This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Macroalgae and their surface microbes closely interact in integrated assemblages called holobionts. However, the interactions within these holobionts and the effects of environmental factors, especially in the context of coastal pollution, remain unclear. To clarify this issue, a recent multiomics study investigated the spatiotemporal dynamics of the holobiont of Taonia atomaria, a Mediterranean seaweed at sites with different levels of trace metal pollution. At all geographical sites, the surface bacterial communities were highly specific to the seaweed. The density and diversity of bacteria living on the seaweed at each site generally increased with the progression of time toward summer, but the proportions of core taxa and specific algal-enriched taxa decreased, suggesting the arrival of new colonizing bacteria. Notably, besides temperature, the copper concentration in the seawater was a key environmental factor shaping holobiont dynamics..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Probiotics are one strategy farmers use to boost animal production. These live microorganisms promote gut health, improve metabolism, and stave off harmful pathogens. While the effects of probiotics on the gut microbiomes of terrestrial animals have been extensively examined. less is known about their effects on the microbiomes of fish. To find out, researchers looked at multiple omics datasets, to explore how rainbow trout responded to feed containing probiotics and “synbiotics," mixtures of pre- and probiotics. A look at conventional measures of feed efficiency showed mixed results versus controls, such as decreases in weight gain (not significant) and protein efficiency (significant), but a significant increase in lipid efficiency. In the gut, pro- and synbiotic additives were associated with a decreased abundance of otherwise plentiful Mycoplasma bacteria..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"As the human population grows, so does the competition for resources between people and livestock. To meet the growing demand for dairy under these conditions, we need to optimize feed efficiency in dairy cattle. In ruminants, feed efficiency is determined by the ability of the rumen, and the microbes within it, to break down complex plant fibers. But the details of how the rumen microbiome contributes to feed efficiency are poorly understood. To close this gap, researchers examined the ruminal metagenomics, metatranscriptomics, and metabolomics of dairy cows with varying feed efficiency. Co-occurrence network analysis revealed that ‘high-efficiency’ animals had stronger and more numerous associations between microbes than animals with low feed efficiency. High-efficiency animals also showed positive interactions between members of the Selenomonas and Succinivibrionaceae bacterial families..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Male infertility due to toxin exposure is a serious health issue worldwide. However, the metabolic link between toxin exposure and testicular dysfunction is unclear. To learn more, a recent study examined the metabolic disruption associated with triptolide (TP)-induced testicular injury in mice. TP caused spermine (SP) deficiency by disrupting polyamine biosynthesis and uptake in the testes and by perturbing the gut microbiota. Exogenous SP supplementation reversed the TP-induced testicular dysfunction by increasing the expression of early and late spermatogenesis-related genes and by attenuating TP-induced decreases in offspring numbers. SP’s protective effect was found to be largely dependent on upregulation of HSP70 proteins in vivo and in vitro..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Type 2 diabetes mellitus often leads to muscle atrophy driven by diminished differentiation capacity in myoblasts. Myogenesis is complex, and while many involved pathways have been described, there may still be yet undiscovered therapeutic targets. With this goal in mind, a recent study combined experiments in diabetic mice and cultured myoblasts to identify key proteins in diabetes-induced atrophy. The gene for the relatively undescribed solute carrier Slc2a6, also known as glut6, was up-regulated during myogenic differentiation and down-regulated during diabetes-induced myopathy. Silencing Slc2a6 with RNAi in cell culture impaired differentiation and myotube formation. Transcriptomics and metabolomics revealed that Slc2a6 silencing disproportionally impacted the glycolysis pathway . Further experiments and analysis determined that Slc2a6 regulates myogenic differentiation in cultured myoblasts and that this regulation was partly through the glycolysis pathway..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.