mutations and the variety of cells it contains. A tumor vaccination approach, which targets innate features of glioblastoma cells, has shown some promise. Vaccines based on peptides, cells, DNA, and mRNA have been developed. Unfortunately, few trials have reached phase III, because most patients with recurrent glioblastoma are very ill..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Prostate cancer is the most common cancer and the second most common cause of cancer-related death in men. The standard treatment is androgen deprivation therapy (castration), but prostate cancer becomes resistant to this treatment over time. Targeting the androgen receptor seems logical but has had little effect on patient survival so far. Intriguingly, a chemical related to estrogen, 4-hydroxyestradiol (4-OHE2), also promotes cancer occurrence and progression. A recent study examined the role of 4-OHE2 in castration-resistant prostate cancer (CRPC) cells. The protein CYP1B1 is involved in the production of 4-OHE2, and CYP1B1 was found to be elevated in CRPC cells. In addition, 4-OHE2 promoted ERα transcriptional activity in CRPC cells. 4-OHE2 promoted tumor formation through the IL6-STAT3 pathway, which sends inflammatory signals important in many cancers..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A recent case study reports the apparent benefits of classical homeopathy for people with varying severities of psoriasis. Their conclusion: a more holistic approach that goes beyond skin clearance might be one solution for certain sufferers of the disease. Psoriasis is a chronic inflammatory disease affecting more than 125 million people worldwide. In addition to its effect on the skin, psoriasis can take a psychological toll due to its appearance. And if tied to systemic inflammation, it can even cause serious morbidity or death. Modern treatment options for psoriasis, such as the use of biologics, are designed to block the inflammatory factors that give rise to disease symptoms. While generally effective, these agents can actually weaken a patient’s immune system, making their prolonged use risky. That has many researchers exploring alternative routes for treatment that go beyond clear skin to achieve a better quality of life..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Non-small cell lung cancer, or NSCLC, is the leading cause of cancer-related death worldwide. While radiation therapy can be powerful against NSCLC, lung cancer cells may develop resistance. A new study traces this “radioresistance” to a protein that interacts with estrogen receptor ERβ. ERβ is known to alter the radiation sensitivity of certain breast cancer cells. So researchers wondered: Might ERβ might do the same in cells affected by NSCLC? To find out, they blasted lab-grown cells with gamma rays and tracked ERβ’s behavior. Results showed that radiation indirectly activated ERβ-based defenses through the protein CLPTM1L. CLPTM1L is abnormally expressed in the cytoplasm of many human lung cancer cells, especially in cells affected by NSCLC. A closer look revealed that radiation caused CLPTM1L to migrate to the nucleus of cancer cells, where it gained direct access to ERβ’s genetic machinery and its ability to induce radioresistance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Poster showing South Broad Street and City Hall decorated with pennants and flags.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Genetics can affect many aspects of human health, in part by influencing the composition of the gut microbiome. The associations between genetic variants and individual microbial taxa are often investigated with genome-wide association studies (GWASs). However, typical GWASs have low statistical power, because they require extensive multiple testing and can’t account for inherent data structure. To help solve this problem, researchers recently developed a new approach: a covariate-adjusted kernel RV (KRV) framework. This framework compares pairwise similarity in genetic profiles to pairwise similarity in microbial profiles therefore reducing the multiple testing burden without obscuring the data structure. In simulation studies, the KRV framework had greater statistical power than other microbiome GWAS approaches in a range of scenarios..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Active learning modules to help students understand the role of cover crop species selection and design of mixed species cover crop plantings on multiple ecosystem services. Our current goal is to integrate lessons-learned from 8 years of research and extension activities into undergraduate education modules that can be widely distributed. Students completing these modules would be able to describe why cover crops are used, how different species of cover crop affect an array of ecosystem functions, how mixtures can be used to increase the multifunctionality of cover cropping systems, and factors that control mixture growth across sites. If the modules are delivered in the following order then these concepts build sequentially.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Alzheimer’s disease is a progressive brain disorder that gradually destroys memory and thinking skills Every year, the number of people affected by the disease continues to grow That has some researchers looking to the fruit fly for answers One team has found that linking two parts of the cell closer together may help Linking the endoplasmic reticulum, which forms proteins and stores calcium to the mitochondria, which power the cell can actually improve motor function in fruit flies and help them live longer This technique works in flies with brain plaques similar to those found in humans with Alzheimer’s disease Part of the reason could be improved access to calcium Forcing the organelles together helps calcium migrate more easily from the endoplasmic reticulum to the mitochondria This sends the mitochondria into overdrive because calcium acts as a lubricant for the mitochondrial machinery that pumps out energy So easy access to calcium means more energy output Clarifying how that transl.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This art history video discussion examines Lucus Cranach the Elder's "Adam and Eve", 1526, oil on panel (Courtauld Gallery, London).

Cranial nerves are those nerves which arise from the brain and brain stem rather than the spinal cord. Nerves arising from the spinal cord are the peripheral nerves. There are 12 pairs of cranial nerves and these pairs of nerves passage through foramina in the skull, either individually or in groups. Cranial nerves are traditionally referred to by Roman numerals and these numerals begin cranially and run caudally.

12 Cranial Nerves made easy.anatomy and physiology of the 12 cranial nerves made easy with mnemonics.