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Gene Mutations
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Gene mutations occur naturally through the DNA replication process with some results being fatal and others being helpful.  This lesson will explore the types of mutations that occur, the effect they have on DNA, and examples of diseases or conditions caused by the specific type of mutation.  Students will participate in a gallery walk to learn more about the types of mutations. 

Subject:
Agriculture
Biology
Material Type:
Activity/Lab
Lesson
Author:
Abby Hitchler
Date Added:
07/07/2023
Human cerebral organoids provide new opportunities for cancer treatment development
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Organoids are 3-dimensional structures built in the laboratory from human pluripotent stem cells (hPSCs) to mimic human tissues and organs and have paved the way for research into new disease treatments that would never have been possible with traditional approaches. One field that is notably benefiting from the use of organoids is cancer research, particularly the study of glioma, the most common type of tumor originating in the brain. Poor outcomes are often associated with glioma because of its rapid growth and resistance to chemotherapy, but cerebral organoids hold promise for the development of novel treatments for this type of cancer, as they can be used as valuable tools to track tumor development and screen new drugs. Human cerebral organoids can also be grown from a patient’s own tissues for the creation of personalized cancer treatments, and they can be genetically engineered to study how common gene mutations affect tumor cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/13/2021