In this seminar you will create images of the biologically important structures …
In this seminar you will create images of the biologically important structures of the cell membrane. The pictures will be translated to function. You will practice the terminology of these structures to associate their importance in the function of the cell membrane. The inquiry lab will allow you to design a model of the limitations of cell growth due to the cell membrane using water balloons.StandardsBIO.A.2.2.3 Compare and contrast the structure and function of carbohydrates, lipids, proteins, and nucleic acids in organisms.BIO.A.4.2.1 Explain how organisms maintain homeostasis (e.g., thermoregulation, water regulation, oxygen regulation).BIO.A.4.1.3 Describe how endoplasmic reticulum, Golgi apparatus, and other membrane-bound cellular organelles facilitate transport of materials within cells.BIO.A.4.1.2 Compare and contrast the mechanisms that transport materials across the plasma membrane (i.e., passive transport -- diffusion, osmosis, facilitated diffusion; active transport -- pumps, endocytosis, exocytosis).BIO.A.4.1.1 Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell.
In this seminar, you will discover that proteins need additional processing after …
In this seminar, you will discover that proteins need additional processing after translation. You will determine what you know and what you need to know through a knowledge inventory and quiz. You will try your hand at gaming to learn protein modification and structure, or build an RNA molecule to create proteins.StandardsBIO.B.2.2.1 Describe how the processes of transcription and translation are similar in all organisms.BIO.B.2.2.2 Describe the role of ribosomes, endoplasmic reticulum, Golgi apparatus, and the nucleus in the production of specific types of proteins.BIO.B.2.3.1 Describe how genetic mutations alter the DNA sequence and may or may not affect phenotype (e.g., silent, nonsense, frame-shift).
Life as an emergent property of networks of chemical reactions involving proteins …
Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"The liver has a unique ability to regenerate after damage due to injury or disease. This regeneration relies primarily on the proliferation of hepatocytes, the main cells in the liver. Hepatocytes and many other liver cell types, including endothelial cells, bile duct cells, and immune cells, interact in a coordinated manner to enable repair. For example, liver endothelial cells promote the hepatocyte proliferation that’s necessary for regeneration, and hepatocytes activate a signaling pathway that promotes blood vessel growth to nourish the new liver tissue. If hepatocyte proliferation is impaired, an alternate pathway can direct liver regeneration through transformation of bile duct cells into hepatocytes. Liver endothelial cells promote this conversion process, helping to build the hepatocyte population. while connective tissue–forming cells encourage bile duct cell growth and proliferation, ensuring an ample supply of these cells..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Membrane-enclosed extracellular vesicles, exosomes, are a critical part of intercellular communication in many biological systems. However, the regulation and biological implications of exosome excretion and uptake remain unclear. A recent study examined the role of cellular retinoic acid (RA) binding protein (Crabp1) in exosome secretion and its relationship to receptor interacting protein 140 (RIP140), a pro-inflammatory transcription co-regulator. Crabp1 knockout mice consistently showed deficits in negative control of exosome secretion and exhibited increased vulnerability to systemic inflammation. Crabp1 knockout mice had significantly elevated RIP140-containing exosomes in their blood and cerebrospinal fluid. Cell culture experiments suggested that exosome secretion can transfer RIP140 from neurons to macrophages, where it promotes macrophage inflammatory polarization..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
Two or three weeks of the course are dedicated to studying diagenesis. …
Two or three weeks of the course are dedicated to studying diagenesis. Lectures start with a general definition of diagenesis, the range of conditions under which it occurs, and examples of diverse diagenetic environments and features. I use rice crispy cereal and rice crispy treats to introduce cement (the marshmellow is the cement that "glues" the rice krispies together). I also incorporate basic hydrogeology to show how pores filled with (or partially filled with) groundwater provide both the space and the material for cementation. As part of this lecture, I show the students various rock samples and photomicrographs in which they can see cement examples. I outline the different cement minerals and shapes and how they can be used to interpret past diagenetic conditions (eg., gravitational "pendant" calcite cements indicate that the host sediment was once in a vadose zone with groundwater rich in calcium and carbonate). I also discuss types of pores during these lectures and the ways that pores form. We also discuss criteria for recognizing cements. After two one-hour lectures about cements, we have a lab exercise in which the students are given ~10 samples (including hand samples and thin sections) and asked to sketch and describe the cement types. The next one-hour lecture focuses on neomorphic processes and their products, including replacement, recrystallization, and polymorphic transition. As part of the lecture, we look at photomicrographs and hand samples that illstrate various neomorphic features, such as replacement dolomite and replacement chert. We establish criteria for distinguishing cements from neomorphic fabrics. This lecture is followed by a lab exercise that presents the students with ~10 rocks and thin sections and asks them to sketch and identify neomorphic fabrics. This lab is follwed by another one-hour lecture on compaction features, dissolution evidence, and determining paragentic sequences. If I am short on time, that is all I do for diagenesis. However, ideally, I continue with a lecture focused on the "dolomite problem" and some case studies of other types of diagenesis, as well as a third lab assignment that combines cementation, neomorphism, compaction, dissolution, and paragenetic sequences. As part of this section, I also try to incorporate examples of methods other than petrology (eg., fluid inclusion studies, stable isotope studies, dating) that are used for diagenetic studies. Later in the course, we take several field trips in which the students examine diagenetic features.
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Studying rock types, weathering processes and human history in a cemetery. (Note: …
Studying rock types, weathering processes and human history in a cemetery.
(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)
In this activity, students view a Quicktime video animation based on data …
In this activity, students view a Quicktime video animation based on data from the North American Volcanic and Intrusive Rock Database (NAVDAT) to learn about the history of volcanism in the western U.S. during the last 65 million years. Students are guided through the complex data-rich animation with a series of instructions and study questions which highlight time-space-composition relationships and link to plate tectonics.
(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"_Clostridioides difficile_ infection (CDI), the most common hospital-acquired infection in the U.S., can cause severe diarrhea and even death, and more than 15% of infected individuals experience recurrent infection within 8 weeks. CDI is related to gut microbiome imbalance, but the factors that influence recurrence are not well understood. To identify potential predictors of recurrence, researchers sequenced and metabolically profiled the gut microbiomes of 53 patients with CDI over time. Compared to patients with no recurrence, patients with recurrent CDI had slower recovery of gut microbial diversity, and depletion of important anaerobic microbes, such as certain _Clostridium_ species. The patients with recurrent CDI also had delayed recovery of microbial metabolites in the gut, which was likely associated with dysfunction of the microbiome or of the host tissue..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This is a homework problem for Chapter 2 that involves concepts including: …
This is a homework problem for Chapter 2 that involves concepts including: step length, step frequency, walking speed, and Froude number, takes less than 15 minutes to complete by hand.
This activity engages learners in exploring the impact of climate change on …
This activity engages learners in exploring the impact of climate change on arctic sea ice in the Bering Sea. They graph and analyze sea ice extent data, conduct a lab on thermal expansion of water, and then observe how a scientist collects long-term data on a bird population.
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