Early detection of myocardial impairment in the setting of systemic lupus erythematosus

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "A new report published in Arthritis & Rheumatology suggests that cardiovascular disease affects patients with systemic lupus erythematosus much earlier than previously thought – in some cases even before active lupus sets in. The finding was reported by a team of researchers based in China who have been working on validating the use of magnetic resonance imaging to detect the early manifestations of cardiac impairment. With heart disease being the leading cause of death in patients with SLE, the ability to detect very early signs of cardiac dysfunction in this group could one day lay a foundation for enhanced preventive strategies. Traditional cardiac MRI approaches like late gadolinium enhancement don’t perform well in detecting early indications of heart disease, such as disturbances in myocardial extracellular volume. Missing these early warning signs could hide the fact that heart disease has set in and potentially complicate treatment efforts..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

PA domain of RNF43 is not necessary to suppress Wnt signaling in human cells

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "RNF43 is an enzyme frequently mutated in many forms of cancer. Under normal circumstances, the protein is known to inhibit canonical Wnt signaling, which regulates various aspects of cell development and disease. What remains controversial, however, is the function of a part of the protein known as the “protease-associated” (PA) domain. To find out, researchers recorded the effects of RNF43 without this domain in human cells. They discovered that the PA domain is not essential for RNF43 to block Wnt signaling. Rather, the PA domain’s job is to regulate levels of RNF43 on the cell surface, which is achieved through the pro-Wnt protein RSPO1. Understanding how RSPO1 behaves when RNF43 lacks its PA domain could be informative, as it could refine the perceived role of RNF43 mutations in human disease..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Protein phosphatases in TLR signaling

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "The activation of toll-like receptors (TLRs) is critical to detecting potentially harmful microbes, but overactivation can be life-threatening, leading to autoimmune and inflammatory diseases. While much research has been dedicated to positive regulators of TLR signaling, such as protein serine/threonine kinases, much less has focused on phosphatases, which counterbalance and limit TLR signaling. Fortunately, a growing number of studies are exploring the roles of these enzymes and how they might be harnessed to prevent excessive immune activation. Two important families of protein phosphatases are phospho-protein phosphatases (PPPs) and metal-dependent protein phosphatases (PPMs). PPPs contain a highly conserved catalytic core domain, which can combine with regulatory subunits to home in on specific enzymatic targets. PPMs, on the other hand, rely on magnesium or manganese ions and do not form multi-subunit complexes..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

tp53 mutation-induced dysbiosis causes inflammation by impairing sialic acid metabolism

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Mutations in the gene tp53 are often detected in the early stages of colitis-associated colorectal cancer (CAC). The development of CAC is facilitated by gut microbiota disruption (dysbiosis) and chronic intestinal inflammation, but whether tp53 mutations are linked to this dysbiosis and inflammation remains unclear. To learn more, a recent study examined zebrafish larvae with a tp53 mutation. The mutant fish exhibited intestinal inflammation that was due to gut microbiota disruption. confirming the link between tp53 and these pathological changes. Overall, gut microbiome diversity was decreased, while pathogenic Aeromonas bacteria were abnormally abundant, aggressively colonizing the gut. Further investigation revealed that the gut dysbiosis in the mutants induced inflammation by disrupting sialic acid metabolism. Supporting this finding, inhibition of the sialic acid-releasing enzyme sialidase alleviated the pathologies in mutant zebrafish larvae..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Scavenger receptors: Diverse defenders of host homeostasis

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "The scavenger receptors (SRs) are a group of surveillance proteins that play important roles in immune defense. These proteins are divided into 12 classes (A–L) on the basis of their diverse structures and functions. Their differences enable SRs to interact with a vast array of pathogenic factors, such as bacteria, to induce appropriate responses. Multiple SR types can bind to the same pathogenic signals, and an individual SR can bind multiple signal types. Furthermore, SRs can reversibly interact with co-receptor proteins to launch various responses, highlighting the complex and dynamic nature of SR-related defense. In general, SRs control the recruitment and activation of immune cells that eat harmful substances, and they can either induce or suppress inflammation depending on the conditions. Many SRs have both membrane-bound and soluble forms that accomplish their scavenging functions, while one potential SR, ACE-2, appears to scavenge only in its soluble form..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

You shall not pass [gas]: How blocking methane production affects the cow rumen microbiome

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Dairy cows emit large amounts of the greenhouse gas methane due to microbial fermentation in their stomachs, which poses an environmental problem. It also decreases the cows’ growth efficiency, as some energy from feed is lost as methane. The supplement 3-nitrooxypropanol (3-NOP) can help reduce methane emission by inhibiting a methane-forming enzyme, but 3-NOP’s effects on the microbiome in the rumen (the stomach compartment where fermentation occurs) haven’t been investigated. It’s also unclear why hydrogen gas (H₂) accumulates less than expected when methane production is blocked by 3-NOP. To learn more, researchers recently characterized the rumen microbes in 3-NOP-supplemented dairy cows. 3-NOP reduced the abundance of Methanobrevibacter species, which make methane from carbon dioxide. To a lesser extent, it also reduced the abundance of Methanosphaera species, which make methane from methanol..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

PARylation is crucial to NAT10’s role in the DNA damage response

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "The protein NAT10 has been implicated in the rapid-aging disease progeria and in human cancers. NAT10 normally resides in the nucleolus, an organelle within the nucleus that assembles cellular protein factories, but when DNA becomes damaged, NAT10 is translocated out of the nucleolus into the thick nuclear fluid, called the nucleoplasm. Researchers recently sought to clarify the mechanism of this translocation using several in vitro experiments. They found that the DNA damage response regulator PARP1 attached ADP-ribose molecules to NAT10 in a process called PARylation. Specifically, PARP1 mediated PARylation at three conserved amino acids within a sequence called the nucleolar localization signal (NuLS). Proper PARylation at these sites was essential for NAT10’s translocation to the nucleoplasm after DNA damage. and for NAT10’s interaction with the chromatin-modifying enzyme MORC2, which helps cells survive after DNA damage..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Metagenomics offers insight into marine sponge microbiomes

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Marine sponges and the microbial communities they host are critical to carbon and nutrient cycling in global reefs, and they often share unique, but poorly understood, symbiotic relationships. Lamellodysidea herbacea sponges, for example, obtain energy from photosynthetic Hormoscilla bacteria that live inside their bodies. These bacteria naturally produce compounds found in flame-retardant pollutants derived from consumer products. A new study describes how researchers are using metagenomics to understand how these creatures maintain a mutually beneficial relationship with sea sponges. Researchers obtained genetic material describing the relative abundance and metabolic capacities of 21 previously uncharacterized microbial populations associated with Lamellodysidea sponges. Analyses revealed genes coding for enzymes that break down halogenated aromatics, which could enable microbes to use pollutant-like compounds as carbon and energy sources..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Protective mechanism of the neurotransmitter NAAG against hypoxic ischemic injury

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Insufficient blood supply to the brain and a resulting oxygen shortage are collectively referred to as hypoxic ischemia (HI). During HI, accumulation of the neurotransmitter glutamate (Glu) in synapses can lead to neuron damage. Another neurotransmitter, NAAG, can help protect brain cells during HI by binding to the Glu receptor mGluR3 and preventing excess Glu signaling, but exactly how NAAG helps maintain synaptic networks isn’t clear. To learn more, researchers recently examined NAAG/Glu signaling and synaptic plasticity in the brains of newborn pigs subjected to HI via carotid artery clamping. The levels of NAAG and mGluR3 increased during HI, especially after 12–24 h, and then decreased, consistent with an initial anti-Glu defense mechanism. Next, the researchers inhibited the NAAG-degrading enzyme in piglets to increase brain NAAG levels..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Diet and gut microbiome interactions in irritable bowel syndrome

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders worldwide. IBS can have profound effects on quality of life, and treatment options are limited. While several studies have found associations between dietary habits and the gut microbiome in healthy individuals, studies in patients with IBS are limited. To better understand this relationship in IBS, researchers studied food diary data and sequenced gut microbiota in 149 individuals with IBS and 52 healthy controls. They found that individuals with IBS tended to show a higher intake of poorer quality food during main meals. Covariation between gut microbiota and diet corresponded with IBS symptom severity, exhaled gas, glycan metabolism, and meat/plant ratio, and IBS severity was associated with altered gut microbiota hydrogen production, with changes seen in enzymes involved in carbohydrate metabolism..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

New study points to target of future bladder cancer therapy

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Sialic acids are a family of sugars found throughout the body. They facilitate a variety of cellular functions such as interactions between cells and the detection of foreign bodies. But sialic acids are also linked to the progression of cancer, including bladder cancer. In a new study, researchers examined how bladder cancer cells rich in sialic acids respond to NEU1, one of several enzymes responsible for removing sialic acids from lipids and proteins. The team found that low NEU1 expression was linked to abnormally large amounts of sialic acids in cancer cells. In fact, low expression of NEU1 correlated with bladder cancer progression. High NEU1 expression, on the other hand, enhanced cancer cell death and decreased cancer proliferation. These findings were obtained for both cancer cells grown in the lab and cells extracted from mice with bladder cancer..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Inhibition of ABL tyrosine kinases shows potential for metastatic cancer treatment

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Cancer develops as a small cluster of abnormally replicating cells that form a tumor. As this tumor grows, cancerous cells may begin to invade other tissues in the body in a process called the “metastatic cascade”. During this advanced stage of cancer, aggressive cancer cells detach from the primary tumor, move through the bloodstream to other organs, and develop new tumors. Because such late-stage cancer is usually associated with a poor prognosis, preventing metastasis is critical to the development of effective cancer treatments. One promising area of research focuses on tyrosine kinases. Tyrosine kinases are enzymes with important roles in cell health when functioning normally, but those in the Abelson (ABL) family (ABL1 and ABL2) can promote tumor progression when abnormally activated. ABL1 and ABL2 affect how cells attach to one another as well as their orientation, thereby enabling previously stationary cells to become mobile and promoting the metastatic cascade..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Reduced expression of kappa opioid receptor drives metastasis in esophageal squamous cell carcinoma

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Esophageal cancers are common globally but are difficult to treat and have a poor prognosis. Esophageal squamous cell carcinoma (ESCC) is especially dangerous and has poorly understood molecular mechanisms. A recent study took a comprehensive look at the kappa opioid receptor (KOR), a protein that has been shown to influence the progression of other cancers. First, researchers examined existing patient datasets and found that ESCC tumors had reduced KOR expression and that lower expression of KOR was correlated with reduced patient survival. In the lab, they found that reducing KOR expression in cultured ESCC cells led to increased proliferation, invasion, and metastasis. When looking for potential mechanisms, they found that down-regulation of KOR activated the PDK1-AKT signaling pathway. It also led to invasion-related changes in cells, including invadopodia formation and cytoskeletal rearrangement. Reducing expression of KOR in mice led to increased metastasis and phosphorylation of the AKT enzyme..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

GDF-8 promotes placenta formation by upregulating MMP2 via Snail

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "During pregnancy, the placenta acts as a critical bridge between mother and child, providing oxygen and nutrients to the developing baby. One important process in placenta formation is “invasion” of the mother’s blood supply by placental cells called extravillous trophoblasts (EVTs). This process is promoted by the enzyme MMP2, whose expression is upregulated by the protein GDF-8, but the exact mechanism is unclear. To learn more, researchers recently examined GDF-8, MMP2, and cell invasion in human EVTs in vitro. They found that treatment with GDF-8 indeed stimulated MMP2 expression in the cells. This effect was blocked by an inhibitor of TGF-β type I receptors, indicating that the TGF-β pathway was involved. Further investigation revealed that the TGF-β signaling proteins Snail and Slug were also upregulated by GDF-8. However, silencing Snail and Slug expression individually showed that only Snail was required for GDF-8-mediated MMP2 stimulation..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Investigating heavy metal resistance in wastewater treatment microbes

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Wastewater treatment protects ecosystems from pollution, including dangerous heavy metal contaminants. Nitrogen and phosphorus can be removed from wastewater by denitrifying phosphorus removal sludge (DPRS). This artificial ecosystem contains many different microbes active in anaerobic, anoxic, and aerobic processes. However, heavy metal pollution can stop DPRS from reaching its full potential. So researchers examined DPRS microbiomes in response to Cr(VI), Ni(II), and Cd(II) contamination. Using metaproteomics, they found that different microbial groups adopted different resistance mechanisms. Nitrospira improved its oxygen utilization, and Nitrosomonas produced more enzymes under heavy metal stress. Phosphorus-accumulating bacteria also produced polyphosphate, which could support community-wide detoxification, and showed a variety of other resistance responses, illuminating different microbial responses to pollutants and how diversity within a community keeps it healthy..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Targeting AMPK to overcome resistance to anti-colorectal cancer drugs

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Antibody treatments such as cetuximab are powerful against colorectal cancer, but colorectal cancer cells are known to develop resistance to these drugs in large part due to to overactivation or mutation of the gene KRAS. To understand how KRAS might give rise to cetuximab resistance, researchers treated two types of lab-grown cells with the antibody, normal cancer cells and cancer cells containing a mutated KRAS gene. They then monitored the effects on AMPK, an enzyme that is toxic to various cancer cells. KRAS mutation impaired this AMPK-based defense, enabling mutant cancer cells to outlive normal cancer. Exposing cells with drugs known to activate AMPK, such as metformin, recovered the anti-cancer defense, overcoming the centuximab resistance induced by a mutated KRAS gene. That same mechanism was observed in colorectal tumors grafted onto mice. The results indicate that targeting AMPK could be a powerful therapeutic strategy, possibly boosting anti-cancer defenses in patients with colorectal cancer..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

The functional evolution of the termite gut microbial community

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Termites are one of the few animal lineages able to digest the most abundant biomolecule on earth, lignocellulose. Of the nine families of termites, all but one of them eat wood, with the last feeding on soil. While termites produce enzymes that break down lignocellulose, their gut microbes are still a critical part of the digestion process. But most termite gut microbiome research to date is based on research from wood-feeding or pest species of termites. So, a recent study examined the prokaryotic gut microbes from a sample of termite species that better represent the diversity of termites. The gut microbes possessed a similar set of carbohydrate and nitrogen metabolism genes across the termite phylogenetic tree. The proportions of these genes varied with the hosts’ diet and position on the phylogenetic tree. Surprisingly, the soil-feeding termites didn't even have unique microbial metabolic genes or pathways compared to wood-feeding species..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

Identifying new Helicobacter pylori HtrA targets in epithelial cells

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Gastric cancer is one of the highest mortality cancer types, and the leading cause of gastric cancer is persistent Helicobacter pylori infection. H. pylori secretes the enzyme HtrA, which cleaves adhesion proteins like E-cadherin and allows H. pylori to cross the epithelium. Recently, researchers used proteomics to find novel targets of HtrA associated with H. pylori. They confirmed E-cadherin as a target and identified human desmoglein-2 (hDsg2), neuropilin-1, ephrin-B2, and semaphorin-4D as potential targets. hDsg2 is a component of the desmosome junctions, which play important roles in epithelial cell-to-cell adhesion. Given the importance of cell-to-cell adhesion to epithelial health, the researchers focused on hDsg2. In vitro tests confirmed that HtrA secreted by H. pylori, and not other host cell proteases, cleaved hDsg2. This study is the first to demonstrate that HtrA secreted by H. pylori directly breaks down hDsg2 and suggests that HtrA is a ‘master key’ that allows H..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

The digestive tract as the origin of systemic inflammation

(View Complete Item Description)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview: "Could an imbalanced gut cause liver failure, lung injury, or pancreatitis in patients in intensive care? Though such events have historically been viewed in isolation, the importance of a properly functioning gut to overall well-being is becoming clearer. In a recent literature review, an international research team concluded that gastrointestinal failure is a potential cause of death in the critically ill – even in those without diseases originating from the gut. The gut’s crucial role in well-being hinges on its ability to absorb nutrients from food while also preventing harmful agents from entering the bloodstream. The specialized cells that line the gut and the community of microorganisms living therein are key to maintaining this harmony. Major trauma, surgery, or critical illness can weaken the gut barrier and disturb the delicate balance of microbes, leaking gut contents into other parts of the body and allowing pathogens to take hold..." The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Material Type: Diagram/Illustration, Reading

OpenStax Chemistry

(View Complete Item Description)

Chemistry is designed to meet the scope and sequence requirements of the two-semester general chemistry course. The textbook provides an important opportunity for students to learn the core concepts of chemistry and understand how those concepts apply to their lives and the world around them. The book also includes a number of innovative features, including interactive exercises and real-world applications, designed to enhance student learning. Coverage and scope Our Chemistry textbook adheres to the scope and sequence of most general chemistry courses nationwide. We strive to make chemistry, as a discipline, interesting and accessible to students. With this objective in mind, the content of this textbook has been developed and arranged to provide a logical progression from fundamental to more advanced concepts of chemical science. Topics are introduced within the context of familiar experiences whenever possible, treated with an appropriate rigor to satisfy the intellect of the learner, and reinforced in subsequent discussions of related content. The organization and pedagogical features were developed and vetted with feedback from chemistry educators dedicated to the project. Chapter 1: Essential Ideas Chapter 2: Atoms, Molecules, and Ions Chapter 3: Composition of Substances and Solutions Chapter 4: Stoichiometry of Chemical Reactions Chapter 5: Thermochemistry Chapter 6: Electronic Structures and Periodic Properties of Elements Chapter 7: Chemical Bonding and Molecular Geometry Chapter 8: Advanced Theories of Covalent Bonding Chapter 9: Gases Chapter 10: Liquids and Solids Chapter 11: Solutions and Colloids Chapter 12: Kinetics Chapter 13: Fundamental Equilibrium Concepts Chapter 14: Acid-Base Equilibria Chapter 15: Equilibria of Other Reaction Classes Chapter 16: Thermodynamics Chapter 17: Electrochemistry Chapter 18: Representative Metals, Metalloids, and Nonmetals Chapter 19: Transition Metals and Coordination Chemistry Chapter 20: Organic Chemistry Chapter 21: Nuclear Chemistry Pedagogical foundation and features Throughout Chemistry, you will find features that draw the students into scientific inquiry by taking selected topics a step further. Students and educators alike will appreciate discussions in these feature boxes. Chemistry in Everyday Life ties chemistry concepts to everyday issues and real-world applications of science that students encounter in their lives. Topics include cell phones, solar thermal energy power plants, plastics recycling, and measuring blood pressure. How Sciences Interconnect feature boxes discuss chemistry in context of its interconnectedness with other scientific disciplines. Topics include neurotransmitters, greenhouse gases and climate change, and proteins and enzymes. Portrait of a Chemist presents a short bio and an introduction to the work of prominent figures from history and present day so that students can see the “face” of contributors in this field as well as science in action.

Material Type: Textbook