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Discovering Genes Associated with Diseases and Traits in Dogs

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In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.

Material Type: Lecture

Author: Elinor Karlsson

Discovering Medicines, Using Robots and Computers

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Scientists who are working to discover new medicines often use robots to prepare samples of cells, allowing them to test chemicals to identify those that might be used to treat diseases. Students will meet a scientist who works to identify new medicines. She created free software that ''looks'' at images of cells and determines which images show cells that have responded to the potential medicines. Students will learn about how this technology is currently enabling research to identify new antibiotics to treat tuberculosis. Students will complete hands-on activities that demonstrate how new medicines can be discovered using robots and computer software, starring the student as ''the computer.'' In the process, the students learn about experimental design, including positive and negative controls.

Material Type: Lecture

Author: Anne Carpenter

Flu Math Games

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This video lesson shows students that math can play a role in understanding how an infectious disease spreads and how it can be controlled. During this lesson, students will see and use both deterministic and probabilistic models and will learn by doing through role-playing exercises. The primary exercises between video segments of this lesson are class-intensive simulation games in which members of the class 'infect' each other under alternative math modeling assumptions about disease progression. Also there is an occasional class discussion and local discussion with nearby classmates.

Material Type: Lecture

Authors: Mai Perches, Richard C. Larson, Sahar Hashmi

Genetics

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This science resource covers a variety of topics; however, the specific URL is on Genetics. It has significant explanations on the basic Principles of Genetics, Co-dominance, Incomplete dominance, and Sex-Linked traits. The units have precise and manageable explanations, and there are numerous links and additional resources to support instructors and students to advance learning. The access to videos and online simulations enhances particular areas, and the diverse assessments support mastery of skills. This is a very purposeful resource on genetics; it is useful to make learning more effective either as an overall instructional method or as an individualized learning supplement.

Material Type: Activity/Lab, Assessment, Case Study, Diagram/Illustration, Game, Interactive, Lecture, Lecture Notes, Lesson Plan, Primary Source, Reading, Simulation, Teaching/Learning Strategy, Textbook, Unit of Study

The Genetic Basis of Inheritance and Variation

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The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.

Material Type: Lecture

Author: Amjad Mahasneh

Growing Slime Mold

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This is a short activity for growing the slime mold Physarum polycephalum. It includes materials needed, a three-step procedure, and helpful tips. The site is part of the Turbulent Landscapes exhibit at the Exploratorium. Links to other activities and features of the exhibit are also included.

Material Type: Activity/Lab

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