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Blaze by Intabio: An imaged cIEF-MS platform for
biopharmaceutical quality attribute monitoring
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Biopharmaceuticals, protein-based drugs manufactured by living cells, are some of the most powerful and effective drugs leading the fight against numerous diseases. But producing them is a notoriously difficult business. Growth conditions, purification procedures, and formulation requirements can unintentionally change the protein structure of these drugs, altering their efficacy and toxicity. Testing for these modifications is therefore crucial. But current methods are cumbersome and don’t provide the throughput and real-time analytics that today’s rapidly growing biopharma industry desperately needs to control their development and manufacturing efforts. Now, there’s a solution. Introducing Intabio’s Blaze system. The Blaze platform performs a comprehensive analysis of biopharmaceutical product quality with 100 times higher throughput than traditional approaches..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Biology
Engineering
Health, Medicine and Nursing
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/23/2020
BlendEd Learning Best Practices: ELA 10: To Kill a Mockingbird
Conditional Remix & Share Permitted
CC BY-NC-SA
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This resource was created by Jen Kastanek in collaboration with Lauren Rabourn as part of the 2019-20 ESU-NDE Digital Age Pedagogy Project. Educators worked with coaches to create Unit Plans promoting BlendEd Learning Best Practices. This Unit Plan is designed for Grade 10 and English Language Arts.

Subject:
Literature
Reading Literature
Material Type:
Assessment
Homework/Assignment
Lesson Plan
Reading
Teaching/Learning Strategy
Unit of Study
Author:
Lauren Rabourn
Date Added:
06/02/2020
BlendEd Learning Best Practices: ELA 11-12: Independent Choice Novel Project
Conditional Remix & Share Permitted
CC BY-NC-SA
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This resource was created by Brandi Edmond in collaboration with Lauren Rabourn as part of the 2019-20 ESU-NDE Digital Age Pedagogy Project. Educators worked with coaches to create Unit Plans promoting BlendEd Learning Best Practices. This Unit Plan is designed for Grades 11-12 and English Language Arts.

Subject:
Literature
Reading Literature
Material Type:
Assessment
Homework/Assignment
Lesson Plan
Reading
Teaching/Learning Strategy
Unit of Study
Author:
Lauren Rabourn
Date Added:
06/02/2020
Bless Me, Ultima by Rudolfo Anaya - Reader's Guide
Read the Fine Print
Educational Use
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One of the most respected works of Chicano literature, Rudolfo Anaya tells the story of Antonio Juan Marez y Luna, a young boy who grapples with faith, identity, and death as he comes of age in New Mexico. The Big Read Reader's Guide deepens your exploration with interviews, booklists, timelines, and historical information. We hope this guide and syllabus allow you to have fun with your students while introducing them to the work of a great American author.

Subject:
Arts and Humanities
Literature
Material Type:
Reading
Provider:
National Endowment for the Arts
Provider Set:
The Big Read
Date Added:
08/05/2013
'The Blob' - The Story of the Pacific Heatwave
Read the Fine Print
Educational Use
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This video explores the affect on seabirds of a three year ocean warming event (2013-16) in the NW Pacific. With ocean warming, a massive die off occurred based on the decline of food resources.

Subject:
Applied Science
Biology
Career and Technical Education
Ecology
Environmental Science
Environmental Studies
Life Science
Physical Science
Material Type:
Diagram/Illustration
Reading
Provider:
CLEAN: Climate Literacy and Energy Awareness Network
Provider Set:
CLEAN: Climate Literacy and Energy Awareness Network
Author:
Ascentios
Ben M. Collins
Date Added:
11/29/2020
Blocking heat shock protein reduces signs of chronic myeloid leukemia
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Chronic myeloid leukemia, or CML, is a rare, slow-growing cancer of the bone marrow. It’s caused by the protein Bcr-Abl, which builds up and causes cells to grow and divide out of control. Now, researchers have identified one of Bcr-Abl’s close molecular partners and figured out how it might be forced to abandon Bcr-Abl and stop its deadly buildup. Experiments revealed that Bcr-Abl interacts with the heat shock protein HSP90AB1. HSP90AB1 supports Bcr-Abl’s rampant and deadly buildup in cells by blocking its entry into the nucleus. By deactivating HSP90AB1 in cultured cells with the antibiotic tanespimycin (17AAG), the researchers discovered that they could lock Bcr-Abl in the nucleus, reducing the spread of CML and programming CML cells for death. While more work is needed to understand how these processes play out in humans, these findings support the development of heat shock protein inhibitors as viable treatments for CML and other Bcr-Abl-associated malignancies..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/14/2021
Blog Post_Reflection on Networking Across Cultures.
Conditional Remix & Share Permitted
CC BY-SA
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This blog post shares the personal experiences of an educator reflecting on their networking journey from India to the USA. It begins with an event description of networking at a college festival in India, highlighting the importance of community ties and initiating conversations. The narrative then shifts to a first-year master's student attending a professional networking event in the USA, emphasizing the value of preparation, leveraging digital tools like LinkedIn, and being proactive in follow-ups.

Subject:
World Cultures
Material Type:
Case Study
Reading
Author:
Pooja Potdar
Date Added:
07/27/2024
Blogpost - Are Fast Plants Genetically Engineered Plants?
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CC BY-NC-SA
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This blog post from the Fast Plants Team addresses the question "Are Wisconsin Fast Plants Genetically Engineered Plants?". This post describes the origins of Fast Plants (they are the result of conventional plant breeding, not genetic engineering), defines terms related to plant breeding and genetic engineering, and describes the selection criteria that led to the Wisconsin Fast Plant.

Subject:
Genetics
Life Science
Material Type:
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Hedi Baxter Lauffer
Jackson Hetue
Date Added:
05/25/2023
Blogpost - Biological Environment: Growing Healthy Fast Plants
Conditional Remix & Share Permitted
CC BY-NC-SA
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Read this blog post for background information about the relationship between the biological environment and life processes and systems in Fast Plants. Growing healthy Fast Plants is easy if you understand how the environment can affect growth and development. Three broad categories of environmental factors influence how an individual plant matures through its life cycle:  1) the physical environment, 2) the chemical environment, 3) the biological environment.  Based on this information about standard conditions for optimal Fast Plants growth, one could easily design a wide variety of controlled experiments. Questions naturally arise while reading about optimal conditions that could be investigated by designing an experiment to how varying one condition affects growth, development and/or reproduction. This blog post is part of a series explaining how key environmental factors–physical, chemical, and biological–can impact the growth of Wisconsin Fast Plants.

Subject:
Agriculture
Career and Technical Education
Material Type:
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Hedi Baxter Lauffer
Date Added:
05/25/2023
Blogpost - Can bee sticks sting?
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CC BY-NC-SA
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This blog post from the Fast Plants team addresses the question "can bee sticks sting?" (no, bee sticks cannot sting) and provides information on the use of bee sticks for pollination of Fast Plants in the classroom.

Subject:
Agriculture
Career and Technical Education
Material Type:
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Hedi Baxter Lauffer
Date Added:
05/25/2023
Blogpost - Chemical Environment: Growing Healthy Fast Plants
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating
0.0 stars

Read this blog post for background information about the relationship between the chemical environment and life processes and systems in Fast Plants. Growing healthy Fast Plants is easy if you understand how the environment can affect growth and development. Three broad categories of environmental factors influence how an individual plant matures through its life cycle:  1) the physical environment, 2) the chemical environment, 3) the biological environment. Based on this information about standard conditions for optimal Fast Plants growth, one could easily design a wide variety of controlled experiments. Questions naturally arise while reading about optimal conditions that could be investigated by designing an experiment to how varying one condition affects growth, development and/or reproduction. This blog post is part of a series explaining how key environmental factors “physical, chemical, and biological" can impact the growth of Wisconsin Fast Plants.

Subject:
Agriculture
Career and Technical Education
Material Type:
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Hedi Baxter Lauffer
Date Added:
05/25/2023
Blogpost - Counting Leaf Hairs on Fast Plants for Selection Experiments
Conditional Remix & Share Permitted
CC BY-NC-SA
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This blog post from the Wisconsin Fast Plants website describes the observation of plant hairs (trichomes) for conducting a selective breeding experiment (such as in AP Biology investigations). The number of hairs is variable in Fast Plants seed varieties, and selection for or against plant hairiness is heritable, with measureable gain/loss from selection in offspring generations. This post describes strategies for identifying and counting plant hairs, including instructions for use of free ImageJ software.

Subject:
Genetics
Life Science
Material Type:
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Hedi Baxter Lauffer
Date Added:
05/25/2023
Blogpost - Dihybrid Inheritance Study - Open Source Educator Resources
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CC BY-NC-SA
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This blog post from the Wisconsin Fast Plants features open source educator resources, developed in 2023. These resources support the teaching of genetics concepts with tools focused on a Dihybrid Inheritance Study. This study provides a two-week approach for observing three generations of plant seedlings, germinated in Petri dishes. Observation of these three generations provides a model for inheritance of two traits found in Fast Plants seed varieties: Non-Purple Stem and Rosette-Dwarf. While observing traits in seedlings, students are guided to discuss norms for data collection and generate an evidence based model that explains the observed traits. This post is primarily a point of reference, giving background information about the Dihybrid Inheritance Study activity and providing links to free downloadable resources for teaching in your classroom. Resources include slideshows with photos of seedlings and discussion prompts, an implementation calendar, and handouts for preparation of Petri dishes in the classroom.

Subject:
Genetics
Life Science
Material Type:
Activity/Lab
Reading
Provider:
Wisconsin Fast Plants Program
Author:
Daniel W. Lauffer
Hedi Baxter Lauffer
Jackson Hetue
Date Added:
05/25/2023