A video that makes the unspoken assumptions that we use in pedigree analysis explicit through a skit of two students solving a challenging pedigree question over videoconference. The students discuss certain pedigree assumptions which are often not mentioned in other pedigree teaching materials, even though they can be important to solving complex problems. The students recognize that not all assumptions are always applicable and sometimes we need to reconsider which assumptions to use.Includes two videos: a version without subtitles and a version with subtitles

The advent of rapid methods for sequencing DNA has resulted in major advances in our understanding of the Evolution and distribution of a wide variety of marine organisms. Join Scripps researcher Ron Burton as he describes the surprising array of applications for these techniques in marine science. (56 minutes)

How will researchers harness the genetic potential of marine organisms? Join Dr. Terry Gaasterland as she describes how scientists at the new Scripps Genome Center are pioneering research in marine genomes. (54 minutes)

Join Mark Hildebrand on a journey from the open waters of the world's oceans to sophisticated genetics labs and ultimately to the incredible world of nanotechnology and marvel at ground-breaking applications he and his colleagues are finding for diatoms, one of the smallest and most important marine organisms. (49 minutes)

Understanding how the same genotype can still result in variation of phenotype based on environment.

In this activity, students are assigned different alleles of the gene for phenylalanine hydroxylase to research using OMIM (Online Mendelian Inheritance in Man). They are then asked to both explain and illustrate how this mutation may cause the disease phenylketonuria (PKU).

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The ability to label and manipulate proteins in the body is essential to modern biological research. Unfortunately, current methods, such as tagging with antibodies, are often inefficient and expensive. Even worse, researchers are realizing that many of the antibodies available just simply don’t work. Now, a new molecular tool could help researchers break through that barrier. Researchers in the Soderling Laboratory of the Cell Biology Department at Duke University, have developed a high-throughput system capable of modifying entire panels of proteins using a new dual-vector gene-editing approach. Dubbed Homology-independent Universal Genome Engineering, this system allows for the dynamic visualization and functional manipulation of proteins both in vitro and in vivo, including in neurons. This is HiUGE. HiUGE isn’t the first protein-modifying system to rely on gene editing..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

The higher the genetic diversity in a population, the more resilient the population is to environmental change. Created by Sal Khan.

This self-paced course was originally designed to help prepare incoming MIT students for their first Introductory Biology Course (known at MIT as 7.01). It will also be useful for anyone preparing to take an equivalent college-level introductory biology class elsewhere. It includes lecture videos, interactive exercises, problem sets, and one exam.  Lecture Topics: Molecules of Life, The Cell and How it Works, Information Transfer in Biology, Inheritance and Genetics, and Building with DNA.
Go to OCW’s Open Learning Library site for Pre-7.01: Getting up to Speed in Biology. The site is free to use, just like all OCW sites. You have the option to sign up and enroll in the course if you want to track your progress, or you can view and use all the materials without enrolling.

This textbook is designed specifically for Kansas State's Biology 198 Class. The course is taught using the studio approach and based on active learning. The studio manual contains all of the learning objectives for each class period and is the record of all student activities. Hence, this textbook is more of a reference tool while the studio manual is the learning tool.

This course presents the principles of evolution, ecology, and behavior for students beginning their study of biology and of the environment. It discusses major ideas and results in a manner accessible to all Yale College undergraduates. Recent advances have energized these fields with results that have implications well beyond their boundaries: ideas, mechanisms, and processes that should form part of the toolkit of all biologists and educated citizens.

In this project, you will explore a real-world problem, and then work through a series of steps to analyze that problem, research ways the problem could be solved, then propose a possible solution to that problem. Often, there are no specific right or wrong solutions, but sometimes one particular solution may be better than others. The key is making sure you fully understand the problem, have researched some possible solutions, and have proposed the solution that you can support with information / evidence.Begin by reading the problem statement in Step 1. Take the time to review all the information provided in the statement, including exploring the websites, videos and / or articles that are linked. Then work on steps 2 through 8 to complete this problem-based learning experience.

In this project, you will explore a real-world problem, and then work through a series of steps to analyze that problem, research ways the problem could be solved, then propose a possible solution to that problem. Often, there are no specific right or wrong solutions, but sometimes one particular solution may be better than others. The key is making sure you fully understand the problem, have researched some possible solutions, and have proposed the solution that you can support with information / evidence.Begin by reading the problem statement in Step 1. Take the time to review all the information provided in the statement, including exploring the websites, videos and / or articles that are linked. Then work on steps 2 through 8 to complete this problem-based learning experience.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"More than 1 million men are diagnosed with prostate cancer each year Although effective therapies exist, resistance to androgen receptor-targeted therapy is a major challenge in managing the disease Unfortunately, the mechanisms behind therapy resistance are not yet fully understood In a recent study, researchers aimed to identify new targets for treatment against therapy-resistant prostate cancer Using gene expression analysis and 3-dimensional spheroid culture, they examined the interaction of prostate cancer (PCa) cells with cancer-associated fibroblasts (CAFs) The results showed that CAFs in the tumor environment stimulate cholesterol and steroid production in PCa cells This was mediated by pro-inflammatory, pro-migratory, and pro-angiogenic factors secreted by the CAFs, which upregulated genes involved in cholesterol synthesis Blocking cholesterol and steroid production using gene targeting or medication inhibited PCa cell growth Future studies will evaluate the mechanisms underlying the.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

By the end of this section, you will be able to:Explain the basic principles of the theory of evolution by natural selectionDescribe the differences between genotype and phenotypeDiscuss how gene-environment interactions are critical for expression of physical and psychological characteristics

Watch how NJ high school students apply basic principles of molecular biology to solve real research problems, and publish their own genome research at GenBank, the international genomic sequence database.