This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"The TAM subfamily of receptor kinases has been implicated in tumor development and progression. Their roles in efferocytosis, regulation of immune cells, secretion of inflammatory factors, and epithelial-to-mesenchymal transition make them key players in tumor development and progression. But TAM signaling is not always beneficial to tumor growth. In glioblastoma (GBM), the most prevalent and lethal primary brain tumor in adults it appears that TAM receptors may also have anti-tumor effects. While upregulation of TAM signaling is usually associated with GBM development, progression, and poor prognosis, TAM receptors may also activate pathways that trigger anti-tumor immune responses and their immunosuppressive role in the tumor microenvironment may obstruct GBM progression..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This example Socratic questioning page provides an outline for leading a classroom …
This example Socratic questioning page provides an outline for leading a classroom discussion regarding whether or not viruses are alive. Sample questions, resources for background information, and tips and assessment information are provided.
This video segment adapted from NOVA features a variety of scientific perspectives …
This video segment adapted from NOVA features a variety of scientific perspectives on the age old question, "Are we alone in the universe?" Animations make vivid the improbability that we could intercept a radio wave signaling extra terrestrial intelligence.
This lesson deals with human growth and our consumption of land resources. …
This lesson deals with human growth and our consumption of land resources. This lesson can be used in conjunction with other Are We Our Own Worst Enemy? lessons, although this should be first since it has the video of population growth. This lesson results from a collaboration between the Alabama State Department of Education and ASTA.
Students investigate the intelligence of dinosaurs by comparing the relative size of …
Students investigate the intelligence of dinosaurs by comparing the relative size of brain and body mass to living animals. Students plot the living animals to determine a general relationship of brain and body mass and then use that relation to interpret a range of dinosaurs. The activity gives students practice in graphical data comparison and other methods of data analysis. Students also investigate how well this method works and what weaknesses it might have.
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In this problem-based learning module, students will ‘dig’ for fossils in a digital …
In this problem-based learning module, students will ‘dig’ for fossils in a digital environment, using the advanced graphing techniques of line-of-best-fit and piecewise functions to look for different kinds of trends in the health of the history of the earth. They will apply this information to their knowledge of the laws of superposition and index fossils to form a complete analysis in the historical health as well as to predict where we are going in the future.
A lab activity evaluating the hypothesis that Earth's biosphere is currently undergoing …
A lab activity evaluating the hypothesis that Earth's biosphere is currently undergoing a mass extinction, the so-called "sixth extinction." Students practice quantitative skills by calculating extinction percentages and rates in recent history using real-world data from the work of Ceballos et al. (2015). Then, they integrate modern and fossil data to see whether recent extinctions more closely resemble a mass extinction or the background rate of extinction in the fossil record. In the process, students critically examine sources of error and uncertainty and reflect on how to resolve them.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"It’s a feared moment for every scientist: the discovery that years of painstaking research has led to results that can't be repeated. Many think that poorly characterized antibodies have contributed to this reproducibility crisis more than any other laboratory tool. A new study published in Molecular Cell supports this hypothesis, at least in the context of chromatin immunoprecipitation. Although accurate ChIP interpretation depends on near-perfect antibody specificity, the report shows that many of these reagents are far less capable than their advertising suggests, which calls into question several widely accepted paradigms on genomic regulation. The study focused on histone post-translational modifications; specifically all three methylation states of lysine 4 on histone H3. Through ChIP experiments, H3K4 methylation has been strongly linked to transcriptional control..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Deep-sea hydrothermal vent ecosystems host an array of macrofauna, including many invertebrates. These animals adapt to the extreme conditions by forging endosymbiotic relationships with chemoautotrophic bacteria. Phages, viruses that infect prokaryotes, can fundamentally affect endosymbiotic bacteria, but their specific roles in deep-sea vent endosymbionts are not yet known. A recent study utilized metagenomics, transcriptomics, and proteomics to examine the endosymbiotic phages associated with the deep-sea vent snail Gigantopelta aegis. These phages infected methane- and sulfur-oxidizing bacteria, and there was evidence of both lysogenic and lytic lifecycles. The genomes also showed evidence of an arms race between bacteria and phages, with the bacteria encoding defense systems like CRISPR–Cas to break down phage DNA and the phages encoding their own anti-defense mechanisms. The phages also had horizontally acquired auxiliary metabolic genes, which could benefit replication..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
If you’ve been paying attention so far in this series, you’ve probably …
If you’ve been paying attention so far in this series, you’ve probably heard of benzene. This molecule is flat, cyclic, and belongs to a special class of compounds known as aromatics. In this episode of Crash Course Organic Chemistry, we’ll learn all about aromatic compounds, their properties, reactivities, and some of the most important examples, like benzene. We’ll also revisit our friend NMR, and hear about some dubious science history!
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